Institution
University of North Carolina at Chapel Hill
Education•Chapel Hill, North Carolina, United States•
About: University of North Carolina at Chapel Hill is a education organization based out in Chapel Hill, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 81393 authors who have published 185327 publications receiving 9948508 citations. The organization is also known as: University of North Carolina & North Carolina.
Topics: Population, Poison control, Health care, Cancer, Medicine
Papers published on a yearly basis
Papers
More filters
••
Benjamin F. Voight1, Benjamin F. Voight2, Laura J. Scott3, Valgerdur Steinthorsdottir4 +180 more•Institutions (53)
TL;DR: By combining genome-wide association data from 8,130 individuals with type 2 diabetes and 38,987 controls of European descent and following up previously unidentified meta-analysis signals, 12 new T2D association signals are identified with combined P < 5 × 10−8.
Abstract: By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D) and 38,987 controls of European descent and following up previously unidentified meta-analysis signals in a further 34,412 cases and 59,925 controls, we identified 12 new T2D association signals with combined P<5x10(-8). These include a second independent signal at the KCNQ1 locus; the first report, to our knowledge, of an X-chromosomal association (near DUSP9); and a further instance of overlap between loci implicated in monogenic and multifactorial forms of diabetes (at HNF1A). The identified loci affect both beta-cell function and insulin action, and, overall, T2D association signals show evidence of enrichment for genes involved in cell cycle regulation. We also show that a high proportion of T2D susceptibility loci harbor independent association signals influencing apparently unrelated complex traits.
1,785 citations
••
TL;DR: In this paper, the authors contribute to the emerging body of knowledge on buyer-seller relationships in business markets, focusing on the relationship between buyers and sellers in the context of marketing managers and scholars.
Abstract: During the past decade, marketing managers and scholars have focused increased attention on buyer–seller relationships in business markets. This article contributes to the emerging body of knowledg...
1,783 citations
••
TL;DR: Although still at a very early stage of development, NMOFs have already shown great promise as a novel platform for nanomedicine and should allow for the incorporation of other imaging and therapeutic agents and their effective delivery to targeted cells in vivo.
Abstract: Metal–organic frameworks (MOFs), a class of hybrid materials formed by the self-assembly of polydentate bridging ligands and metal-connecting points, have been studied for a variety of applications. Recently, these materials have been scaled down to nanometer sizes, and this Account details the development of nanoscale metal–organic frameworks (NMOFs) for biomedical applications. NMOFs possess several potential advantages over conventional nanomedicines such as their structural and chemical diversity, their high loading capacity, and their intrinsic biodegradability. Under relatively mild conditions, NMOFs can be obtained as either crystalline or amorphous materials. The particle composition, size, and morphology can be easily tuned to optimize the final particle properties. Researchers have employed two general strategies to deliver active agents using NMOFs: by incorporating active agents into the frameworks or by loading active agents into the pores and channels of the NMOFs. The modification of NMOF s...
1,780 citations
••
TL;DR: In this article, a short introduction to cyclic voltammetry is provided to help the reader with data acquisition and interpretation, and common pitfalls are provided, and the reader is encouraged to apply what is learned in short, simple training modules provided in the Supporting Information.
Abstract: Despite the growing popularity of cyclic voltammetry, many students do not receive formalized training in this technique as part of their coursework. Confronted with self-instruction, students can be left wondering where to start. Here, a short introduction to cyclic voltammetry is provided to help the reader with data acquisition and interpretation. Tips and common pitfalls are provided, and the reader is encouraged to apply what is learned in short, simple training modules provided in the Supporting Information. Armed with the basics, the motivated aspiring electrochemist will find existing resources more accessible and will progress much faster in the understanding of cyclic voltammetry.
1,779 citations
••
TL;DR: The mean size of the gold core in the synthesis of dodecanethiolate-stabilized Au cluster compounds can be finely adjusted by choice of the Au:dodecanETHiolate ratio and the temperature and rate at which the reduction is conducted as mentioned in this paper.
Abstract: The mean size of the gold (Au) core in the synthesis of dodecanethiolate-stabilized Au cluster compounds can be finely adjusted by choice of the Au:dodecanethiolate ratio and the temperature and rate at which the reduction is conducted. The Au clusters have been examined with a large number of independent analytical tools, producing a remarkably consistent picture of these materials. Average cluster and core dimensions, as ascertained by 1H NMR line broadening, high-resolution transmission electron microscopy, small-angle X-ray scattering, and thermogravimetric analysis, vary between diameters of 1.5 and 5.2 nm (∼110−4800 Au atoms/core). The electronic properties of the Au core were examined by UV/vis and X-ray photoelectron spectroscopy; the core appears to remain largely metallic in nature even at the smallest core sizes examined. The alkanethiolate monolayer stabilizing the Au core ranges with core size from ∼53 to nearly 520 ligands/core, and was probed by Fourier transform infrared spectroscopy, diff...
1,778 citations
Authors
Showing all 82249 results
Name | H-index | Papers | Citations |
---|---|---|---|
Walter C. Willett | 334 | 2399 | 413322 |
Salim Yusuf | 231 | 1439 | 252912 |
David J. Hunter | 213 | 1836 | 207050 |
Irving L. Weissman | 201 | 1141 | 172504 |
Eric J. Topol | 193 | 1373 | 151025 |
Dennis W. Dickson | 191 | 1243 | 148488 |
Scott M. Grundy | 187 | 841 | 231821 |
Peidong Yang | 183 | 562 | 144351 |
Patrick O. Brown | 183 | 755 | 200985 |
Eric Boerwinkle | 183 | 1321 | 170971 |
Alan C. Evans | 183 | 866 | 134642 |
Anil K. Jain | 183 | 1016 | 192151 |
Terrie E. Moffitt | 182 | 594 | 150609 |
Aaron R. Folsom | 181 | 1118 | 134044 |
Valentin Fuster | 179 | 1462 | 185164 |