University of Connecticut

About: University of Connecticut is a education organization based out in Storrs, Connecticut, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 35297 authors who have published 81224 publications receiving 2952682 citations. The organization is also known as: UConn & Storrs Agricultural School.

A meta-analysis of the effect of mediated health communication campaigns on behavior change in the United States.

Abstract: A meta-analysis was performed of studies of mediated health campaigns in the United States in order to examine the effects of the campaigns on behavior change. Mediated health campaigns have small measurable effects in the short-term. Campaign effect sizes varied by the type of behavior: r¯ = .15 for seat belt use, r¯ = .13 for oral health, r¯ = .09 for alcohol use reduction, r¯ = .05 for heart disease prevention, r¯ = .05 for smoking, r¯ = .04 for mammography and cervical cancer screening, and r¯ = .04 for sexual behaviors. Campaigns with an enforcement component were more effective than those without. To predict campaign effect sizes for topics other than those listed above, researchers can take into account whether the behavior in a cessation campaign was addictive, and whether the campaign promoted the commencement of a new behavior, versus cessation of an old behavior, or prevention of a new undesirable behavior. Given the small campaign effect sizes, campaign planners should set modest goals for fut...

Fluorescent carbon dots and their sensing applications

Abstract: Fluorescent carbon dots (CDs) are a new class of carbon nanomaterials and have demonstrated excellent optical properties, good biocompatibility, great aqueous solubility, low cost, simple synthesis, etc. Since their discovery, various synthesis methods using different precursors have been developed, and are mainly classified as top-down and bottom-up approaches. For the mechanistic origin of CDs photoluminescence, three mechanisms have been proposed such as quantum confinement effect, surface state and molecule state. CDs have presented many applications, and this review article mainly focuses on the development of CDs based fluorescent sensors in recent 5 years. The sensing mechanisms, senor design and sensing properties to various targets are summarized. A broad range of analytes including cations, anions, small molecules, macromolecules, cells and bacteria have been discussed. In addition, the challenges and future directions for CDs as sensing materials are also presented.

The Questionnaire for Eudaimonic Well-Being: Psychometric properties, demographic comparisons, and evidence of validity

Abstract: The Questionnaire for Eudaimonic Well-Being (QEWB) was developed to measure well-being in a manner consistent with how it is conceptualized in eudaimonist philosophy. Aspects of eudaimonic well-being assessed by the QEWB include self-discovery, perceived development of one's best potentials, a sense of purpose and meaning in life, intense involvement in activities, investment of significant effort, and enjoyment of activities as personally expressive. The QEWB was administered to two large, ethnically diverse samples of college students drawn from multiple sites across the United States. A three-part evaluation of the instrument was conducted: (1) evaluating psychometric properties, (2) comparing QEWB scores across gender, age, ethnicity, family income, and family structure, and (3) assessing the convergent, discriminant, construct, and incremental validity of the QEWB. Six hypotheses relating QEWB scores to identity formation, personality traits, and positive and negative psychological functioning were evaluated. The internal consistency of the scale was high and results of independent CFAs indicated that the QEWB items patterned onto a common factor. The distribution of scores approximated a normal curve. Demographic variables were found to predict only small proportions of QEWB score variability. Support for the hypotheses tested provides evidence for the validity of the QEWB as an instrument for assessing eudaimonic well-being. Implications for theory and future research directions are discussed.

Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

Abstract: This critical review evaluates progress toward viable point-of-care protein biomarker measurements for cancer detection and diagnostics. The ability to measure panels of specific, selective cancer biomarker proteins in physicians' surgeries and clinics has the potential to revolutionize cancer detection, monitoring, and therapy. The dream envisions reliable, cheap, automated, technically undemanding devices that can analyze a patient's serum or saliva in a clinical setting, allowing on-the-spot diagnosis. Existing commercial products for protein assays are reliable in laboratory settings, but have limitations for point-of-care applications. A number of ultrasensitive immunosensors and some arrays have been developed, many based on nanotechnology. Multilabel detection coupled with high capture molecule density in immunosensors and arrays seems to be capable of detecting a wide range of protein concentrations with sensitivity ranging into the sub pg mL−1 level. Multilabel arrays can be designed to detect both high and ultralow abundance proteins in the same sample. However, only a few of the newer ultrasensitive methods have been evaluated with real patient samples, which is key to establishing clinical sensitivity and selectivity.