University of Nottingham

About: University of Nottingham is a education organization based out in Nottingham, Nottingham, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 54772 authors who have published 119600 publications receiving 4227408 citations. The organization is also known as: The University of Nottingham & University College, Nottingham.

The dark energy survey data release 1

Abstract: We describe the first public data release of the Dark Energy Survey, DES DR1, consisting of reduced single-epoch images, co-added images, co-added source catalogs, and associated products and services assembled over the first 3 yr of DES science operations. DES DR1 is based on optical/near-infrared imaging from 345 distinct nights (2013 August to 2016 February) by the Dark Energy Camera mounted on the 4 m Blanco telescope at the Cerro Tololo InterAmerican Observatory in Chile. We release data from the DES wide-area survey covering similar to 5000 deg(2) of the southern Galactic cap in five broad photometric bands, grizY. DES DR1 has a median delivered point-spread function of g = 1.12, r = 0.96, i = 0.88, z = 0.84, and Y = 0.'' 90 FWHM, a photometric precision of <1% in all bands, and an astrometric precision of 151 mas. The median co-added catalog depth for a 1.'' 95 diameter aperture at signal-to-noise ratio (S/N) = 10 is g = 24.33, r = 24.08, i = 23.44, z = 22.69, and Y = 21.44 mag. DES DR1 includes nearly 400 million distinct astronomical objects detected in similar to 10,000 co-add tiles of size 0.534 deg(2) produced from similar to 39,000 individual exposures. Benchmark galaxy and stellar samples contain similar to 310 million and similar to 80 million objects, respectively, following a basic object quality selection. These data are accessible through a range of interfaces, including query web clients, image cutout servers, jupyter notebooks, and an interactive co-add image visualization tool. DES DR1 constitutes the largest photometric data set to date at the achieved depth and photometric precision.

A transverse shear deformation theory for homogeneous monoclinic plates

Abstract: A general two-dimensional theory suitable for the static and/or dynamic analysis of a transverse shear deformable plate, constructed of a homogeneous, monoclinic, linearly elastic material and subjected to any type of shear tractions at its lateral planes, is presented. Developed on the basis of Hamilton's principle, in conjunction with the method of Lagrange multipliers, this new theory accounts for an unlimited number of choices of through-thickness displacement distributions, while, starting with the smallest possible number of independent displacement components (five, for a shear deformation theory), it is capable of further operating with as many degrees of freedom as desired. For the particular case of a theory operating with five degrees of freedom, special attention is given to displacement expansions producing symmetric, through thicknes, distributions of transverse shear strain. For the cylindrical bending problem of a specially orthotropic plate, the governing equations of that five-degrees-of-freedom theory are solved and for three different choices of symmetric, through tickness, transverse shear deformation, numerical results are obtained and compared with corresponding results based on the exact three-dimensional solution existing in the literature. The comparisons made show clearly, that the multiple options offered by the new theory, by either suitably altering the displacement expansions or gradually increasing the degrees of freedom involved, will be found useful in future studies dealing with the static and/or dynamic analysis of homogeneous plates.

Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels

Abstract: Fabrication of three dimensional (3D) organoids with controlled microarchitectures has been shown to enhance tissue functionality. Bioprinting can be used to precisely position cells and cell-laden materials to generate controlled tissue architecture. Therefore, it represents an exciting alternative for organ fabrication. Despite the rapid progress in the field, the development of printing processes that can be used to fabricate macroscale tissue constructs from ECM-derived hydrogels has remained a challenge. Here we report a strategy for bioprinting of photolabile cell-laden methacrylated gelatin (GelMA) hydrogels. We bioprinted cell-laden GelMA at concentrations ranging from 7 to 15% with varying cell densities and found a direct correlation between printability and the hydrogel mechanical properties. Furthermore, encapsulated HepG2 cells preserved cell viability for at least eight days following the bioprinting process. In summary, this work presents a strategy for direct-write bioprinting of a cell-laden photolabile ECM-derived hydrogel, which may find widespread application for tissue engineering, organ printing and the development of 3D drug discovery platforms.