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Showing papers by "Universidade Federal de Santa Catarina published in 1997"


Book ChapterDOI
01 Jan 1997
TL;DR: This chapter introduces the finite element method (FEM) as a tool for solution of classical electromagnetic problems and discusses the main points in the application to electromagnetic design, including formulation and implementation.
Abstract: This chapter introduces the finite element method (FEM) as a tool for solution of classical electromagnetic problems. Although we discuss the main points in the application of the finite element method to electromagnetic design, including formulation and implementation, those who seek deeper understanding of the finite element method should consult some of the works listed in the bibliography section.

1,820 citations


Journal ArticleDOI
TL;DR: It is suggested that Lewis and SHR strains may constitute a useful model for studying the neurobiological mechanisms underlying the interindividual differences in baseline levels of anxiety.

480 citations


Journal ArticleDOI
TL;DR: Results indicate that tachykinin receptor antagonists, acting through NK1, NK2 and NK3 receptors, produce powerful antinociception when injected i.c.d. or by i.p., suggesting a distinct mechanism of action.

204 citations


Journal ArticleDOI
TL;DR: Serum can be used as an alternative for the study of the shrimp proPO activating system, as it is much more readily obtained than HLS, and its involvement in non-self recognition is suggested.
Abstract: In the present study we investigated the proPO activating system of the penaeid Penaeus paulensis, focusing on its role in the shrimp immune system. The great majority of PO activity (more than 90%) was found in the shrimp hemocytes. The enzyme activity was greatly enhanced by components of microorganism cell walls, such as LPS and beta-1,3-glucans, suggesting its involvement in non-self recognition. PO activity was also found in the shrimp serum and trypsin, and LPS were able to increase the enzyme activity. Thus, serum can be used as an alternative for the study of the shrimp proPO activating system, as it is much more readily obtained than HLS. PO activity was cation-dependent, and 5 mM of calcium and 10 mM of magnesium were the optimal concentrations for the enzyme activity. An immune factor was found in the shrimp HLS, capable of inducing cell-adhesion and degranulation of the penaeid hemocytes.

194 citations


Journal ArticleDOI
TL;DR: Acetyl aleuritolic acid exhibits the best minimum inhibitory concentration (MIC) against both Staphylococcus aureus and Salmonella typhimurium.

149 citations


Journal ArticleDOI
TL;DR: Vanilloid selective antagonists seem to be useful tools for investigating the nociception elicited by CAP and FM in mice, and administered by supraspinal site, both CPZ and RR were inactive in inhibiting FM, but prevented, in a graded manner, CAP-induced algesic response, suggesting the participation of distinct mechanisms in the nOCiception induced by FM and CAP.

126 citations


Journal ArticleDOI
TL;DR: In this paper, a complete family of two-switch pulsewidth-modulated (PWM) with active clamping DC/DC converters, featuring soft commutation of the semiconductors at zero-voltage (ZVS), is presented.
Abstract: This paper presents a technique to generate a complete family of two-switch pulsewidth-modulated (PWM) with active clamping DC/DC converters, featuring soft commutation of the semiconductors at zero-voltage (ZVS). The main purpose of this technique is to integrate these converters under a same theoretical principle to derive the topologies in a comprehensive form and generate new circuits. All the converters have the advantage of soft commutation (ZVS) with minimum switch voltage stress due to the clamping action. Besides operating at constant frequency and with reduced commutation losses, these converters have output characteristics similar to the PWM hard-switching counterpart, which means that there is no circulating reactive energy that would cause large conduction losses. Principle of operation, theoretical analysis, simulation and experimental results of one particular converter taken as an example, are provided in this paper.

123 citations


Journal ArticleDOI
TL;DR: The results show that the behavioral variability observed in rats, in social and nonsocial environments, is influenced by genetic factors and that the Behavioral reactivity to social stimulations is a specific feature, dissociable from the levels of the different components of emotionality (approach/avoidance and general activity) as evaluated by the behavioral responses to nonsocial settings.
Abstract: Male rats from six inbred rat strains (Spontaneously Hypertensive Rat, Wistar Kyoto, Brown Norway, Wistar Furth, Fischer 344, and Lewis) have been compared for their behavioral reactivity when placed in several nonsocial (elevated plus-maze, open field) and social (social interaction in aversive and neutral environment, resident–intruder test, chronic social stress) settings. In addition, a factorial analysis was performed to assess how the variables measured in these different tests related to each other. Besides significant strain-related differences in all tests, the factorial analysis showed that, in nonsocial environments, the strains contrasted essentially along two independent behavioral traits, the propensity to approach or avoid an aversive stimulus and general motor activity in novel environments (two indices of emotionality). In the social settings, marked interstrain differences were observed regarding the expression of aggressive behaviors but these differences were not related to the respective levels on the two nonsocial components of reactivity. Furthermore, large genetic differences were observed in variations of body weight induced by a chronic social stressor paradigm. The factorial analysis suggested a lack of relationship between the effect of social stressors on body weight and the measures of emotionality and general activity obtained in the nonsocial tests. Conversely, these variations were influenced by the levels of aggressiveness and sociability. Taken together, these results show (i) that the behavioral variability observed in rats, in social and nonsocial environments, is influenced by genetic factors and (ii) that the behavioral reactivity to social stimulations is a specific feature, dissociable from the levels of the different components of emotionality (approach/avoidance and general activity) as evaluated by the behavioral responses to nonsocial settings.

120 citations


Journal ArticleDOI
01 Mar 1997-Headache
TL;DR: Although most patients with migraine with aura had a combination of phenomena, the majority had only one uniform constellation of manifestations and there was no clear‐cut relationship between side of VA and side of HA.
Abstract: Visual auras (VAs) of 100 patients with migraine with aura were studied by questionnaire. Visual auras accompanied the patients' first headache (HA) in 39% of patients. Only 19% had VAs with every attack. Patients with VAs over the entire HA history had a high frequency (greater than 50%) of attacks with VA; patients with VA during only part of the HA history had a low frequency (less than 50%} of attacks with VA. The auras occurred exclusively prior to the HA in 57%. The free interval between the end of the VA and the start of the HA was usually (75%) shorter than 30 minutes. Most (59%) patients had VAs that lasted from 1 to 30 minutes. They started in the periphery of the visual fields in 56%. The most common phenomena described were: small bright dots (42%), flashes of light (39%), “blind spots” (32%), and “foggy vision” (27%). Fortification spectra was reported by only 20%. Although most (65%) patients had a combination of phenomena, the majority (72%) had only one uniform constellation of manifestations. There was no clear-cut relationship between side of VA and side of HA. Migraine VA is a pleomorphic and complex symptom. Many patients not qualifying for the diagnostic criteria of migraine with aura, as proposed by the International Headache Society (IHS) unequivocally present with visual phenomena that strongly suggest this diagnosis.

105 citations


Journal ArticleDOI
TL;DR: The principle of operation, theoretical analysis, and experimental results of the new ZCS-PWM boost converter are provided in this paper to verify the performance of this new family of converters.
Abstract: This paper presents a new family of pulsewidth-modulated (PWM) converters, featuring soft commutation of the semiconductors at zero current (ZC) in the transistors and zero voltage (ZV) in the rectifiers. Besides operating at constant frequency and with reduced commutation losses, these new converters have output characteristics similar to the hard-switching-PWM counterpart, which means that there is no circulating reactive energy that would cause large conduction losses. The new family of zero-current-switching (ZCS)-PWM converters is suitable for high-power applications using insulated gate bipolar transistors (IGBTs). The advantages of the new ZCS-PWM boost converter employing IGBTs, rated at 1.6 kW and operating at 20 kHz, are presented. This new ZCS operation can reduce the average total power dissipation in the semiconductors practically by half, when compared with the hard-switching method. This new ZCS-PWM boost converter is suitable for high-power applications using IGBTs in power-factor correction. The principle of operation, theoretical analysis, and experimental results of the new ZCS-PWM boost converter are provided in this paper to verify the performance of this new family of converters.

97 citations


Journal ArticleDOI
TL;DR: In this paper, the authors introduced a new family of zero-voltage switching (ZVS) pulsewidth modulation (PWM) active-clamping DC-to-DC boost power converters.
Abstract: The purpose of this paper is to introduce a new family of zero-voltage switching (ZVS) pulse-width modulation (PWM) active-clamping DC-to-DC boost power converters. This technique presents ZVS commutation without additional voltage stress and a significant increase in the circulating reactive energy throughout the power converters. So, the efficiency and the power density become advantages when compared to the hard-switching boost power converter. Thus, these power converters may become very attractive in power factor correction applications. In this paper, the complete family of boost power converters is shown, and one particular circuit, taken as an example, is analyzed, simulated and experimented. Experimental results are presented, taken from a laboratory prototype rated at 1600 W, input voltage of 300 V, output voltage of 400 V, and operating at 100 kHz. The measured efficiency at full load was 98%, and the power converter kept an efficiency up to 95% from 17% to 100% of full load, without additional voltage and current stresses.

Journal ArticleDOI
TL;DR: In this article, the authors examine current hegemonic concepts which see health as a question of balance and adjustment to the environment, including the conceptualization posed by the World Health Organization and the broad definition laid out during the 8th Health Conference and show that what is defined in discursive statements constitutes an ongoing interaction with the metadiscursive statements more closely related to the world of institutions and institutional action.
Abstract: Taking as a point of departure Canguilhem's view on the epistemological status of the concept of health, the article examines current hegemonic concepts which see health as a question of balance and adjustment to the environment-including herein the conceptualization posed by the World Health Organization and the broad definition laid out during the 8th Health Conference. The basic goal of this examination is to show that what is defined in discursive statements constitutes an ongoing interaction with the metadiscursive statements more closely related to the world of institutions and institutional action. It is therefore argued that the adoption of a particular notion of health implies the selection of a particular direction in health care policies as well as the application of a particular set of intervention strategies regarding the lives and bodies of subjects.

Journal ArticleDOI
TL;DR: In this article, the phase diagram of the two-dimensional Blume-Capel model with a random crystal field is investigated within the framework of a real-space renormalization-group approximation.
Abstract: The phase diagram of the two-dimensional Blume-Capel model with a random crystal field is investigated within the framework of a real-space renormalization-group approximation. Our results suggest that, for any amount of randomness, the model exhibits a line of Ising-like continuous transitions, as in the pure model, but no first-order transition. At zero temperature the transition is also continuous, but not in the same universality class as the Ising model. In this limit, the attractor (in the renormalization-group sense) is the percolation fixed point of the site diluted spin-1/2 Ising model. The results we found are in qualitative agreement with general predictions made by Berker and Hui on the critical behavior of random models.

Journal ArticleDOI
TL;DR: The present studies were undertaken to elucidate the anatomical and neurotransmitter organization of the pterygopalatine ganglion input to orbital and choroidal blood vessels in pigeons.
Abstract: Orbital and choroidal blood vessels in mammals are known to receive a parasympathetic innervation from the pterygopalatine ganglion, which appears to utilize vasoactive intestinal polypeptide (VIP) and nitric oxide (NO) to increase choroidal blood flow. The present studies were undertaken to elucidate the anatomical and neurotransmitter organization of the pterygopalatine ganglion input to orbital and choroidal blood vessels in pigeons. Single- or double-label immunohistochemistry were employed on paraformaldehyde-fixed cryostat sections of the pigeon eye and surrounding orbital tissue to localize 1) VIP+ neurons and fibers; 2) choline acetyltransferase (CHAT)-containing cholinergic neurons and fibers; 3) axons containing the 3A10 neurofilament-associated antigen; and 4) neuronal NO synthase (nNOS)-containing neurons and fibers. NOS+ neurons and fibers were also identified by NADPH-diaphorase histochemistry in sections and whole-mount specimens. The pterygopalatine ganglion was found to consist of an interconnected series of three to four main microganglia of about 50-200 neurons each and numerous lesser microganglia. The major microganglia of the pterygopalatine network in pigeon lie along the superior aspect of the Harderian gland, with many additional fibers and microganglia of the network encircling the gland. Neurons of all microganglia were extremely rich in VIP, nNOS, and NADPH-diaphorase and moderate in CHAT. The majority of the pterygopalatine ganglion neurons were observed to co-contain VIP and nNOS. Axons labeled for VIP, nNOS, NADPH-diaphorase, or the 3A10 antigen could be traced from the pterygopalatine ganglion network to perivascular fiber plexi on orbital blood vessels. These orbital vessels, many of which enter the choroid posteriorly and nasally, appear to be a conduit by which pterygopalatine postganglionic fibers reach the choroid. The pterygopalatine postganglionic fibers were also seen to innervate the Harderian gland and contribute branches to the nearby ophthalmic nerve. Within the choroid, VIP+ fibers were widely scattered and sparse but were most abundant in nasal choroid. A few VIP+ and NADPH- diaphorase+ neurons were also observed in the choroid. These results suggest that pterygopalatine ganglion neurons of birds use VIP and NO to exert vasodilatory control over blood flow to and within the avian choroid. J. Comp. Neurol. 386:422-442, 1997. © 1997 Wiley-Liss, Inc.

Journal ArticleDOI
TL;DR: The results indicate that the herbal medicine Catuama may constitute a useful therapeutic agent for the treatment of clinical pain.
Abstract: The antinociceptive effect of the herbal medicine Catuama and the hydroalcoholic extract (HE) of each plant present in this extract were investigated in chemical and thermal models of nociception in mice. The extract of Catuama (200 mg/kg, p.o.) caused time-dependent and long-lasting antinociception against acetic acid-induced writhing, formalin and capsaicin-induced licking and also in the tail-flick and hot-plate assays. Its maximal analgesic effect was reached 6 h after its oral administration and this effect lasted for at least 12 h. When given 6 h prior to testing (100 and 200 mg/kg, p.o.), the extract elicited dose-related antinociception, but at 400 mg/kg, its analgesic effect was greatly reduced. The antinociception caused by the extract of Catauma, like those produced by morphine, was largely antagonized by naloxone. The daily administration of the extract (200 mg/kg, p.o. for 4 days) or morphine (5 mg/kg, s.c. for 4 days) produced progressive tolerance, an effect which was reverted by naloxone (5 mg/kg, i.p.). In addition, the Catuama extract showed cross-tolerance with morphine. The Catuama antinociception was not due to its non-specific effects such as muscle relaxation or sedation of animals, nor was it secondary to its antiinflammatory property. When analysed separately the hydroalcoholic extract (HE) obtained from Trichilia catigua, Paullinia cupana, Ptychopelatum olacoids, Zinziber officinalis (200 mg/kg, p.o., 6 h prior) all inhibited acetic acid-induced pain (82%±2%; 66%±2%; 42%±2% and 30%±4% of inhibition, respectively (p<0.01). In the formalin test the HE of P. olacoids; P. cupana; T. catigua and to a lesser extent, Z. officinalis (200 mg/kg, p.o., 6 h prior) also inhibited both phases of formalin-induced pain (p<0.01). Thus, antinociception caused by the Catuama extract seems to be dependent on the interaction of the several active principles present in these plants. The mechanisms underlying the antinociception caused by extract of herbal medicine Catuama is still not completely understood, but a significant number of these effects are related to its interaction with the naloxone sensitive opioid system. Together, the results indicate that the herbal medicine Catuama may constitute a useful therapeutic agent for the treatment of clinical pain. © 1997 by John Wiley & Sons, Ltd.

Journal ArticleDOI
TL;DR: The data show that the active principle(s) present in the HE of P. cyparissias, at antinociceptive doses, did not affect motor coordination of animals when assessed in the rota-rod model and was able to prevent bradykinin and substance P-induced hyperalgesia.

Journal ArticleDOI
TL;DR: It is suggested that CH2Cl2 extract has potent anti-inflammatory and analgesic action and that F-III and cucurbitacin B and E may account for these actions.
Abstract: The anti-inflammatory and antinociceptive actions of the CH2Cl2 extract and semipurified fraction (F-III) from roots of Wilbrandia ebracteata Cogn. have been investigated in rats and mice. The CH2Cl2 extract (1-10 mg/kg, i.p.; ID50 5 mg/kg) and (3-30 mg/kg, p.o.; ID50 15 mg/kg) inhibited, in a dose-related manner, carrageenan-induced paw edema in rats. The subfraction (F-III) from CH2Cl2 extract and compounds isolated as cucurbitacin B and E also inhibited carrageenan-induced edema. The CH2Cl2 extract and F-III also exhibited significant analgesic action in acetic acid-induced pain in mice. In the formalin test, the CH2Cl2 extract (0.3-10 mg/kg, i.p.) and (3-30 mg/kg, p.o.) caused inhibition of the neurogenic (first phase) and inflammatory phase (second phase) of formalin-induced pain. However, the CH2Cl2 extract was more effective in relation to the second phase than in inhibition of the formalin-induced edema. These findings suggest that CH2Cl2 extract has potent anti-inflammatory and analgesic action and that F-III and cucurbitacin B and E may account for these actions.

Proceedings ArticleDOI
22 Jun 1997
TL;DR: In this paper, the authors present a technique for single phase power factor correction of nonlinear loads employing an active power filter, which allows compensation of harmonics and phase displacement of the input current, for single and multiple nonlinear and linear loads.
Abstract: This paper presents a technique for single phase power factor correction of nonlinear loads employing an active power filter. The current control strategy is the same used in the boost pre-regulator, which is the average current mode technique. The paper focuses on the design methodology and the analysis of the control strategy which allows the compensation of harmonics and phase displacement of the input current, for single and multiple nonlinear and linear loads. Simulation results of an active filter controlling a single load, which consists of a 1600 W rectifier with a capacitive filter, and a multiple load, which consists of a 800 W rectifier with a capacitive filter and a 800 W AC chopper, are provided. Experimental results of an active filter controlling a 400 W rectifier with a capacitive filter, a 800 W AC chopper and a 580 W multiple load, which consists of a rectifier with a capacitive filter and an AC chopper, are presented.

Journal ArticleDOI
TL;DR: ET-1 potentiates formalin-induced nociception and edema in the mouse and these actions are possibly mediated via ETB and ETA receptors, respectively, but their true identity and the mechanisms involved still remain to be fully elucidated.
Abstract: La presente etude examine l'effet des peptides apparentes aux endothelines (ET) (0,3 a 30 pmol/patte) sur les deux phases de la nociception et l'oedeme induits par l'injection intraplantaire de formalin (0,5 % dans 20 μL) dans la patte arriere de la souris. La premiere phase de la nociception (de 0 a 5 min apres l'injection) a ete significativement potentialisee par l'injection simultanee de ET-I (10 ou 30 pmol/patte) ou de ET-3 (10 pmol/patte), mais pas de l'agoniste selectif du recepteur ET B , sarafotoxine S6c (SRTX-c; jusqu'a 30 pmol/patte). Les trois peptides ont potentialise la deuxieme phase (de 10 a 30 min apres l'injection) de la nociception induite par la formalin (3 a 30, 1 a 30 et 10 a 30 pmol/patte pour ET-1, ET-3 et SRTX-c, respectivement), alors que seule ET-I (10 ou 30 pmol/patte) a stimule efficacement l'oedeme induit par la formalin (30 min apres l'injection). L'histamine a aussi potentialise les 3 reponses declenchees par la formalin, mais elle a ete d'un facteur 30 a 100 moins puissante que ET-1. Le traitement avec l'antagoniste des recepteurs ET A /ET B , bosentan (10 mg/kg, i.p., 1 h plus tot) n'a pas influence les reponses oedematogenes et nociceptives a la formalin ni leur potentialisation par l'histamine (3 nmol/patte), mais il a inhibe les potentialisations induites par ET-I (10 pmol/patte). Ainsi, ET-1 potentialise la nociception et l'oedeme induits par la formalin chez la souris. Ces actions sont probablement vehiculees par les recepteurs ET B et ET A , respectivement, mais leur identite reelle et les mecanismes mis en jeu n'ont pas ete totalement elucides.

Journal ArticleDOI
TL;DR: Mollusca, Polychaeta and Crustacea were observed to be basic elements in the species diet, Osteichthyes and MOND appear as secondary resource whereas vegetal material were found to be of less importance.
Abstract: From March/91 to February/92 monthly collcction surveys were carried out to obtain basic information about the dynamics of feeding and trophic spectrum of C. danae Smith, 1869. A total of 456 males and 527 females were caught. The diet of the species was not sex related. The trophic spectrum of C. danae is composed by a high number of items. The 35 items were assembled in 14 categories and the feeding index was applied. Mollusca, Polychaeta and Crustacea were observed to be basic elements in the species diet, Osteichthyes and MOND appear as secondary resource whereas vegetal material were found to be of less importance.

Journal ArticleDOI
TL;DR: In this article, a weak coupled modeling between electrical and thermal phenomena is proposed, taking into account the transient states of the motor and the air gap in the stator coil for thermal analysis.
Abstract: Thermal analysis is an important step in designing induction motors. Its principles require the calculation of induced currents in the rotors and obviously this phenomenon is connected to heating. Currents circulating in the stator coil also heats the machine. In this work, in order to evaluate the thermal behaviour of the machine, a weak coupled modeling between electrical and thermal phenomena is proposed, taking into account the transient states. Also, in this work we introduce a new approach to take into account the airgap zone for thermal analysis. Experimental results are presented and compared with calculations.

Journal ArticleDOI
TL;DR: The results confirm and extend the previous studies, and demonstrate the clear oral anti-inflammatory and anti-allergic properties of the active principle(s) present in the barks of D. winteri, thus confirming its reported medicinal use in folk medicine for the management of airway diseases.
Abstract: Objective: To study the acute anti-inflammatory and anti-allergic properties of an extract of D. winteri.¶Material and Methods: Paw oedema induced in rats with various stimuli and anaphylactic shock in mice.¶Results: The hydroalcoholic extract (HE) of D. winteri (Winteraceae) (30 to 100 mg/kg, p.o., 1 h prior) inhibited carrageenan (300 μg/paw) and dextran (100 μg/paw)-induced paw oedema formation in a dose-dependent manner, with mean ID50 values of 49 and < 30 mg/kg, respectively. The HE of D. winteri (30 to 100 mg/kg) also inhibited paw oedema induced by bradykinin (BK) (3 nmol), substance P (SP) (10 nmol) and PAF-acether (PAF) (10 nmol), in a dose-dependent manner, with mean ID50 values of 56, 63, and 58 mg/kg, respectively. However, the HE inhibited the rat paw oedema induced by prostaglandin E2 (PGE2) (10 nmol) (29 ± 7 and 33 ± 2% at 60 and 240 min) to a smaller extent, and had no effect on oedema elicited by histamine (100 nmol). In adrenalectomized animals, the inhibition by the HE of D. winteri (100 mg/kg, p.o., 1 h prior) of BK-elicited oedema (3 nmol/paw) was significantly smaller when compared with that observed in control animals. When assessed in rats actively sensitised to ovalbumin (OVO), the oedema caused by OVO (6 μg/paw) was significantly inhibited by HE of D. winteri (30 to 100 mg/kg, p.o.), with a mean ID50 of about 65 mg/kg. The HE of D. winteri (100 and 200 mg/kg, p.o.) significantly increased survival rate when assessed in anaphylactic shock in mice actively sensitised to the antigen. The protective effect was long-lasting, being observed for up to 15 h. Dexamethasone, used as positive control (0.5, 1 and 2 mg/kg) produced a long-lasting (up to 24 h) increase in the survival rate of the animals.¶Conclusions: These results confirm and extend our previous studies, and demonstrate the clear oral anti-inflammatory and anti-allergic properties of the active principle(s) present in the barks of D. winteri, thus confirming its reported medicinal use in folk medicine for the management of airway diseases.

Journal ArticleDOI
TL;DR: The results suggest that SCA may be occasionally caused by the SCA1 and SCA2 mutations in the Brazilian population, and that the MJD/SCA3 mutation is the most common cause of dominantly inherited SCA in Brazil.
Abstract: Spinocerebellar ataxia type 1 (SCA1), spinocerebellar ataxia type 2 (SCA2) and Machado-Joseph disease or spinocerebellar ataxia type 3 (MJD/SCA3) are three distinctive forms of autosomal dominant spinocerebellar ataxia (SCA) caused by expansions of an unstable CAG repeat localized in the coding region of the causative genes. Another related disease, dentatorubropallidoluysian atrophy (DRPLA) is also caused by an unstable triplet repeat and can present as SCA in late onset patients. We investigated the frequency of the SCA1, SCA2, MJD/SCA3 and DRPLA mutations in 328 Brazilian patients with SCA, belonging to 90 unrelated families with various patterns of inheritance and originating in different geographic regions of Brazil. We found mutations in 35 families (39%), 32 of them with a clear autosomal dominant inheritance. The frequency of the SCA1 mutation was 3% of all patients; and 6 % in the dominantly inherited SCAs. We identified the SCA2 mutation in 6% of all families and in 9% of the families with autosomal dominant inheritance. The MJD/SCA3 mutation was detected in 30 % of all patients; and in the 44% of the dominantly inherited cases. We found no DRPLA mutation. In addition, we observed variability in the frequency of the different mutations according to geographic origin of the patients, which is probably related to the distinct colonization of different parts of Brazil. These results suggest that SCA may be occasionally caused by the SCA1 and SCA2 mutations in the Brazilian population, and that the MJD/SCA3 mutation is the most common cause of dominantly inherited SCA in Brazil.

Journal ArticleDOI
TL;DR: This paper is the synthesis of the author master program in administration thesis, which studied the pleasure, suffering and work relationship and searched to establish the implications of work itself, work organization and offered work conditions in the feelings of pleasure and suffering of nursing workers.
Abstract: O presente texto constitui-se numa sintese da Dissertacao de Mestrado em Administracao "Prazer e sofrimento no trabalho: contribuicoes a organizacao do processo de trabalho da enfermagem". Este trabalho de pesquisa teve como objeto de estudo a relacao prazer, sofrimento e trabalho. Procurou estabelecer as implicacoes do trabalho em si, de sua organizacao e das condicoes oferecidas para seu desenvolvimento nos sentimentos de prazer e sofrimento dos trabalhadores da area de enfermagem.



Journal ArticleDOI
22 Jun 1997
TL;DR: In this paper, a single-phase high-power-factor (HPF) pulsewidth-modulated (PWM) boost rectifier featuring soft commutation of the active switches at zero current (ZC) is presented.
Abstract: This paper presents a novel single-phase high-power-factor (HPF) pulsewidth-modulated (PWM) boost rectifier featuring soft commutation of the active switches at zero current (ZC) It incorporates the most desirable properties of conventional PWM and soft-switching resonant techniques The input current shaping is achieved with average current mode control and continuous inductor current mode This new PWM power converter provides ZC turn on and turn off of the active switches, and it is suitable for high-power applications employing insulated gate bipolar transistors (IGBTs) The principle of operation, the theoretical analysis, a design example and experimental results from a laboratory prototype rated at 1600 W with 400 VDC output voltage are presented The measured efficiency and the power factor were 962% and 099%, respectively, with an input current total harmonic distortion (THD) equal to 394%, for an input voltage with THD equal to 38%, at rated load

Journal ArticleDOI
TL;DR: Improvements, are necessary among men and members of low social class in relation to socio-demographic variables, as oral hygiene habits were considered good for most of the participants of the study.
Abstract: OBJETIVOS: Avaliar alguns habitos de higiene bucal (escovacao dentaria, uso do palito e uso do fio dental) em um grupo de adultos, em relacao a fatores sociodemograficos, e investigar o nivel de placa bacteriana e sangramento gengival. METODOLOGIA: A amostra foi constituida por 234 mulheres e 237 homens de duas categorias socioeconomicas, com idade entre 24 e 44 anos. Os dados foram coletados atraves de entrevistas estruturadas e exames clinicos. RESULTADOS: A frequencia de escovacao encontrada foi alta: (mediana e moda de tres vezes ao dia) e apresentou associacao com sexo e categoria socioeconomica. A maioria dos entrevistados (67,5%) declarou usar fio dental, estando seu uso associado com sexo e categoria socioeconomica. Usar palito foi descrito como um habito comum para a maioria das pessoas entrevistadas:(54,6%) o usam. O uso do palito apresentou associacao com sexo, idade e categoria socioeconomica . O nivel de placa bacteriana foi moderado para a maioria das pessoas (62,6%), e estava associado com a categoria socioeconomica. Um quarto dos participantes do estudo nao apresentou sangramento gengival, e este estava associado com a idade e a categoria socioeconomica. CONCLUSAO: Os habitos de higiene bucal foram considerados bons para a maioria dos individuos que participaram do estudo, havendo necessidade de melhoria para os homens e pessoas de categoria socioeconomica inferior.

Journal ArticleDOI
TL;DR: The results indicate that bradykinin had a significant pro-inflammatory effect on the pleural cavity of the mice and this effect seems to be primarily mediated via activation brady Kinin B2 receptors which trigger the release of other mediators.

Journal ArticleDOI
TL;DR: Data may indicate an involvement of 5-HT circuits in food intake as well as in water intake control systems in the pigeon, and that serotoninergic effects in these functional domains are mediated by independent mechanisms.