A systematic review of tests to predict cerebral palsy in young children.
Margot Bosanquet,Margot Bosanquet,Margot Bosanquet,Lisa Copeland,Robert S. Ware,Robert S. Ware,Roslyn N. Boyd,Roslyn N. Boyd +7 more
TLDR
This systematic review evaluates the accuracy of predictive assessments and investigations used to assist in the diagnosis of cerebral palsy in preschool‐age children (<5y).Abstract:
Aim
This systematic review evaluates the accuracy of predictive assessments and investigations used to assist in the diagnosis of cerebral palsy (CP) in preschool-age children (<5y).
Method
Six databases were searched for studies that included a diagnosis of CP validated after 2 years of age. The validity of the studies meeting the criteria was evaluated using the Standards for Reporting Diagnostic Accuracy criteria. Where possible, results were pooled and a meta-analysis was undertaken.
Results
Nineteen out of 351 studies met the full inclusion criteria, including studies of general movements assessment (GMA), cranial ultrasound, brain magnetic resonance imaging (MRI), and neurological examination. All studies assessed high-risk populations including preterm (gestational range 23–41wks) and low-birthweight infants (range 500–4350g). Summary estimates of sensitivity and specificity of GMA were 98% (95% confidence interval [CI] 74–100%) and 91% (95% CI 83–93%) respectively; of cranial ultrasound 74% (95% CI 63–83%) and 92% (95% CI 81–96%) respectively; and of neurological examination 88% (95% CI 55–97%) and 87% (95% CI 57–97%) respectively. MRI performed at term corrected age (in preterm infants) appeared to be a strong predictor of CP, with sensitivity ranging in individual studies from 86 to 100% and specificity ranging from 89 to 97% There was inadequate evidence for the use of other predictive tools.
Summary
This review found that the assessment with the best evidence and strength for predictive accuracy is the GMA. MRI has a good predictive value when performed at term-corrected age. Cranial ultrasound is as specific as MRI and has the advantage of being readily available at the bedside. Studies to date have focused on high-risk infants. The accuracy of these tests in low-risk infants remains unclear and requires further research.read more
Citations
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Neuromotor repertoires in infants exposed to maternal COVID-19 during pregnancy: a cohort study
Viviana Fajardo Martinez,Dajie Zhang,Sophia Paiola,Thalia Mok,Mary Catherine Cambou,Tara Kerin,Rashmi Rao,Patrícia Brasil,F. Ferreira,Trevon Fuller,Debika Bhattacharya,Suan-Sin Foo,Weiqiang Chen,Jae-Gu Jung,Christa Einspieler,Peter B. Marschik,Karin Nielsen-Saines +16 more
TL;DR: In this article , the authors evaluated neuromotor repertoires and developmental milestones in infants exposed to antenatal COVID-19 during pregnancy and prepandemic control infants from the Graz University Database.
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Electroencephalography measures of relative power and coherence as reaching skill emerges in infants born preterm.
TL;DR: In this article, the authors investigated the changing patterns of relative power and coherence in the alpha band during resting state EEG in infants born preterm as they developed the skill of reaching.
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The quality of preventive care for pre-school aged children in Australian general practice
Louise Wiles,Louise Wiles,Carl de Wet,Carl de Wet,Chris Dalton,Elisabeth Murphy,Mark Harris,Peter Hibbert,Peter Hibbert,Charlotte J. Molloy,Charlotte J. Molloy,Gaston Arnolda,Hsuen P Ting,Jeffrey Braithwaite,CareTrack Kids Investigative Team +14 more
TL;DR: The findings that preventive care is not reliably delivered to all Australian children and that there is substantial variation in adherence with the IQs provide a starting point for clinicians, researchers and policy makers when considering how the gap between recommended and actual care may be narrowed.
Dissertation
Detección temprana de alteraciones del desarrollo mediante la aplicación de la Pauta Breve de Derivación
TL;DR: La PBD es una herramienta sencilla y facil de aplicar, that demuestra una correlacion entre the puntuacion obtenida y the valoracion neurocinesiologica de Vojta, expresada como alteracion in la coordinacion central.
Journal ArticleDOI
High Prevalence of Abnormal General Movements in Hospitalized Very Low Birth Weight Infants
Corrie J. Alonzo,Lisa Letzkus,Elizabeth A. Connaughton,Nancy Kelly,Joseph A. Michel,Santina A. Zanelli +5 more
TL;DR: In this paper, the authors describe the implementation of the GM assessment (GMA) in a neonatal intensive care unit (NICU) and investigate the prevalence and evolution of abnormal general movements in very low birth weight (VLBW) infants.
References
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Journal ArticleDOI
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TL;DR: Suggestions were made about the content of a revised definition and classification of CP that would meet the needs of clinicians, investigators, health officials, families and the public and would provide a common language for improved communication.
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