Institution
Kagawa University
Education•Takamatsu, Japan•
About: Kagawa University is a education organization based out in Takamatsu, Japan. It is known for research contribution in the topics: Cancer & Population. The organization has 6028 authors who have published 11918 publications receiving 224111 citations. The organization is also known as: Kagawa Daigaku.
Topics: Cancer, Population, Angiotensin II, Gene, Lung cancer
Papers published on a yearly basis
Papers
More filters
••
TL;DR: Protein transduction therapy using polyarginine and HA2 may be useful as a method for cancer therapy because of the ability to efficiently translocate into the nucleus of glioma cells and induce p21WAF1 transcriptional activity more effectively.
139 citations
••
TL;DR: Recent progress in the studies on the enzymes involved in the biosynthesis and degradation of NAEs are discussed with special reference to NAAA, a lysosomal enzyme referred to as NAE-hydrolyzing acid amidase (NAAA) that may be a new target for the development of therapeutic drugs.
139 citations
••
TL;DR: The first part of this mini-review concentrates on the biochemistry of xylitol biosynthesis and the problems related to intracellular redox balance.
Abstract: The rare sugar xylitol is a five-carbon polyol (pentitol) that has beneficial health effects. Xylitol has global markets and, therefore, it represents an alternative to current dominant sweeteners. The research on microbial reduction of D-xylose to xylitol has been focused on metabolically engineered Saccharomycess cerevisiae and Candida strains. The Candida strains have an advantage over the metabolically engineered S. cerevisiae in terms of D-xylose uptake and maintenance of the intracellular redox balance. Due to the current industrial scale production of xylitol, it has become an inexpensive starting material for the production of other rare sugar. The first part of this mini-review concentrates on the biochemistry of xylitol biosynthesis and the problems related to intracellular redox balance.
139 citations
••
TL;DR: In this article, the impact of aeolian dust on climate via radiative forcing (RF) was investigated using field experiments and numerical simulations from the source regions in northwestern China to the downwind region in Japan in order to understand wind erosion processes temporal and spatial distribution of dust during their long-range transportation chemical, physical, and optical properties of dust and the direct effect of radiativeforcing due to dust.
138 citations
••
TL;DR: The results suggest that a supplement of D-psicose in the diet suppresses hepatic lipogenic enzyme activities, and the lower abdominal fat accumulation in rats fed a D-PSicose diet might result from lower lipogenesis in the liver.
Abstract: D-Psicose (D-ribo-2-hexulose), a C-3 epimer of D-fructose, is present in small quantities in commercial carbohydrate complexes or agricultural products. Wistar male rats were fed experimental diets which consisted of 5% D-psicose, cellulose, D-fructose or D-glucose for 28 days. Abdominal adipose tissue weight was significantly lower (P < 0.05) in rats fed the D-psicose diet than in rats fed a D-fructose and D-glucose diets, even though the four dietary groups were offered the same amount throughout the experimental period. Fatty acid synthase and glucose 6-phosphate dehydrogenase activities in the liver were significantly lower (P < 0.05) in rats fed the D-psicose diet than in rats fed the D-fructose and D-glucose diets. However, lipoprotein lipase activities in the heart, soleus muscle and perirenal adipose tissue were the same. These results suggest that a supplement of D-psicose in the diet suppresses hepatic lipogenic enzyme activities. The lower abdominal fat accumulation in rats fed a D-psicose diet might result from lower lipogenesis in the liver.
138 citations
Authors
Showing all 6051 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yuji Matsuzawa | 143 | 836 | 116711 |
Masatsugu Hori | 113 | 874 | 48028 |
Stewart T. Cole | 109 | 511 | 51942 |
Jian Feng Ma | 97 | 305 | 32310 |
H. Phillip Koeffler | 92 | 479 | 29428 |
Naoto Chatani | 87 | 597 | 26370 |
Takenobu Kamada | 86 | 700 | 27535 |
Juhn G. Liou | 83 | 301 | 21042 |
Hirofumi Makino | 82 | 803 | 30523 |
Jonathan W. Said | 78 | 437 | 25399 |
Junhua Li | 77 | 480 | 21626 |
Akira Nishiyama | 75 | 619 | 22487 |
Masayuki Fujita | 70 | 740 | 17847 |
Jun Hirabayashi | 66 | 270 | 15579 |
Mark R. Wormald | 64 | 179 | 14686 |