Institution
University of the Philippines
Education•Quezon City, Philippines•
About: University of the Philippines is a education organization based out in Quezon City, Philippines. It is known for research contribution in the topics: Population & Health care. The organization has 4589 authors who have published 4437 publications receiving 114846 citations. The organization is also known as: UP.
Topics: Population, Health care, Medicine, Adsorption, Public health
Papers published on a yearly basis
Papers
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TL;DR: Infection may act as a trigger for childhood AIS, while routine vaccinations appear protective, Hence, efforts to reduce the spread of common infections might help prevent stroke in children.
Abstract: Objectives: Minor infection can trigger adult arterial ischemic stroke (AIS) and is common in childhood. We tested the hypotheses that infection transiently increases risk of AIS in children, regardless of stroke subtype, while vaccination against infection is protective. Methods: The Vascular Effects of Infection in Pediatric Stroke study is an international case-control study that prospectively enrolled 355 centrally confirmed cases of AIS (29 days–18 years old) and 354 stroke-free controls. To determine prior exposure to infections and vaccines, we conducted parental interviews and chart review. Results: Median (interquartile range) age was 7.6 years for cases and 9.3 for controls ( p = 0.44). Infection in the week prior to stroke, or interview date for controls, was reported in 18% of cases, vs 3% of controls, conferring a 6.3-fold increased risk of AIS ( p p = 0.0002). In an age-adjusted multivariate logistic regression model, independent risk factors for AIS included infection in the prior week (OR 6.3, p p = 0.0004), black race (compared to white; OR 1.9, p = 0.009), and rural residence (compared to urban; OR 3.0, p = 0.0003). Conclusions: Infection may act as a trigger for childhood AIS, while routine vaccinations appear protective. Hence, efforts to reduce the spread of common infections might help prevent stroke in children.
93 citations
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TL;DR: Preoperative administration of single-dose antibiotic for tension-free inguinal mesh herniorrhaphy did not markedly decrease risk of wound infection in this patient population, and results do not support use of antibiotic prophylaxis for tense-free mesh hermiorrhphy.
Abstract: BACKGROUND: In recent years, use of prosthetic material for inguinal hernia repair has increased dramatically. Tension-free repairs have gained popularity not only for recurrent or complicated hernias, but for primary hernia repairs as well. Although routine use of prophylactic antibiotics is not recommended in the Philippines for open nonimplant herniorrhaphy, there is little direct clinical evidence on which to base recommendations when implantable mesh is used. STUDY DESIGN: We conducted a prospective, randomized, double-blind, placebo-controlled trial comparing wound infection rates in 360 patients (180 received prophylactic antibiotics, 180 received a placebo) undergoing primary inguinal hernia repair electively using polypropylene mesh. Age, gender, American Society of Anesthesiologists class, type of hernia, type of anesthesia, and duration of operation were recorded. Infections were evaluated 1 week, 2 weeks, and 1 month after operation by an independent surgeon. All complications were recorded. Results were assessed using chi-square, Fisher's exact test, and Student's t-tests as appropriate. RESULTS: Groups were well matched for all preoperative variables studied, including comorbid conditions. Six patients from the antibiotic group and four from the placebo group failed to followup after the second week. Superficial surgical site infection developed in 3 patients (1.7%) from the antibiotic group and 6 (3.3%) from the placebo group (p = 0.50). One from each group developed deep surgical site infection. Both patients were readmitted and underwent repeated debridement, which eventually resulted in graft loss. CONCLUSIONS: Preoperative administration of single-dose antibiotic for tension-free inguinal mesh herniorrhaphy did not markedly decrease risk of wound infection in this patient population. Our results do not support use of antibiotic prophylaxis for tension-free mesh herniorrhaphy.
93 citations
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Population Health Research Institute1, University of the Philippines2, University of Würzburg3, University of Washington Medical Center4, Brigham and Women's Hospital5, Katholieke Universiteit Leuven6, National University of Ireland, Galway7, Bayer8, Semmelweis University9, Catholic University of Korea10, Centra11, Charles University in Prague12, University of Washington13, University College London14, Karolinska Institutet15, University of the Philippines Manila16, University of La Frontera17, University of Cape Town18, Aalborg University19, Jagiellonian University20, University of Glasgow21, Monash University22, Universiti Teknologi MARA23, University of Paris24, University of Edinburgh25
TL;DR: Routine use of proton pump inhibitors in patients receiving low-dose anticoagulation and/or aspirin for stable cardiovascular disease does not reduce upper gastrointestinal events but may reduce bleeding from gastroduodenal lesions.
92 citations
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TL;DR: Primary LI in childhood is mostly transient and improves with resolution of the underlying pathology, and there is ongoing confusion between LI and cow’s milk allergy (CMA), which still leads to misdiagnosis and inappropriate dietary management.
92 citations
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TL;DR: In this paper, the authors investigated the life cycle environmental sustainability of both home and community installations, designed as part of this work, which utilise diesel, solar, and wind resources coupled with battery storage.
92 citations
Authors
Showing all 4621 results
Name | H-index | Papers | Citations |
---|---|---|---|
Barry M. Popkin | 157 | 751 | 90453 |
Aldo P. Maggioni | 134 | 940 | 90242 |
Michael H. Weisman | 92 | 460 | 39567 |
Johan Ärnlöv | 91 | 386 | 90490 |
Sheila K. West | 89 | 499 | 33719 |
Young Ho Kim | 82 | 2528 | 47681 |
Min Gu | 78 | 729 | 22238 |
Mary L. Marazita | 77 | 436 | 21909 |
Kathleen J. Green | 74 | 193 | 14752 |
Agnes R. Quisumbing | 72 | 311 | 18433 |
Thomas M. Brooks | 71 | 215 | 33724 |
Rigoberto C. Advincula | 65 | 409 | 13632 |
Carl Abelardo T. Antonio | 60 | 106 | 66867 |
Rai S. Kookana | 60 | 281 | 14520 |
J. Kevin Baird | 56 | 185 | 12363 |