University of the Philippines

About: University of the Philippines is a education organization based out in Quezon City, Philippines. It is known for research contribution in the topics: Population & Health care. The organization has 4589 authors who have published 4437 publications receiving 114846 citations. The organization is also known as: UP.

Topical corticosteroids as adjunctive therapy for bacterial keratitis

Abstract: Background Bacterial keratitis is a serious ocular infectious disease that can lead to severe visual disability. Risk factors for bacterial corneal infection include contact lens wear, ocular surface disease, corneal trauma, and previous ocular or eyelid surgery. Topical antibiotics constitute the mainstay of treatment in cases of bacterial keratitis, whereas the use of topical corticosteroids as an adjunctive therapy to antibiotics remains controversial. Topical corticosteroids are usually used to control inflammation using the smallest amount of the drug. Their use requires optimal timing, concomitant antibiotics, and careful follow-up.

Economic Burden of the Inadequate Management of Allergic Rhinitis and Urticaria in Asian Countries Based on the GA2LEN Model

Abstract: PURPOSE Across Hong Kong, Malaysia, the Philippines, Singapore, Thailand and Vietnam, (referred to as Asia) approximately 30-53 million individuals of the 151 million employed suffer from allergic rhinitis (AR) and urticaria. It is estimated that approximately 90% of patients with these allergic conditions are insufficiently treated, impacting the socioeconomic burden in terms of absence from work and decreased productivity. This study aims to estimate the socioeconomic burden of allergies in Asia and the cost savings that their adequate management can provide. Due to the limited availability of regional data, this study focused AR and urticaria in selected countries. METHODS Published literature, information from statistical bureaus, clinician surveys and extrapolation of selected data from the European Union were used to determine the socioeconomic costs of AR and urticaria. RESULTS Many patients in Asia suffer from perennial allergies and experience symptoms of AR and urticaria for up to 298 days per year. An estimate of the indirect costs of patients insufficiently treated for AR and urticaria amounts to USD 105.4 billion a year, which equates to USD 1,137-2,195 per patient due to absenteeism and presenteeism. Adherence to guideline-approved treatment can lead to estimated savings of up to USD 104 billion. CONCLUSIONS The current study suggests that within Asia, the socioeconomic impact of AR and urticaria is similar to that seen in the European Union in spite of the lower wages in Asia. This is due to the mainly perennial allergens prevailing in Asia, whereas the sensitization patterns observed in the European Union are dominated by seasonal exposure to pollen. These results underline the need for governmental initiatives to increase public awareness on the prevention and treatment of these and other allergic diseases as well as greater research funding and large-scale studies to reduce their growing socioeconomic burden in coming years.

Enhancing the food security of upland farming households through agroforestry in Claveria, Misamis Oriental, Philippines

Abstract: The impact of agroforestry on food security of upland farmers is least recognized and appreciated given that the linkage between them is quite complex and not well understood. The crucial role of agroforestry in enhancing food supply and augmenting family income is commonly ignored. This study aimed to get a deeper understanding of the role of agroforestry in ensuring food security of farming households in the Philippine uplands. A combination of participatory approaches including participatory rural appraisal, household survey, focused group discussions, field experiments and simulation modeling were used for the study conducted in Claveria, Northern Mindanao, Philippines. The first major finding was that the prime responsibility for ensuring adequacy of food production and supply for the farming households rested on the husband and wife. The second major finding based on the simulation results was that agroforestry increased and stabilized corn yields under hedgerow system. Moreover, fruits from perennial crops and trees served as secondary food crops especially during lean months of food supply. The last major finding was that the adoption of agroforestry significantly increased the level of benefits by around 42–137%, compared with the low income from continuous annual monocropping. The key to making upland farm households food secure is to increase the productivity of their farms and home gardens. A good start is to promote the agroforestry system in upland areas, and it is thereby recommended that both national and local government units mainstream their policies and efforts toward promotion of agroforestry adoption in the Philippine uplands.

Development of quantitative perimetric tests.

Abstract: A simple quantitative perimetric test which allows the investigator to differentiate inner retinal from outer retinal, and choroidal involvement at different points of the visual field, has been described. These studies of neural data processing (or interactive properties) are believed to reflect retinal receptive field properties. When studying receptive field properties in patients with optic nerve and visual pathway lesions, added variables tended to cause artifacts during measurement. Careful investigation of these patients has led to the definition of two time-varying factors, short-term fatigue and/or a saturation-like effect, and alteration in local adaptation. These factors should be studied in depth, particularly when investigating lesions occurring central to the retina. Two very simple tets for the purpose requiring only standard equipment have been described.

Allozyme electrophoresis as a tool for distinguishing different zooxanthellae symbiotic with giant clams

Abstract: The taxonomy of zooxanthellae in marine invertebrate symbioses is not well understood owing mainly to their lack of reliable morphological differences. Nevertheless, previous work using protein and DNA electrophoreses has set the stage for advancing our taxonomic understanding of cnidarian zooxanthellae. Here we present the use of allozymes as genetic markers for distinguishing algal isolates from tridacnid hosts. Zooxanthellae from seven Tridacna and Hippopus species were isolated and maintained in axenic clonal cultures over many generations. Of 16 enzyme systems, α- and β-esterase (EST), esterase-F (EST-F), glucose phosphate isomerase (GPI), and malate dehydrogenase (MDH) were found suitable polymorphic markers of genetic differences among clonal cultures. Of 39 clonal isolates, 97% were found to be genetically distinguishable. This high extent of genetic variation in zooxanthellae within and between clam species was unexpected, and is difficult to explain based solely on the general notion of asexual reproduction in symbiotic zooxanthellae. Our results are also consistent with the occurrence of sexual reproduction in clam zooxanthellae. The close genetic similarity of the symbionts of Tridacna gigas, the largest and fastest-growing clam species, and the difficulty of initiating their clonal cultures in the given nutrient medium, compared with the symbionts of other clam species, are further indicative of possibly distinct algal symbionts in T. gigas. These findings are discussed in light of current taxonomic understanding of these organisms.