University of Connecticut

About: University of Connecticut is a education organization based out in Storrs, Connecticut, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 35297 authors who have published 81224 publications receiving 2952682 citations. The organization is also known as: UConn & Storrs Agricultural School.

A Review of the Biocompatibility of Implantable Devices: Current Challenges to Overcome Foreign Body Response:

Abstract: In recent years, a variety of devices (drug-eluting stents, artificial organs, biosensors, catheters, scaffolds for tissue engineering, heart valves, etc.) have been developed for implantation into patients. However, when such devices are implanted into the body, the body can react to these in a number of different ways. These reactions can result in an unexpected risk for patients. Therefore, it is important to assess and optimize the biocompatibility of implantable devices. To date, numerous strategies have been investigated to overcome body reactions induced by the implantation of devices. This review focuses on the foreign body response and the approaches that have been taken to overcome this. The biological response following device implantation and the methods for biocompatibility evaluation are summarized. Then the risks of implantable devices and the challenges to overcome these problems are introduced. Specifically, the challenges used to overcome the functional loss of glucose sensors, restenosis after stent implantation, and calcification induced by implantable devices are discussed.

Welfare-state decommodification in 18 OECD countries: a replication and revision:

Abstract: We present and discuss a replication and reassessment of the welfare-state decommodification index, and introduce a new, publicly available data set of key welfare-state programme characteristics Using the same programme features used to create the ‘decommodification index’ in The Three Worlds of Welfare Capitalism, one of the most widely cited sources in the field, we are able to replicate the results quite closely However, our investigation suggests a number of likely errors in the original formulation Once these are accounted for, we find very limited empirical support for the ‘three worlds’ typology in the decommodification data Though some clear differences remain, there is also much less overall variation among countries Furthermore, there is little evidence of ‘clustering’ among programme scores, a finding which is at odds with the idea of distinctive national regimes Our results point to the need for a detailed re-investigation of welfare-state benefits in advanced industrial democracies Ou

FIP/AAPS guidelines to dissolution/in vitro release testing of novel/special dosage forms

Abstract: Contributors Jean-Marc Aiache, Nobuo Aoyagi, Dennis Bashaw, Cynthia Brown, William Brown, Diane Burgess, John Crison, Patrick DeLuca, Ruzica Djerki, Jennifer Dressman, Thomas Foster, Kirsti Gjellan, Vivian Gray, Ajaz Hussain, Tom Ingallinera, James Klancke, Johannes Kraemer, Henning Kristensen, Kofi Kumi, Christian Leuner, Jobst Limberg, Petra Loos, Lenny Margulis, Patrick Marroum, Helga Moeller, Bernd Mueller, Martin Mueller-Zsigmondy, Ngozi Okafo, Larry Ouderkirk, Shravan Parsi, Saeed Qureshi, Joseph Robinson, Vinod Shah, Martin Siewert, Ramana Uppoor, and Roger Williams. Aventis, Frankfurt, Germany JW Goethe University, Frankfurt, Germany Eli Lilly and Company, Indianapolis, IN Office of Pharmaceutical Science, Center for Drug Evaluation and Research, US Food and Drug Administration, Rockville, MD Universite d'Auvergne, Clermont-Ferrand Cedex, France National Institute of Health Sciences, Division of Drugs, Tokyo, Japan US Pharmacopeia, Rockville, MD University of Connecticut, Storrs Mansfield, CT Pfizer, Inc, La Jolla, CA University of Kentucky, Lexington, KY Novartis Pharma, Basel, Switzerland AstraZeneca, Sodertalje, Sweden V.A. Gray Consulting, Inc, Hockessin, DE AAI International, Charleston, SC CIMA Laboratories, Inc, Minneapolis, MN Laboratory and Quality Services, Eschborn, Germany University of Copenhagen, Denmark Bundesinstitut fur Arzneimittel, Bonn, Germany Aventis Pharmaceuticals, Bridgewater, NJ Pfizer, Groton, CT Zentrallaboratorium Deutscher Apotheker, Eschborn, Germany Kiel University, Kiel, Germany Alza Corporation, Mountain View, CA DPT Laboratories, Ltd, San Antonio, TX Health Protection Branch, Ottawa, Canada University of Wisconsin, WI

From Opportunity Insight to Opportunity Intention: The Importance of Person‐Situation Learning Match

Abstract: Within the context of opportunity development as a learning process, this paper explores the intentionality that drives the early stages of this process, from the initial occurrence of an idea to its further exploration and elaboration by a potential entrepreneur. It establishes that the specific situations that induce opportunity insights also affect the roles that individuals' prior knowledge and learning approaches play for the formation of opportunity intentions. The likelihood of acting on their initial opportunity insights depends not only on how much prior knowledge individuals have of the opportunity domain, but also on whether their learning style matches the situation at hand. The results from an experiment show that domain-specific knowledge enables action when there is a person–situation match and impedes it when such a match is lacking.