Institution
University of Texas System
Education•Austin, Texas, United States•
About: University of Texas System is a education organization based out in Austin, Texas, United States. It is known for research contribution in the topics: Cancer & Population. The organization has 13901 authors who have published 10925 publications receiving 319328 citations. The organization is also known as: UT System.
Topics: Cancer, Population, Antigen, Gene, Antibody
Papers published on a yearly basis
Papers
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TL;DR: It is indicated that upper esophageal sphincter corresponds mainly to the cricopharyngeus and inferior pharyngeal constrictor and the opening of the lower esophages is attributable to inhibition of the contraction of thecricopharyngus and superior pharynx and the forward displacement of the larynx by the geniohyoid muscle.
166 citations
Patent•
23 Apr 1997TL;DR: In this article, the use of poly(vinyl N-heterocycle)-block poly(alkylene oxide) copolymers in micelle containing pharmaceutical formulations is described.
Abstract: The present invention relates to the use of poly(vinyl N-heterocycle)-block-poly(alkylene oxide) copolymers in micelle containing pharmaceutical formulations. The copolymers advantageously respond to pH differences in the environment to which they are exposed forming micelles at higher pH values. The micelles, which comprise a therapeutic compound and a copolymer, deliver drug in a pH dependent manner.
166 citations
TL;DR: Primary hypopituitarism due to a hypothalamic lesion after radiotherapy for nasopharyngeal cancer may be more common than suspected and primary hypothyroidism may result from irradiation of regional neck nodes.
Abstract: Endocrine complications after radiotherapy for tumors of the head and neck are thought to be relatively rare. The availability of synthetic hypothalamic hormones for clinical investigations and the radioimmunoassay of hormones have enabled us to study function of the hypothalamic pituitary axis in 15 patients who had radiotherapy for nasopharyngeal cancer. Fourteen had evidence of endocrine deficiency. Twelve patients had evidence of hypothalamic dysfunction, 7 developed primary pituitary hormone deficiencies, and 3 developed primary hypothyroidism. These results indicate that [1] secondary hypopituitarism due to a hypothalamic lesion after radiotherapy for nasopharyngeal cancer may be more common than suspected in the past; [2] primary hypopituitarism after irradiation of extracranial tumors can occur; and [3[ primary hypothyroidism may result from irradiation of regional neck nodes.
165 citations
TL;DR: Combined chemotherapy with these agents is effective in increasing the CR rate and survival in patients with diffuse histiocytic lymphoma, and further observation will be needed to assess the effect of this combination on survival.
165 citations
TL;DR: The best prognostic immunological test was the patients' in-vitro lymphocyte blastogenic reactivity to autologous remission bone-marrow cells: all five patients who reacted vigorously have relapsed compared with none of the six who failed to react or reacted weakly.
165 citations
Authors
Showing all 13902 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Yi Chen | 217 | 4342 | 293080 |
| Joseph L. Goldstein | 207 | 556 | 149527 |
| Eric N. Olson | 206 | 814 | 144586 |
| Hagop M. Kantarjian | 204 | 3708 | 210208 |
| Thomas C. Südhof | 191 | 653 | 118007 |
| Gordon B. Mills | 187 | 1273 | 186451 |
| Michael S. Brown | 185 | 422 | 123723 |
| Eric Boerwinkle | 183 | 1321 | 170971 |
| Russel J. Reiter | 169 | 1646 | 121010 |
| John D. Minna | 169 | 951 | 106363 |
| Timothy A. Springer | 167 | 669 | 122421 |
| Gabriel N. Hortobagyi | 166 | 1374 | 104845 |
| Rodney S. Ruoff | 164 | 666 | 194902 |
| Ralph A. DeFronzo | 160 | 759 | 132993 |
| Ronald A. DePinho | 160 | 486 | 104039 |