Institution
University of Texas System
Education•Austin, Texas, United States•
About: University of Texas System is a education organization based out in Austin, Texas, United States. It is known for research contribution in the topics: Cancer & Population. The organization has 13901 authors who have published 10925 publications receiving 319328 citations. The organization is also known as: UT System.
Topics: Cancer, Population, Antigen, Gene, Antibody
Papers published on a yearly basis
Papers
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TL;DR: Design of MAIQ-1, a derivative of this class with strong inhibitory potency for ribonucleoside diphosphate reductase activity, as well as the other necessary requisite properties for clinical trial as an antineoplastic agent is proposed.
119 citations
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16 Jul 1992TL;DR: In this article, a solution of a single polylactide enantiomer is gelled to produce solid materials, or may be extracted with a nonsolvent prior to drying to make microporous materials.
Abstract: Resorbable materials and their preparation based on gelling a solution of a single polylactide enantiomer. The gel may be dried to produce solid materials, or may be extracted with a nonsolvent prior to drying to make microporous materials. Physical and mechanical properties of the material may be varied by varying the molecular weight of the gelling polymer, or by blending the gelling solution with other polymers or fillers. The resorbable materials can be used to make biodegradable implantation devices.
119 citations
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16 Apr 1997TL;DR: In this paper, the authors describe a new approach to three-dimensional molecular tailoring of surfaces, in which a plasma deposition step is initially employed to deposit reactive functional groups on the surface of a solid substrate, then immersion of the coated substrate in a solution during which time solute molecules react with the functional surface groups introduced during the plasma process.
Abstract: This invention describes a new approach to three-dimensional molecular tailoring of surfaces. In this process, a plasma deposition step is initally employed to deposit reactive functional groups on the surface of a solid substrate. This is then followed by immersion of the coated substrate in a solution during which time solute molecules react with the functional surface groups introduced during the plasma process. Solute molecules are attached to the surface during this second step. This simple two-step process is of general utility in that both the nature of the plasma introduced surface group and the nature of the solute molecules can be varied. Additionally it is possible to provide exact control of the surface density of reactive groups introduced during the plasma process and thus the concentration of solute molecules coupled to the solid surfaces. A particularly significant aspect of this invention is that the second step chemical derivatization reactions can be carried out using aqueous solutions at room temperature. The RF plasma polymerization of substituted perfluorohexenes is shown to produce films having unusually high -CF3 content. These films are produced under both pulsed and continuous-wave plasma deposition conditions. The relative -CF3 content of these polymers increases with decreasing average RF power absorbed during the film formation processes. The films produced under the least energetic condition (i.e., pulsed plasma, 0.1 ms on/3.0 ms off and 100 watts peak power) are exceptionally hydrophobic, exhibiting advancing and receding water contact angles in excess of those observed with Teflon® surfaces. The most hydrophobic films have a -CF3 content which represents 40 % of the carbon atoms present in the sample.
119 citations
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TL;DR: It is demonstrated that nuclear matrices prepared from the yeast Saccharomyces cerevisiae will specifically bind an MAR sequence derived from the mouse kappa light chain immunoglobulin gene, suggesting that both MAR sequences and their binding sites have been strongly evolutionarily conserved.
119 citations
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TL;DR: A combined method of S1 nuclease protection and polymerase chain reaction is used to amplified sequences representative of the chimeric bcr/abl transcripts, which have the potential to identify a subpopulation of Ph1-positive CML patients in remission who are at high risk of relapse.
119 citations
Authors
Showing all 13902 results
Name | H-index | Papers | Citations |
---|---|---|---|
Yi Chen | 217 | 4342 | 293080 |
Joseph L. Goldstein | 207 | 556 | 149527 |
Eric N. Olson | 206 | 814 | 144586 |
Hagop M. Kantarjian | 204 | 3708 | 210208 |
Thomas C. Südhof | 191 | 653 | 118007 |
Gordon B. Mills | 187 | 1273 | 186451 |
Michael S. Brown | 185 | 422 | 123723 |
Eric Boerwinkle | 183 | 1321 | 170971 |
Russel J. Reiter | 169 | 1646 | 121010 |
John D. Minna | 169 | 951 | 106363 |
Timothy A. Springer | 167 | 669 | 122421 |
Gabriel N. Hortobagyi | 166 | 1374 | 104845 |
Rodney S. Ruoff | 164 | 666 | 194902 |
Ralph A. DeFronzo | 160 | 759 | 132993 |
Ronald A. DePinho | 160 | 486 | 104039 |