University of Texas System

About: University of Texas System is a education organization based out in Austin, Texas, United States. It is known for research contribution in the topics: Cancer & Population. The organization has 13901 authors who have published 10925 publications receiving 319328 citations. The organization is also known as: UT System.

Photovoltaic devices based on nanostructured polymer films molded from porous template

Abstract: The present invention includes a template, an optoelectronic device and methods for making the same. The optoelectronic device includes a first substrate; a first electrode disposed on the first substrate; a first interdigitating, nano-structured charge-transfer molded material (e.g., a polymer) with a first electron affinity disposed on the first electrode; a second interdigitating, nano-structured charge-transfer material (e.g., single molecules, quantum dots, or particles) with a second electron affinity disposed on the first interdigitating, nano-structured charge-transfer material; a second electrode disposed in the second interdigitating, nano-structured charge-transfer material; and a second substrate disposed on the second electrode.

Biphasic effect of estrogen on the sensitivity of the pituitary to luteinizing hormone-releasing factor (LRF).

Abstract: Infusions of synthetic LRF were given in ovariectomized animals, and the effect on plasma concentrations of FSH and LH was determined by radioimmunoassay. Synthetic LRF induced a graded release of LH between doses of 100-2500 ng⁄hr and of FSH with doses of 100 and 500 ng⁄hr of the decapeptide. Peak concentrations were reached at 2 hr in the case of LH and 3 hr in the case of FSH. The relative magnitude of the release of LH was much greater than the magnitude of FSH release. Intravenous injection of 100 ng of estradiol benzoate partially blocked the LH and FSH response to LRF within 1 hr following injection. The inhibitory effect was maximal at 2 hr and had largely disappeared by 4 hr. Injections of 50 or 200 ng of progesterone iv did not modify the responses to LRF infusion. If the infusion of LRF was delayed until 6 hr after the injection of estradiol benzoate, the pattern changed, and there was an enhanced response to LRF, such that plasma LH concentrations were 2½-fold greater in estradiol-treated anim...

Skeletogenesis in the sea urchin embryo.

Abstract: Skeletogenesis, a key morphogenetic event in the embryonic development of vertebrates, is also a very important, albeit a transient, milestone in the development of a marine invertebrate, the sea urchin. In recent years this biological system, in which the biomineralization process can be investigated in a well-defined, single cell type (the primary mesenchyme cell), has received considerable study. The objective of this review is to summarize our current knowledge about skeletogenesis in the sea urchin embryo and highlight the outstanding questions that remain to be answered. It will become apparent that there are two broad sets of questions: one set pertains to cell differentiation and morphogenesis; the other is concerned with basic cellular processes that are common to most cell types in a developing organism, such as cell-cell interactions, membrane fusion, ion transport and exocytosis. The former set of questions has been reviewed on numerous occasions, most recently by Morrill & Santos, 1985; Davidson, 1986; Solursh, 1986; Wilt, 1987'and McClay & Ettensohn, 1987. Therefore, coverage of these issues will be restricted to points that pertain to the basic cellular processes involved in spiculogenesis.

Telehealth-Enabled Emergency Medical Services Program Reduces Ambulance Transport to Urban Emergency Departments.

Abstract: Background Emergency medical services (EMS) agencies transport a significant majority of patients with low acuity and non-emergent conditions to local emergency departments (ED), affecting the entire emergency care system’s capacity and performance Opportunities exist for alternative models that integrate technology, telehealth, and more appropriately aligned patient navigation While a limited number of programs have evolved recently, no empirical evidence exists for their efficacy This research describes the development and comparative effectiveness of one large urban program Methods “Blinded for Peer Review” EMS initiated the Emergency Telehealth and Navigation (ETHAN) program in 2014 ETHAN combines telehealth, social services, and alternative transportation to navigate primary care related patients away from the ED where possible Using a case-control study design with multiple outcome variables, we describe the program and compare differences in effectiveness measures relative to the control group Results During the first 12 months, 5,570 patients received the intervention We found a 76% decrease in ambulance transports to the ED with the intervention (18% vs 74%, P<001) EMS productivity (median time from EMS notification to unit back in service) was 44 minutes faster for the ETHAN group (39 vs 83 minutes, median) There were no statistically significant differences in mortality or patient satisfaction Conclusions We found that mobile technology-driven delivery models are effective at reducing unnecessary ED ambulance transports and increasing EMS unit productivity This provides support for broader EMS mobile integrated health programs in other regions

Transport of LRF from CSF to Hypophysial Portal and Systemic Blood and the Release of LH

Abstract: The capacity of the median eminence to transport LRF from CSF to hypophysial portal blood and the efficacy of intraventricularly and intravenously administered LRF in releasing LH were studied. Ten to 15 min after 125 ng LRF was injected intraventricularly, LRF was detected in portal blood. The maximal rate of transport ranged from 35 to more than 200 pg'min. The rates of transport were much less following the administration of 25 or 5 ng LRF. When these same quantities of LRF were injected intraventricularly into rats with intact pituitary glands, plasma LH levels increased in proportion to the dose of LRF. The releasing action of LRF was long, and 120 min after the administration of 125 ng LRF, the concentration of plasma LH was 40- to 50-fold greater than the control level. Intravenous injection of 5, 25, or 125 ng LRF caused corresponding increases in LH release. Intravenously administered LRF stimulated LH release slightly faster than did LRF given intraventricularly, but the effect of intraventricul...