A differential neural response in the human amygdala to fearful and happy facial expressions
J. S. Morris,Chris D. Frith,David I. Perrett,Duncan Rowland,Andrew W. Young,Andrew J. Calder,Raymond J. Dolan +6 more
TLDR
Direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness is reported, providing direct evidence that the humangdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.Abstract:
The amygdala is thought to play a crucial role in emotional and social behaviour. Animal studies implicate the amygdala in both fear conditioning and face perception. In humans, lesions of the amygdala can lead to selective deficits in the recognition of fearful facial expressions and impaired fear conditioning, and direct electrical stimulation evokes fearful emotional responses. Here we report direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness. Positron-emission tomography (PET) measures of neural activity were acquired while subjects viewed photographs of fearful or happy faces, varying systematically in emotional intensity. The neuronal response in the left amygdala was significantly greater to fearful as opposed to happy expressions. Furthermore, this response showed a significant interaction with the intensity of emotion (increasing with increasing fearfulness, decreasing with increasing happiness). The findings provide direct evidence that the human amygdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.read more
Citations
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Fearful faces in schizophrenia: the relationship between patient characteristics and facial affect recognition.
Mascha van 't Wout,Annemiek van Dijke,André Aleman,Roy P. C. Kessels,Wietske Pijpers,René S. Kahn +5 more
TL;DR: Investigation of whether particular patient characteristics are associated with the recognition of specific facial expressions in patients with schizophrenia found that negative symptoms and male sex were associated with worse recognition of fearful faces.
Journal ArticleDOI
The neural mechanism of imagining facial affective expression.
Sung Eun Kim,Ji-Woong Kim,Jae Jin Kim,Bumseok Jeong,Eun Ae Choi,Young Gil Jeong,Ji Hyung Kim,Jeonghun Ku,Seon Wan Ki +8 more
TL;DR: Given that the processing of information concerning the facial patterning of different emotions and the enactment of behavioral responses, such as autonomic arousal, are central components of the imagery of emotional facial expressions, the central role of the amygdala is postulate.
Journal ArticleDOI
Differential effects of object-based attention on evoked potentials to fearful and disgusted faces.
TL;DR: Results indicated that the perception of fear from faces is gated by selective attention at early latencies, whereas a sustained positivity for fearful faces compared to neutral faces emerged around 160ms at central-parietal sites, independent of selective attention.
Journal ArticleDOI
A comparison of the effects of a β-adrenergic blocker and a benzodiazepine upon the recognition of human facial expressions
TL;DR: Findings are interpreted as providing further support for the suggestion that there are dissociable systems responsible for processing emotional expressions, and may have implications for understanding why 'paradoxical' aggression is sometimes elicited by benzodiazepines.
Journal ArticleDOI
Neural Responses to Rapid Facial Expressions of Fear and Surprise
TL;DR: It was found that fearful faces evoked greater activity in the left precuneus, middle temporal gyrus (MTG), middle frontal gyrus, and right lingual g Cyrus, whereas surprised faces were associated with greaterActivity in the right postcentral gyrus and left posterior insula.
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Karl J. Friston,John Ashburner,Chris D. Frith,Jean-Baptiste Poline,Jon D. Heather,Richard S. J. Frackowiak +5 more
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Ralph Adolphs,Daniel Tranel,Hanna Damasio,Hanna Damasio,Antonio R. Damasio,Antonio R. Damasio +5 more
TL;DR: Findings suggest the human amygdala may be indispensable to recognize fear in facial expressions, but is not required to recognize personal identity from faces, and constrains the broad notion that the amygdala is involved in emotion.