Institution
Institut de veille sanitaire
Healthcare•Saint-Maurice, France•
About: Institut de veille sanitaire is a healthcare organization based out in Saint-Maurice, France. It is known for research contribution in the topics: Population & Public health. The organization has 1055 authors who have published 1547 publications receiving 56945 citations. The organization is also known as: INVS & InVS.
Papers published on a yearly basis
Papers
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TL;DR: This study aims to evaluate the validity of district-level estimations in France for 24 cancer sites, using health insurance data (ALD demands--Affection de Longue Durée) and to provide estimations when considered valid, using the ALD/I ratio.
19 citations
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TL;DR: On 28 August 2009, French authorities reported five cases of chikungunya fever on Reunion Island: three confirmed, one probable, and one suspected case under investigation.
Abstract: On 28 August 2009, French authorities reported five cases of chikungunya fever on Reunion Island: three confirmed, one probable, and one suspected case under investigation. All three confirmed patients presented with an acute febrile syndrome, arthralgia, myalgia and cutaneaous rash. All live in the same area on the western side of the island.
19 citations
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TL;DR: Assessment of factors influencingBCG vaccination among targeted children after the end of universal and mandatory BCG vaccination in France found that GPs with university training on infectious diseases tended to be more reluctant to follow vaccination guidelines.
19 citations
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TL;DR: Use of survival analysis is the most appropriate way to estimate failure rates with parasitological recurrence classified as treatment failure on the day it occurs, and the standard per-protocol method tended to overestimate the risk of failure when compared to alternative methods using the same endpoint definitions.
Abstract: Use of different methods for assessing the efficacy of artemisinin-based combination antimalarial treatments (ACTs) will result in different estimates being reported, with implications for changes in treatment policy. Data from different in vivo studies of ACT treatment of uncomplicated falciparum malaria were combined in a single database. Efficacy at day 28 corrected by PCR genotyping was estimated using four methods. In the first two methods, failure rates were calculated as proportions with either (1a) reinfections excluded from the analysis (standard WHO per-protocol analysis) or (1b) reinfections considered as treatment successes. In the second two methods, failure rates were estimated using the Kaplan-Meier product limit formula using either (2a) WHO (2001) definitions of failure, or (2b) failure defined using parasitological criteria only. Data analysed represented 2926 patients from 17 studies in nine African countries. Three ACTs were studied: artesunate-amodiaquine (AS+AQ, N = 1702), artesunate-sulphadoxine-pyrimethamine (AS+SP, N = 706) and artemether-lumefantrine (AL, N = 518). Using method (1a), the day 28 failure rates ranged from 0% to 39.3% for AS+AQ treatment, from 1.0% to 33.3% for AS+SP treatment and from 0% to 3.3% for AL treatment. The median [range] difference in point estimates between method 1a (reference) and the others were: (i) method 1b = 1.3% [0 to24.8], (ii) method 2a = 1.1% [0 to21.5], and (iii) method 2b = 0% [-38 to19.3]. The standard per-protocol method (1a) tended to overestimate the risk of failure when compared to alternative methods using the same endpoint definitions (methods 1b and 2a). It either overestimated or underestimated the risk when endpoints based on parasitological rather than clinical criteria were applied. The standard method was also associated with a 34% reduction in the number of patients evaluated compared to the number of patients enrolled. Only 2% of the sample size was lost when failures were classified on the first day of parasite recurrence and survival analytical methods were used. The primary purpose of an in vivo study should be to provide a precise estimate of the risk of antimalarial treatment failure due to drug resistance. Use of survival analysis is the most appropriate way to estimate failure rates with parasitological recurrence classified as treatment failure on the day it occurs.
19 citations
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TL;DR: Health surveillance systems can be used to trigger early warning systems, to create databases which improve scientific knowledge about the health impacts of climate change, to identify and prioritize needs for intervention and adaptation measures, and to evaluate these measures.
19 citations
Authors
Showing all 1055 results
Name | H-index | Papers | Citations |
---|---|---|---|
Serge Hercberg | 106 | 942 | 56791 |
Pilar Galan | 97 | 628 | 46782 |
Marcel Goldberg | 70 | 494 | 18659 |
Alexis Elbaz | 69 | 205 | 27260 |
Yannick Béjot | 57 | 331 | 33027 |
Emmanuelle Kesse-Guyot | 57 | 338 | 10914 |
Danielle Seilhean | 54 | 158 | 9153 |
Craig W. Hedberg | 49 | 149 | 12442 |
Jean-Claude Desenclos | 48 | 194 | 7230 |
Katia Castetbon | 46 | 236 | 12396 |
Sandrine Péneau | 44 | 158 | 5507 |
Francis Barin | 43 | 223 | 6235 |
Daniel Lévy-Bruhl | 43 | 221 | 6323 |
Véronique Vaillant | 41 | 117 | 4884 |
Pascal Guénel | 39 | 83 | 5055 |