A differential neural response in the human amygdala to fearful and happy facial expressions
J. S. Morris,Chris D. Frith,David I. Perrett,Duncan Rowland,Andrew W. Young,Andrew J. Calder,Raymond J. Dolan +6 more
TLDR
Direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness is reported, providing direct evidence that the humangdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.Abstract:
The amygdala is thought to play a crucial role in emotional and social behaviour. Animal studies implicate the amygdala in both fear conditioning and face perception. In humans, lesions of the amygdala can lead to selective deficits in the recognition of fearful facial expressions and impaired fear conditioning, and direct electrical stimulation evokes fearful emotional responses. Here we report direct in vivo evidence of a differential neural response in the human amygdala to facial expressions of fear and happiness. Positron-emission tomography (PET) measures of neural activity were acquired while subjects viewed photographs of fearful or happy faces, varying systematically in emotional intensity. The neuronal response in the left amygdala was significantly greater to fearful as opposed to happy expressions. Furthermore, this response showed a significant interaction with the intensity of emotion (increasing with increasing fearfulness, decreasing with increasing happiness). The findings provide direct evidence that the human amygdala is engaged in processing the emotional salience of faces, with a specificity of response to fearful facial expressions.read more
Citations
More filters
Journal ArticleDOI
Face perception is mediated by a distributed cortical network.
TL;DR: Results indicate that a mere percept of a face is sufficient to localize activation within the distributed cortical network that mediates the visual analysis of facial identity and expression.
Journal ArticleDOI
Common and distinct neural responses during direct and incidental processing of multiple facial emotions
TL;DR: In this paper, the authors performed an event-related fMRI experiment in which subjects viewed morphed emotional faces displaying low or high intensities of disgust, fear, happiness, or sadness under two task conditions.
Journal ArticleDOI
Thinking like a trader selectively reduces individuals' loss aversion
Peter Sokol-Hessner,Ming Hsu,Nina G. Curley,Mauricio R. Delgado,Colin F. Camerer,Elizabeth A. Phelps +5 more
TL;DR: The intentional cognitive regulation strategy, which emphasized “perspective-taking,” uniquely reduced both behavioral loss aversion and aroused to losses relative to gains, largely by influencing arousal to losses.
Journal ArticleDOI
Regulation of emotional responses elicited by threat-related stimuli
Falk Eippert,Ralf Veit,Nikolaus Weiskopf,Nikolaus Weiskopf,Michael Erb,Niels Birbaumer,Niels Birbaumer,Sillce Anders +7 more
TL;DR: It is demonstrated that amygdala responses to threat‐related stimuli can be controlled through the use of cognitive strategies depending on recruitment of prefrontal areas, thereby changing the subject's affective state.
Journal ArticleDOI
Processing emotional pictures and words: Effects of valence and arousal.
TL;DR: Valence effects were most apparent when the individuals processed pictures, and the results revealed a lateral/medial distinction within the PFC: the lateral PFC responded differentially to negative items, whereas the medial PFC was more engaged during the processing of positive pictures.
References
More filters
Journal ArticleDOI
Statistical parametric maps in functional imaging: A general linear approach
Karl J. Friston,Andrew P. Holmes,Keith J. Worsley,J-B. Poline,Chris D. Frith,Richard S. J. Frackowiak +5 more
TL;DR: In this paper, the authors present a general approach that accommodates most forms of experimental layout and ensuing analysis (designed experiments with fixed effects for factors, covariates and interaction of factors).
Book
The Expression of the Emotions in Man and Animals
TL;DR: The Expression of the Emotions in Man and Animals Introduction to the First Edition and Discussion Index, by Phillip Prodger and Paul Ekman.
Journal ArticleDOI
Spatial registration and normalization of images
Karl J. Friston,John Ashburner,Chris D. Frith,Jean-Baptiste Poline,Jon D. Heather,Richard S. J. Frackowiak +5 more
TL;DR: A general technique that facilitates nonlinear spatial (stereotactic) normalization and image realignment is presented that minimizes the sum of squares between two images following non linear spatial deformations and transformations of the voxel (intensity) values.
Journal ArticleDOI
Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala.
Ralph Adolphs,Daniel Tranel,Hanna Damasio,Hanna Damasio,Antonio R. Damasio,Antonio R. Damasio +5 more
TL;DR: Findings suggest the human amygdala may be indispensable to recognize fear in facial expressions, but is not required to recognize personal identity from faces, and constrains the broad notion that the amygdala is involved in emotion.