A differential neural response in the human amygdala to fearful and happy facial expressions
J. S. Morris,Chris D. Frith,David I. Perrett,Duncan Rowland,Andrew W. Young,Andrew J. Calder,Raymond J. Dolan +6 more
TLDR
Direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness is reported, providing direct evidence that the humangdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.Abstract:
The amygdala is thought to play a crucial role in emotional and social behaviour. Animal studies implicate the amygdala in both fear conditioning and face perception. In humans, lesions of the amygdala can lead to selective deficits in the recognition of fearful facial expressions and impaired fear conditioning, and direct electrical stimulation evokes fearful emotional responses. Here we report direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness. Positron-emission tomography (PET) measures of neural activity were acquired while subjects viewed photographs of fearful or happy faces, varying systematically in emotional intensity. The neuronal response in the left amygdala was significantly greater to fearful as opposed to happy expressions. Furthermore, this response showed a significant interaction with the intensity of emotion (increasing with increasing fearfulness, decreasing with increasing happiness). The findings provide direct evidence that the human amygdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.read more
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Intact recognition of facial emotion in Parkinson's disease.
TL;DR: The findings do not support the notion that the sectors of basal ganglia that are dysfunctional in Parkinson's disease are essential for recognizing emotion in facial expressions.
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Passive and Active Recognition of One's Own Face
Motoaki Sugiura,Ryuta Kawashima,Ryuta Kawashima,Katsuki Nakamura,Ken Okada,Takashi Kato,Akinori Nakamura,Kentaro Hatano,Kengo Itoh,Shozo Kojima,Hiroshi Fukuda,Hiroshi Fukuda +11 more
TL;DR: In this article, the authors performed a PET activation study with normal volunteers in facial identity recognition tasks using the subject's own face as visual stimulus and found that the prefrontal cortices, the right anterior cingulate, right presupplementary motor area, and the left insula were specifically activated during task A compared with tasks C and P, indicating that these regions may be involved in the sustained attention to the representation of one's face.
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Differential electrocortical responses to increasing intensities of fearful and happy emotional expressions.
TL;DR: Results suggest that differential electrocortical responses to fearful facial expressions over posterior electrodes are generated by a neural system that responds to the intensity of negative but not positive emotional expressions.
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Early processing of emotional faces in children with autism: An event-related potential study.
TL;DR: The results suggest that the emotional and facial processing difficulties in autism could start from atypicalities in visual perceptual processes involving rapid feedback to primary visual areas and subsequent holistic processing.
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Relation Between Amygdala Structure and Function in Adolescents With Bipolar Disorder
Jessica H. Kalmar,Fei Wang,Lara G. Chepenik,Fay Y. Womer,Monique M. Jones,Brian Pittman,Maulik P. Shah,Andrés Martin,R. Todd Constable,Hilary P. Blumberg +9 more
TL;DR: This study represents the first report, to the knowledge, of the two findings in the same adolescent BD sample and supports an amygdala structure-function relation characterized by an inverse association between volume and response to emotional stimuli.
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Ralph Adolphs,Daniel Tranel,Hanna Damasio,Hanna Damasio,Antonio R. Damasio,Antonio R. Damasio +5 more
TL;DR: Findings suggest the human amygdala may be indispensable to recognize fear in facial expressions, but is not required to recognize personal identity from faces, and constrains the broad notion that the amygdala is involved in emotion.