Institution
Sunnybrook Health Sciences Centre
Healthcare•Toronto, Ontario, Canada•
About: Sunnybrook Health Sciences Centre is a healthcare organization based out in Toronto, Ontario, Canada. It is known for research contribution in the topics: Population & Medicine. The organization has 7689 authors who have published 15236 publications receiving 523019 citations. The organization is also known as: Sunnybrook.
Topics: Population, Medicine, Health care, Breast cancer, Cancer
Papers published on a yearly basis
Papers
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TL;DR: Neurally adjusted ventilatory assist (NAVA), a mode of mechanical ventilation controlled by diaphragmatic electrical activity (EAdi), may improve patient-ventilator interaction in low birth weight infants, even in the presence of large leaks.
Abstract: Neurally adjusted ventilatory assist (NAVA), a mode of mechanical ventilation controlled by diaphragmatic electrical activity (EAdi), may improve patient-ventilator interaction. We examined patient-ventilator interaction by comparing EAdi to ventilator pressure during conventional ventilation (CV) and NAVA delivered invasively and non-invasively. Seven intubated infants [birth weight 936 g (range, 676-1266 g); gestational age 26 wk (range, 25-29)] were studied before and after extubation, initially during CV and then NAVA. NAVA-intubated and NAVA-extubated demonstrated similar delays between onset of EAdi and onset of ventilator pressure of 74 +/- 17 and 72 +/- 23 ms (p = 0.698), respectively. During CV, the mean trigger delays were not different from NAVA, however 13 +/- 8.5% of ventilator breaths were triggered on average 59 +/- 27 ms before onset of EAdi. There was no difference in off-cycling delays between NAVA-intubated and extubated (32 +/- 34 versus 28 +/- 11 ms). CV cycled-off before NAVA (120 +/- 66 ms prior, p < 0.001). During NAVA, EAdi and ventilator pressure were correlated [mean determination coefficient (NAVA-intubated 0.8 +/- 0.06 and NAVA-extubated 0.73 +/- 0.22)]. Pressure delivery during conventional ventilation was not correlated to EAdi. Neural expiratory time was longer (p = 0.044), and respiratory rate was lower (p = 0.004) during NAVA. We conclude that in low birth weight infants, NAVA can improve patient-ventilator interaction, even in the presence of large leaks.
200 citations
TL;DR: There was a mild but significant increase in transvalvular gradients over time after TAVR, and the lack of anticoagulation therapy, a valve-in-valve procedure, a greater body mass index, and a 23-mm transcatheter valve were associated with higher rates of VHD post-TAVR.
200 citations
University of Ottawa1, Ottawa Hospital Research Institute2, University of Adelaide3, University of Toronto4, Jewish General Hospital5, University of British Columbia6, University of Melbourne7, Université de Montréal8, Dalhousie University9, University of Alberta10, Laval University11, University of Western Ontario12, McGill University13, York Hospital14, Queen's University15, McMaster University16, University of Saskatchewan17, Sunnybrook Health Sciences Centre18, Rowan University19, University of Utah20, University of Liverpool21, Brown University22
TL;DR: Dalteparin did not reduce the incidence of the primary composite outcome in both intention-to-treat and on-treatment analyses, and the occurrence of major bleeding did not differ between the two groups.
200 citations
TL;DR: ISB can provide effective analgesia up to 6 hours with motion and 8 hours at rest after shoulder surgery, with no demonstrable benefits thereafter.
Abstract: BACKGROUND:Interscalene block (ISB) can provide pain relief after shoulder surgery, but a reliable quantification of its analgesic benefits is lacking. This meta-analysis examines the effect of single-shot ISB on analgesic outcomes during the first 48 hours after shoulder surgery.METHODS:We retrieve
199 citations
TL;DR: It is suggested that matching or IPTW using the propensity score have shown to be most effective in reducing bias of the treatment effect.
199 citations
Authors
Showing all 7765 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Gordon B. Mills | 187 | 1273 | 186451 |
| David A. Bennett | 167 | 1142 | 109844 |
| Bruce R. Rosen | 148 | 684 | 97507 |
| Robert Tibshirani | 147 | 593 | 326580 |
| Steven A. Narod | 134 | 970 | 84638 |
| Peter Palese | 132 | 526 | 57882 |
| Gideon Koren | 129 | 1994 | 81718 |
| John B. Holcomb | 120 | 733 | 53760 |
| Julie A. Schneider | 118 | 492 | 56843 |
| Patrick Maisonneuve | 118 | 582 | 53363 |
| Mitch Dowsett | 114 | 478 | 62453 |
| Ian D. Graham | 113 | 700 | 87848 |
| Peter C. Austin | 112 | 657 | 60156 |
| Sandra E. Black | 104 | 681 | 51755 |
| Michael B. Yaffe | 102 | 379 | 41663 |