Journal ArticleDOI
Amorphous pharmaceutical solids: preparation, characterization and stabilization.
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TLDR
Current research in the stabilization of amorphous solids focuses on the stabilize of labile substances during processing and storage using additives, the prevention of crystallization of the excipients that must remainAmorphous for their intended functions, and the selection of appropriate storage conditions under which amorphously solids are stable.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2001-05-16. It has received 1367 citations till now. The article focuses on the topics: Amorphous solid & Crystallization.read more
Citations
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Development and optimization of spray-dried functional oil microcapsules: Oxidation stability and release kinetics.
TL;DR: In vitro oil release of microencapsulated functional oil containing HACS has a better sustained release effect and this formulation of microcapsules was satisfactorily applied in powdered food for diabetic patients.
Journal ArticleDOI
Concomitant cocrystallization on engineered surfaces
TL;DR: In this paper, the authors obtained new polymorphs of the cocrystals of caffeine and oxalic acid (2':'1 molar ratio), which showed new peaks at 1076, 1588 and 1602 cm−1.
Journal ArticleDOI
A Difração de Raios X: uma Técnica de Investigação da Estrutura Cristalina de Materiais
TL;DR: X-ray diffraction (XRD) is a powerful non-destructive technique for crystalline material characterization as mentioned in this paper, which provides information about the structures, phases, crystal orientation and other structural parameters, such as average size of the grain, crystallinity, tension and crystal defects.
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Interpreting the Activated Rate Theory for Solid-Phase Crystallization: Comparing Lactose and Sucrose
TL;DR: The activation enthalpy for solid-phase crystal growth has been found to be 39±2kJ/mol for liquid-phase crystallization and 68−4kJ /mol for solid phase crystallization as mentioned in this paper.
References
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Journal ArticleDOI
On the Temperature Dependence of Cooperative Relaxation Properties in Glass‐Forming Liquids
Gerold Adam,Julian H. Gibbs +1 more
TL;DR: In this paper, a molecularkinetic theory was proposed to explain the temperature dependence of relaxation behavior in glass-forming liquids in terms of the temperature variation of the size of the cooperatively rearranging region.
Book
The theory of transformations in metals and alloys : an advanced textbook in physical metallurgy
Journal ArticleDOI
Formation of glasses from liquids and biopolymers.
TL;DR: The onset of a sharp change in ddT( is the Debye-Waller factor and T is temperature) in proteins, which is controversially indentified with the glass transition in liquids, is shown to be general for glass formers and observable in computer simulations of strong and fragile ionic liquids, where it proves to be close to the experimental glass transition temperature.
Book
The theory of transformations in metals and alloys
J.W. Christian,H. M. Otte +1 more
TL;DR: In this paper, the authors present a general introduction to the theory of transformation kinetics of real metals, including the formation and evolution of martensitic transformations, as well as a theory of dislocations.
Journal ArticleDOI
Nonexponential relaxations in strong and fragile glass formers
TL;DR: In this article, a broad correlation of non-debye behavior with non-Arrhenius relaxations was found for different types of glass formers, distinguished by their respective molecular complexity.
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