A differential neural response in the human amygdala to fearful and happy facial expressions
J. S. Morris,Chris D. Frith,David I. Perrett,Duncan Rowland,Andrew W. Young,Andrew J. Calder,Raymond J. Dolan +6 more
TLDR
Direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness is reported, providing direct evidence that the humangdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.Abstract:
The amygdala is thought to play a crucial role in emotional and social behaviour. Animal studies implicate the amygdala in both fear conditioning and face perception. In humans, lesions of the amygdala can lead to selective deficits in the recognition of fearful facial expressions and impaired fear conditioning, and direct electrical stimulation evokes fearful emotional responses. Here we report direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness. Positron-emission tomography (PET) measures of neural activity were acquired while subjects viewed photographs of fearful or happy faces, varying systematically in emotional intensity. The neuronal response in the left amygdala was significantly greater to fearful as opposed to happy expressions. Furthermore, this response showed a significant interaction with the intensity of emotion (increasing with increasing fearfulness, decreasing with increasing happiness). The findings provide direct evidence that the human amygdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.read more
Citations
More filters
Journal ArticleDOI
The development of emotional face processing during childhood.
TL;DR: Despite the precocious utilization of facial emotions, the neural processing involved in the perception of emotional faces develops in a staggered fashion throughout childhood, with the adult pattern appearing only late in adolescence.
Journal ArticleDOI
Processing faces and facial expressions.
Mette T. Posamentier,Hervé Abdi +1 more
TL;DR: This paper reviews processing of facial identity and expressions and finds activation patterns in response to facial expressions support the notion of involved neural substrates for processing different facial expressions.
Journal ArticleDOI
Differential neural responses to overt and covert presentations of facial expressions of fear and disgust
Mary L. Phillips,Leanne M. Williams,Maike Heining,Catherine M. Herba,Tamara Russell,Christopher Andrew,Edward T. Bullmore,Michael Brammer,Steven Williams,Michael J. Morgan,Andrew W. Young,Jeffrey A. Gray +11 more
TL;DR: Findings demonstrate significant differences between the neural responses to fear and to disgust, and between the covert presentations of these two emotions, and suggest distinct neural correlates of conscious and unconscious emotion perception.
Journal ArticleDOI
The amygdala as a hub in brain networks that support social life
TL;DR: This work synthesizes extant anatomical and functional data from rodents, monkeys, and humans to describe the topography of three partially distinct large-scale brain networks anchored in the amygdala that each support unique functions for effectively managing social interactions and maintaining social relationships.
Journal ArticleDOI
Affective cognition and its disruption in mood disorders.
TL;DR: In this review, affective cognition, responses to emotional stimuli occurring in the context of cognitive evaluation, is considered, in particular, emotion categorization, biasing of memory and attention, as well as social/moral emotion.
References
More filters
Journal ArticleDOI
Statistical parametric maps in functional imaging: A general linear approach
Karl J. Friston,Andrew P. Holmes,Keith J. Worsley,J-B. Poline,Chris D. Frith,Richard S. J. Frackowiak +5 more
TL;DR: In this paper, the authors present a general approach that accommodates most forms of experimental layout and ensuing analysis (designed experiments with fixed effects for factors, covariates and interaction of factors).
Book
The Expression of the Emotions in Man and Animals
TL;DR: The Expression of the Emotions in Man and Animals Introduction to the First Edition and Discussion Index, by Phillip Prodger and Paul Ekman.
Journal ArticleDOI
Spatial registration and normalization of images
Karl J. Friston,John Ashburner,Chris D. Frith,Jean-Baptiste Poline,Jon D. Heather,Richard S. J. Frackowiak +5 more
TL;DR: A general technique that facilitates nonlinear spatial (stereotactic) normalization and image realignment is presented that minimizes the sum of squares between two images following non linear spatial deformations and transformations of the voxel (intensity) values.
Journal ArticleDOI
Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala.
Ralph Adolphs,Daniel Tranel,Hanna Damasio,Hanna Damasio,Antonio R. Damasio,Antonio R. Damasio +5 more
TL;DR: Findings suggest the human amygdala may be indispensable to recognize fear in facial expressions, but is not required to recognize personal identity from faces, and constrains the broad notion that the amygdala is involved in emotion.