A Fluorinated Ionic Liquid-Based Activatable 19F MRI Platform Detects Biological Targets.
Xianglong Zhu,Xianglong Zhu,Xiaoxue Tang,Hongyu Lin,Saige Shi,Hehe Xiong,Qiuju Zhou,Ao Li,Qiaoyang Wang,Xiaoyuan Chen,Jinhao Gao +10 more
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TLDR
Fluinated ion liquids (ILs) are reported as a new type of fluorine agents and a fluorinated ionic liquid-based activatable 19F MRI platform (FILAMP), which relies on the phase transition of ILs, which demonstrates the potential of FILAMP as a robust activatable 18F probe for diagnosis and monitoring of biological and pathological processes.About:
This article is published in Chem.The article was published on 2020-05-14 and is currently open access. It has received 35 citations till now.read more
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Biological Utility of Fluorinated Compounds: from Materials Design to Molecular Imaging, Therapeutics and Environmental Remediation
TL;DR: A review of fluorine-fluorine-containing materials in imaging, therapeutics, and environmental applications is presented in this article, focusing on the design and utility of C-F containing materials.
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The role of plastic concerning the sustainable development goals: The literature point of view
TL;DR: A critical overview of the role of plastic concerning the SDGs, discussing its pros and cons, is provided in this paper, and a future scenario is tried to be outlined, based on a bibliometric mapping and analysis and the recent literature as mentioned in this paper.
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Activatable 19 F MRI Nanoprobes for Visualization of Biological Targets in Living Subjects.
TL;DR: In this paper, a panoramic prospective for the people who are interested in this emerging and exciting field is summarized to summarize the recent progress over the past decades on activatable 19 F MRI nanoprobes made from three major 19 F-containing compounds, as well as present challenges and potential opportunities.
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Reversible redox-responsive 1H/19F MRI molecular probes
Hongming Chen,Xiaoxue Tang,Xuanqing Gong,Dongxia Chen,Ao Li,Chengjie Sun,Hongyu Lin,Jinhao Gao +7 more
TL;DR: A pair of redox-responsive manganese complexes Mn(iii)/(ii)-N,N'-bis(2-hydroxy-4-trifluoromethylbenzyl)ethylenediamine-N, N'-diacetate (HTFBED, L1), which are water soluble and biologically interconvertible, are reported as reversible red ox-responsive probes in 1H/19F MRI for detecting and imaging biological redox species.
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Fluorinated Gadolinium Chelate-Grafted Nanoconjugates for Contrast-Enhanced T1-Weighted 1H and pH-Activatable 19F Dual-Modal MRI.
TL;DR: A highly biocompatible nanoconjugate composed of pH-responsive 19F nucleus-bearing Gd3+ chelates enables significant contrast enhancement for T1-weighted 1H MRI and permits pH- responsive activation of 19F signals for 19F MRI, providing both clear anatomical details of living bodies and the biorelevant molecular information with low background interference.
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