Institution
University of Connecticut
Education•Storrs, Connecticut, United States•
About: University of Connecticut is a education organization based out in Storrs, Connecticut, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 35297 authors who have published 81224 publications receiving 2952682 citations. The organization is also known as: UConn & Storrs Agricultural School.
Papers published on a yearly basis
Papers
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TL;DR: It is confirmed that long-term heavy cannabis users show impairments in memory and attention that endure beyond the period of intoxication and worsen with increasing years of regular cannabis use.
Abstract: ContextCognitive impairments are associated with long-term cannabis use, but
the parameters of use that contribute to impairments and the nature and endurance
of cognitive dysfunction remain uncertain.ObjectiveTo examine the effects of duration of cannabis use on specific areas
of cognitive functioning among users seeking treatment for cannabis dependence.Design, Setting, and ParticipantsMultisite retrospective cross-sectional neuropsychological study conducted
in the United States (Seattle, Wash; Farmington, Conn; and Miami, Fla) between
1997 and 2000 among 102 near-daily cannabis users (51 long-term users: mean,
23.9 years of use; 51 shorter-term users: mean, 10.2 years of use) compared
with 33 nonuser controls.Main Outcome MeasuresMeasures from 9 standard neuropsychological tests that assessed attention,
memory, and executive functioning, and were administered prior to entry to
a treatment program and following a median 17-hour abstinence.ResultsLong-term cannabis users performed significantly less well than shorter-term
users and controls on tests of memory and attention. On the Rey Auditory Verbal
Learning Test, long-term users recalled significantly fewer words than either
shorter-term users (P = .001) or controls (P = .005); there was no difference between shorter-term
users and controls. Long-term users showed impaired learning (P = .007), retention (P = .003), and retrieval
(P = .002) compared with controls. Both user groups
performed poorly on a time estimation task (P<.001
vs controls). Performance measures often correlated significantly with the
duration of cannabis use, being worse with increasing years of use, but were
unrelated to withdrawal symptoms and persisted after controlling for recent
cannabis use and other drug use.ConclusionsThese results confirm that long-term heavy cannabis users show impairments
in memory and attention that endure beyond the period of intoxication and
worsen with increasing years of regular cannabis use.
751 citations
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03 May 2016
TL;DR: The SAGER guidelines are designed primarily to guide authors in preparing their manuscripts, but they are also useful for editors, as gatekeepers of science, to integrate assessment of sex and gender into all manuscripts as an integral part of the editorial process.
Abstract: Sex and gender differences are often overlooked in research design, study implementation and scientific reporting, as well as in general science communication. This oversight limits the generalizability of research findings and their applicability to clinical practice, in particular for women but also for men. This article describes the rationale for an international set of guidelines to encourage a more systematic approach to the reporting of sex and gender in research across disciplines. A panel of 13 experts representing nine countries developed the guidelines through a series of teleconferences, conference presentations and a 2-day workshop. An internet survey of 716 journal editors, scientists and other members of the international publishing community was conducted as well as a literature search on sex and gender policies in scientific publishing. The Sex and Gender Equity in Research (SAGER) guidelines are a comprehensive procedure for reporting of sex and gender information in study design, data analyses, results and interpretation of findings. The SAGER guidelines are designed primarily to guide authors in preparing their manuscripts, but they are also useful for editors, as gatekeepers of science, to integrate assessment of sex and gender into all manuscripts as an integral part of the editorial process.
751 citations
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TL;DR: Men treated for localized prostate cancer commonly had declines in all functional domains during 15 years of follow-up, and no significant relative differences in disease-specific functional outcomes were observed among men undergoing prostatectomy or radiotherapy.
Abstract: Background The purpose of this analysis was to compare long-term urinary, bowel, and sexual function after radical prostatectomy or external-beam radiation therapy. Methods The Prostate Cancer Outcomes Study (PCOS) enrolled 3533 men in whom prostate cancer had been diagnosed in 1994 or 1995. The current cohort comprised 1655 men in whom localized prostate cancer had been diagnosed between the ages of 55 and 74 years and who had undergone either surgery (1164 men) or radiotherapy (491 men). Functional status was assessed at baseline and at 2, 5, and 15 years after diagnosis. We used multivariable propensity scoring to compare functional outcomes according to treatment. Results Patients undergoing prostatectomy were more likely to have urinary incontinence than were those undergoing radiotherapy at 2 years (odds ratio, 6.22; 95% confidence interval [CI], 1.92 to 20.29) and 5 years (odds ratio, 5.10; 95% CI, 2.29 to 11.36). However, no significant between-group difference in the odds of urinary incontinence ...
750 citations
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TL;DR: In this article, it is shown that the fundamental crash process follows a Bernoulli trial with unequal probability of independent events, also known as Poisson trials, and that the Poisson and other mixed probabilistic structures are approximations assumed for modeling the motor vehicle crash process.
749 citations
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TL;DR: A framework for fitting multiple random walks to animal move- ment paths consisting of ordered sets of step lengths and turning angles, which allows for identification of different movement states using several properties of observed paths and lead naturally to the formulation of movement models.
Abstract: We present a framework for fitting multiple random walks to animal move- ment paths consisting of ordered sets of step lengths and turning angles. Each step and turn is assigned to one of a number of random walks, each characteristic of a different behavioral state. Behavioral state assignments may be inferred purely from movement data or may include the habitat type in which the animals are located. Switching between different behavioral states may be modeled explicitly using a state transition matrix estimated directly from data, or switching probabilities may take into account the proximity of animals to landscape features. Model fitting is undertaken within a Bayesian framework using the WinBUGS software. These methods allow for identification of different movement states using several properties of observed paths and lead naturally to the formulation of movement models. Analysis of relocation data from elk released in east-central Ontario, Canada, suggests a biphasic movement behavior: elk are either in an ''encamped'' state in which step lengths are small and turning angles are high, or in an ''exploratory'' state, in which daily step lengths are several kilometers and turning angles are small. Animals encamp in open habitat (agricultural fields and opened forest), but the exploratory state is not associated with any particular habitat type.
746 citations
Authors
Showing all 35666 results
Name | H-index | Papers | Citations |
---|---|---|---|
Zhong Lin Wang | 245 | 2529 | 259003 |
Richard A. Flavell | 231 | 1328 | 205119 |
Ralph Weissleder | 184 | 1160 | 142508 |
Eric J. Nestler | 178 | 748 | 116947 |
David L. Kaplan | 177 | 1944 | 146082 |
Masayuki Yamamoto | 171 | 1576 | 123028 |
Mark Gerstein | 168 | 751 | 149578 |
Marc A. Pfeffer | 166 | 765 | 133043 |
Carl W. Cotman | 165 | 809 | 105323 |
Murray F. Brennan | 161 | 925 | 97087 |
Alfred L. Goldberg | 156 | 474 | 88296 |
Xiang Zhang | 154 | 1733 | 117576 |
Hakon Hakonarson | 152 | 968 | 101604 |
Christopher P. Cannon | 151 | 1118 | 108906 |
James M. Wilson | 150 | 1010 | 78686 |