University of Illinois at Chicago

About: University of Illinois at Chicago is a education organization based out in Chicago, Illinois, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 57071 authors who have published 110536 publications receiving 4264936 citations.

Danger Zone Entrepreneurs: The Importance of Resilience and Self‐Efficacy for Entrepreneurial Intentions

Abstract: Little is known about the drivers of entrepreneurial decisions during war. We empirically examine the effects of perceived danger, entrepreneurial self-efficacy, and resilience on entrepreneurial intentions in adverse conditions with primary survey data from Afghanistan. Our findings suggest that perceived danger is negatively related to an individual's entrepreneurial intentions, but marginally less so among highly resilient individuals. Our findings also suggest that even under conditions of war, individuals develop entrepreneurial intentions if they are able to grow from adversity (resilience) and believe in their entrepreneurial abilities (entrepreneurial self-efficacy). Practical implications for role modeling and entrepreneurship training are then discussed.

TFOS DEWS II Report Executive Summary

Abstract: This article presents an Executive Summary of the conclusions and recommendations of the 10-chapter TFOS DEWS II report. The entire TFOS DEWS II report was published in the July 2017 issue of The Ocular Surface. A downloadable version of the document and additional material, including videos of diagnostic and management techniques, are available on the TFOS website: www.TearFilm.org.

Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator.

Abstract: The immunoglobulin light-chain gene enhancers E kappa 3', E lambda 2-4, and E lambda 3-1 contain a conserved cell type-specific composite element essential for their activities. This element binds a B cell-specific heterodimeric protein complex that consists of the Ets family member PU.1 and a second factor (NF-EM5), whose participation in the formation of the complex is dependent on the presence of DNA-bound PU.1. In this report we describe the cloning and characterization of Pip (PU.1 interaction partner), a lymphoid-specific protein that is most likely NF-EM5. As expected, the Pip protein binds the composite element only in the presence of PU.1; furthermore, the formation of this ternary complex is critically dependent on phosphorylation of PU.1 at serine-148. The Pip gene is expressed specifically in lymphoid tissues in both B- and T-cell lines. When coexpressed in NIH-3T3 cells, Pip and PU.1 function as mutually dependent transcription activators of the composite element. The amino-terminal DNA-binding domain of Pip exhibits a high degree of homology to the DNA-binding domains of members of the interferon regulatory factor (IRF) family, which includes IRF-1, IRF-2, ICSBP, and ISGF3 gamma.

Structural covariates of u.s. county homicide rates: incorporating spatial effects*

Abstract: Spatial analysis is statistically and substantively important for macrolevel criminological inquiry. Using county-level data for the decennial years in the 1960 to 1990 time period, we reexamine the impact of conventional structural covariates on homicide rates and explicitly model spatial effects. Important findings are: (1) homicide is strongly clustered in space; (2) this clustering cannot be completely explained by common measures of the structural similarity of neighboring counties; (3) noteworthy regional differences are observed in the effects of structural covariates on homicide rates; and (4) evidence consistent with a diffusion process for homicide is observed in the South throughout the 1960–1990 period.