Institution
University of Illinois at Chicago
Education•Chicago, Illinois, United States•
About: University of Illinois at Chicago is a education organization based out in Chicago, Illinois, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 57071 authors who have published 110536 publications receiving 4264936 citations.
Topics: Population, Poison control, Health care, Cancer, Medicine
Papers published on a yearly basis
Papers
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TL;DR: The concept of urban computing is introduced, discussing its general framework and key challenges from the perspective of computer sciences, and the typical technologies that are needed in urban computing are summarized into four folds.
Abstract: Urbanization's rapid progress has modernized many people's lives but also engendered big issues, such as traffic congestion, energy consumption, and pollution. Urban computing aims to tackle these issues by using the data that has been generated in cities (e.g., traffic flow, human mobility, and geographical data). Urban computing connects urban sensing, data management, data analytics, and service providing into a recurrent process for an unobtrusive and continuous improvement of people's lives, city operation systems, and the environment. Urban computing is an interdisciplinary field where computer sciences meet conventional city-related fields, like transportation, civil engineering, environment, economy, ecology, and sociology in the context of urban spaces. This article first introduces the concept of urban computing, discussing its general framework and key challenges from the perspective of computer sciences. Second, we classify the applications of urban computing into seven categories, consisting of urban planning, transportation, the environment, energy, social, economy, and public safety and security, presenting representative scenarios in each category. Third, we summarize the typical technologies that are needed in urban computing into four folds, which are about urban sensing, urban data management, knowledge fusion across heterogeneous data, and urban data visualization. Finally, we give an outlook on the future of urban computing, suggesting a few research topics that are somehow missing in the community.
1,290 citations
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TL;DR: A developmentally sensitive, elaborated cognitive vulnerability-transactional stress model of depression is proposed to explain the "big fact" of the emergence of the gender difference in depression during adolescence.
Abstract: Descriptive epidemiological studies are reviewed, showing that the female preponderance in depression begins to emerge around age 13. A developmentally sensitive, elaborated cognitive vulnerability-transactional stress model of depression is proposed to explain the "big fact" of the emergence of the gender difference in depression. The elaborated causal chain posits that negative events contribute to initial elevations of general negative affect. Generic cognitive vulnerability factors then moderate the likelihood that the initial negative affect will progress to full-blown depression. Increases in depression can lead transactionally to more self-generated dependent negative life events and thus begin the causal chain again. Evidence is reviewed providing preliminary support for the model as an explanation for the development of the gender difference in depression during adolescence.
1,271 citations
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TL;DR: This update article presents a list of plant-derived drugs, with the names of the plant sources, and their actions or uses in therapy.
Abstract: One of the prerequisites for the success of primary health care is the availability and use of suitable drugs. Plants have always been a common source of medicaments, either in the form of traditional preparations or as pure active principles. It is thus reasonable for decision-makers to identify locally available plants or plant extracts that could usefully be added to the national list of drugs, or that could even replace some pharmaceutical preparations that need to be purchased and imported. This update article presents a list of plant-derived drugs, with the names of the plant sources, and their actions or uses in therapy.
1,270 citations
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TL;DR: From this phylogenetic orientation, the polyvagal theory proposes a biological basis for social behavior and an intervention strategy to enhance positive social behavior.
1,266 citations
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TL;DR: In vitro results support evidence that ERK-phosphorylated MLCK has an increased capacity to phosphorylate MLC and shows increased sensitivity to calmodulin, and define a signaling pathway directly downstream of MAP kinase, influencing cell migration on the extracellular matrix.
Abstract: Cell interaction with adhesive proteins or growth factors in the extracellular matrix initiates Ras/ mitogen-activated protein (MAP) kinase signaling. Evidence is provided that MAP kinase (ERK1 and ERK2) influences the cells' motility machinery by phosphorylating and, thereby, enhancing myosin light chain kinase (MLCK) activity leading to phosphorylation of myosin light chains (MLC). Inhibition of MAP kinase activity causes decreased MLCK function, MLC phosphorylation, and cell migration on extracellular matrix proteins. In contrast, expression of mutationally active MAP kinase kinase causes activation of MAP kinase leading to phosphorylation of MLCK and MLC and enhanced cell migration. In vitro results support these findings since ERK-phosphorylated MLCK has an increased capacity to phosphorylate MLC and shows increased sensitivity to calmodulin. Thus, we define a signaling pathway directly downstream of MAP kinase, influencing cell migration on the extracellular matrix.
1,265 citations
Authors
Showing all 57433 results
Name | H-index | Papers | Citations |
---|---|---|---|
Meir J. Stampfer | 277 | 1414 | 283776 |
Frank B. Hu | 250 | 1675 | 253464 |
Lewis C. Cantley | 196 | 748 | 169037 |
Ronald Klein | 194 | 1305 | 149140 |
Anil K. Jain | 183 | 1016 | 192151 |
Yusuke Nakamura | 179 | 2076 | 160313 |
Bruce M. Spiegelman | 179 | 434 | 158009 |
Jie Zhang | 178 | 4857 | 221720 |
D. M. Strom | 176 | 3167 | 194314 |
Yury Gogotsi | 171 | 956 | 144520 |
Todd R. Golub | 164 | 422 | 201457 |
Rodney S. Ruoff | 164 | 666 | 194902 |
Philip A. Wolf | 163 | 459 | 114951 |
Barbara E.K. Klein | 160 | 856 | 93319 |
David Jonathan Hofman | 159 | 1407 | 140442 |