Medical University of Varna

About: Medical University of Varna is a education organization based out in Varna, Varna, Bulgaria. It is known for research contribution in the topics: Population & Medicine. The organization has 1199 authors who have published 1273 publications receiving 32940 citations. The organization is also known as: MU-Varna & Higher Medical Institute of Varna.

Significance of the DMF(T+t) index for the children with prematurely extracted teeth

Abstract: Premature extraction of temporary teeth is a consequence of different factors such as socio-economic status of the population, level of caries activity, oral hygiene, presence of fluoride in water, philosophy of the dentist. The aim of this article is to compare the DMF (T+t) between children with premature extraction and those without premature extraction. Subject of monitoring of the clinical research were 140 children between 6 and 9 years old. The clinical group consisted of 90 children with prematurely extracted teeth, divided into three groups. The control group consisted of 50 children with intact denture. The dental status was examined and registered according to the WHO by the DMF (T+t). There was a statistically significant difference in the distribution of caries DMF(T+t) between the control groups (2.34±019) and clinical groups (between 5.17±0.33 and 6.40±0.41). The children with premature extraction of temporary teeth had higher caries activity compared to the control group (children without early loss of teeth). The children with prematurely extracted temporary teeth and severe orthodontic deformation had the highest prevalence of DMF(T+t). These results demonstrate the connection between DMF(T+t), malocclusions and the need for prophylaxis.

Necrotizing periodontal disease - predisposing factors. A review

Abstract: Necrotizing gingivitis, necrotizing periodontitis and necrotizing stomatitis), are classified together under the common name necrotizing periodontal disease (NPD). The etiology is associated with bacterial infection (fusobacteria and spirochetes), but NPD is also predisposed by various factors: local (poor oral hygiene, pre-existing plaque-induced gingivitis, local trauma, smoking, alcohol abuse) and systemic factors (emotional stress, fatigue and insomnia, social economic status and altered host response, malnutrition or systemic diseases).

Polychlorinated biphenyls and organochlorine pesticides in black mussel and goby from Black Sea, Bulgaria

Abstract: Concentrations of persistent organic pollutants including polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) were measured in two marine species: black mussel (Mytilus galloprovincialis) and goby (Neogobius cephalarges). Samples were collected from Lake Varna and Varna Bay in the period of 2004 - 2005 in order to evaluate the status, spatial distribution and potential sources of pollution in these areas. The mussel, one of the most widely used bioindicators of persistent organic pollutants, has been used to monitor PCBs and DDTs contamination trends in Lake Varna and Varna Bay. Black sea gobies are non-migratory species and feed mainly with benthic organisms. Average PCB concentration in mussels were found 28.7 ng/g fat. Total PCB concentrations in goby varied in the range of 21.3 and 71.5 ng/g fat. Concentration in black mussel were found 28.7 ng/g fat for total DDTs. Average DDTs concentration in goby were measured 2116 ng/g fat. The levels of PCBs and DDTs in black mussels and goby from the Lake Varna and Varna Bay were comparable with those found in other marine ecosystems.

P53 Expression In Colorectal Epithelial Neoplasms And Its Relation To Clinical And Histopathological Features

Abstract: Увод: Колоректалният карцином (КРК) е резултат от генетични и епигенетични нарушения. Ген p53, известен като пазител на генома, играе важна роля в апоптозата и инхибиране на ангиогенезата. Цел: Целта на настоящото изследване е да се проучи и сравни експресията на р53 в туморната тъкан на синхронни/метахронни аденоми и КРК във връзка с клинико-морфологичните показатели и да се оцени р53 като предиктивен маркер. Материали и методи: Материали от 18 синхронни/метахронни колоректални аденоми и 21 КРК са фиксирани в 10% неутрален формалин и са включени в парафин. Срези с дебелина 5μ са оцветени с хемалаун-еозин за оценка на хистологичните параметри. За имунохистохимичния анализ е използвано моноклоналното заешко р53 антитяло (Clone Y5). Използвана е петстепенна скала за оценка процента на позитивни ядра: липсва експресия - 0 (0 - 5%), 1 (6 - 25%), 2 (26 - 50%) и 3 (51 - 75%) и 4 (>75%). Резултати: Седем (38.89%) от доброкачествените неоплазми са позитивни за р53 и експресията на протеина е в права корелационна зависимост от размера, локализация в дясната половина на колона и вилозната компонента на аденома и в обратна зависимост от степента му на диференциация (р 0.05). В нетуморната тъкан не се открива р53 позитивност. Заключение: Акумулирането на р53 е предиктор за малигнизация на колоректалните аденоми и за участие в аденом карциномната туморна прогресия.

Indications and optimal terms for primary hemarthroplasty in hip fractures

Abstract: Вътреставното счупване на бедрената шийка се среща предимно при възрастни пациенти над 75 години и съставлява 65% от всички счупвания на костите и 90% от тези на бедрената кост. Фрактурата на бедрената шийка при тази група пациенти обхваща 15%-25% от всички болни с травми на опорно - двигателния апарат, постъпили за болнично лечение. С напредването на възрастта е установено и нарастване броя на тези счупвания. Индицирането за първично хемипротезиране при пациентите в отделение по ортопедия към МБАЛ „Св.Анна Варна` е извършено по класификацията на Garden. Internal throat breakage occurs predominantly in adult patients over 75 years of age and accounts for 65% of all bone fractures and 90% of femur. The femoral neck fracture in this patient group covers 15% -25% of all patients with locomotor injuries received for hospital treatment. With the increase in age, an increase in the number of these fractures was also found. The indication for primary hemiprosis in the patients in the Orthopedic Department at St. Anne Varna Hospital was performed according to the classification of Garden.