Journal•ISSN: 0165-5728
Journal of Neuroimmunology
Elsevier BV
About: Journal of Neuroimmunology is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Multiple sclerosis & Immune system. It has an ISSN identifier of 0165-5728. Over the lifetime, 8844 publications have been published receiving 327030 citations. The journal is also known as: JNI.
Topics: Multiple sclerosis, Immune system, Experimental autoimmune encephalomyelitis, T cell, Antigen
Papers published on a yearly basis
Papers
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TL;DR: The role of specific cell types including leukocytes, endothelium, glia, microglia, the extracellular matrix and neurons, and mediators produced by inflammatory cells such as cytokines, chemokines, reactive oxygen species and arachidonic acid metabolites are reviewed.
1,096 citations
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TL;DR: Since BV-2 cells retain most of the morphological, phenotypical and functional properties described for freshly isolated microglial cells, it can be concluded that J2 virus infection has resulted in the immortalization of active microglia cells.
952 citations
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TL;DR: Electron microscopy data suggest that amyloid deposition may precede the activation of microglia and that HLA-DR-positive reactivemicroglia embedded in their core may be in intimate contact with amyloids fibrils.
915 citations
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TL;DR: While inflammation has been thought to arise secondary to degeneration, recent experiments demonstrated that inflammatory mediators may stimulate APP processing by upregulation of beta secretase 1 and therefore are able to establish a vicious cycle.
895 citations
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TL;DR: The glial fibrillary acidic protein (GFA protein or GFAP) is the major protein constituent of glial intermediate filaments in differentiated fibrous and protoplasmic astrocytes of the central nervous system.
690 citations