Showing papers in "International Journal for Parasitology in 2019"
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TL;DR: The current method for the recovery of Giardia cysts from food matrices using immunomagnetic separation requires further standardisation and cost reduction and should incorporate downstream molecular procedures for genotyping, and traceback and viability analyses.
120 citations
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TL;DR: Deep amplicon sequencing is described as a powerful new approach to detect and quantify the frequency of single nucleotide polymorphisms associated with benzimidazole resistance in parasitic nematode populations of both animals and humans and can reliably detect resistance alleles down to a frequency of 0.1%, making it particularly valuable for screening mutations in the early stages of resistance.
70 citations
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TL;DR: The isolate described represents the first multidrug-resistant strain of A. caninum reported, and the data reveal a resistance marker that can emerge naturally in response to heavy anthelminthic treatment.
49 citations
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TL;DR: Poorly understood interactions between Babesia parasites and their hosts can be effectively addressed with new technologies, but effective control of babesiosis will require additional extensive integrative research strategies.
49 citations
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TL;DR: It is shown that humans have inadvertently precipitated the expansion of C. felis throughout the world, promoting diverse population structure and bioclimatic plasticity and revealing the drivers behind the establishment and success of the cat flea as a global parasite.
48 citations
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TL;DR: Evidence that the enzootic tick vector is the winter tick, Dermacentor albipictus, and the reservoir host is likely the mule deer, Odocoileus hemionus is provided, consistent with confirmed cases of B. duncani in the far-western United States.
45 citations
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TL;DR: Analysis of salmon louse infestation on Atlantic salmon in triplicate commercial snorkel louse barrier and standard cages over a 12 month production cycle serves as a template to validate performance and detect weaknesses in anti-parasite techniques in fish mariculture.
41 citations
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TL;DR: An evident host-associated evolutionary pattern in all parts of the Myxobolus clade with a distinct and species-rich subclade containing almost exclusively species infecting species of the Order Cypriniformes is revealed.
40 citations
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TL;DR: In this paper, the authors carried out a cohort study in Kanchanaburi and Ratchaburi provinces on the Thailand-Myanmar border to determine epidemiological parameters as well as risk factors for malaria infection in western Thailand.
38 citations
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TL;DR: Data support the hypothesis that the sporozoite is a tightly programmed stage to infect the human host and identify mechanisms for hypnozoite formation that may be further explored in liver stage models.
34 citations
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TL;DR: The need to reconsider the use of MAT serology in natural populations of house mice is highlighted and the first known data about T. gondii genetic diversity in invasive and native species of small mammals from Africa is provided.
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TL;DR: It is concluded that interplay between resident cyathostomin populations and the bacterial microbiota of the equine large intestine is important in maintaining homeostasis and that disturbance of this ecology can lead to gut dysbiosis and play a role in the aetiology of inflammatory conditions in the horse, including acute larval cyATHostominosis.
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TL;DR: The data show that O. cornuta is a host of C. mellificae and suggest that males are more susceptible, and the higher mortality of infected honeybees proposes a mechanism for correlated infections and colony mortalities.
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TL;DR: This is the first reported comprehensive, large-scale proteomic investigation of the barber's pole worm (Haemonchus contortus) and revealed substantial alterations in protein profiles during the life cycle, particularly in the transition from the free-living to the parasitic phase.
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TL;DR: This is the first report of a major outbreak of severe diarrhea caused by C. parvum IIdA19G1 in dairy calves in China and more attention should be directed toward preventing the dissemination of this virulent subtype in China.
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TL;DR: In this article, the authors used an unbiased sample processing approach with RNA serving as starting material for the identification of parasites in swine faeces, using the taxonomic identification tool RIEMS, which provided basic hints on potential pathogens contained in the datasets.
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TL;DR: Although there were similar responses of prevalence to some factors, infection patterns were generally bird species-specific, and prevalence is a labile epidemiological parameter, varying spatiotemporally in an idiosyncratic way.
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TL;DR: In this paper, the authors used the B. microti genome sequence to identify 54 genes that are predicted to encode surface-displayed and secreted proteins expressed during the blood stages, and showed that 41 (76%) are expressed using their method at detectable levels.
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TL;DR: The immunological and biological literature of glycosylphosphatidylinositol (GPI)-anchored merozoite proteins of human Babesia parasites with emphasis on their role in immunity, and some new bioinformatical information on B. microti GPI-Anchored Proteins is reviewed.
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TL;DR: Overall, it is concluded that fitness-related costs increased in the resistant strain of cockroaches compared with the susceptible strain, and the variation in insect gut microbiota, especially those related to growth and development, was an important influencing factor.
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TL;DR: The results provide valuable information on parasite survival strategies and new insights into the role of these EVs in the establishment and persistence of hydatid cysts.
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TL;DR: Ascaris infection was associated with a profound change in the gut microbiome, especially in the proximity of the initial site of larval infection, and should facilitate the understanding of the pathophysiological consequence of gastrointestinal nematode infections.
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TL;DR: Investigating the effect of fasciolosis on the parameters of carcass quality and the hypothesis that the effects on weight differ among age ranges of cattle found infection with F. hepatica was positively associated with poor conformations and lower fat scores of carcasses.
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TL;DR: It is demonstrated that dispersal models coupled with network analysis can identify no-farming zones that fragment dispersal networks, which should lower infection pressure at farms, slow the evolution of resistance to parasite control measures, and alleviate infection pressure on wild salmon populations.
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TL;DR: In this article, the authors showed that Toxoplasma strains that are severely virulent in laboratory inbred mice are avirulent in some other mouse sub-species, such as M. m. domesticus and Mus musculus castaneus, and that this is due to a locus on chromosome 11 that includes the genes that encode the interferon gamma (IFNG)-inducible immunity-related GTPases.
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TL;DR: In the context of regular deworming, few water, sanitation and hygiene-related factors were associated with soil-transmitted helminth infections, particularly in low transmission settings after cessation of de Worming.
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TL;DR: Results demonstrate a lack of concordance between the presence of viable parasites in liver and the detection of T. gondii DNA in diaphragm, demonstrating that serological testing by MAT or p30 immunoblot does not provide information about the presenceof T. Gondii parasites or DNA in cattle and therefore is not a reliable indicator of the risk for consumers.
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TL;DR: The highest fatal and non-fatal burden due to Chagas disease was observed among males, the elderly, and in those Brazilian states encompassing important endemic areas for vector transmission in the past.
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TL;DR: It is observed that high B. microti parasitaemia leads to low haemoglobin levels in infected mice, reflecting the anaemia observed in human babesiosis, and that B. burgdorferi coinfection attenuates parasite growth while B.microti presence exacerbates Lyme disease-like symptoms in mice.
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TL;DR: The chemopreventive effect of RSV targeting biliary neoplasia formation might be useful for improving the outcomes in infected populations and represents a compelling rationale for RSV testing in combination chemotherapy of opisthorchiasis.