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Journal ArticleDOI

An Aptamer Cross-Linked Hydrogel as a Colorimetric Platform for Visual Detection

TLDR
This work aims to demonstrate the efforts towards in-situ applicability of EMMARM, which aims to provide real-time information about the physical properties of EMTs through direct observation and computer simulation.
Abstract
US NIH ; China National Scientific Foundation of China [20805038, 20620130427]; National Basic Research Program of China [2007CB935603, 2010CB732402, 2009ZX10004-312]; ACS Division of Analytical Chemistry

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Isothermal Amplification of Nucleic Acids

TL;DR: This review provides a comprehensive overview of the isothermal amplification of nucleic acids encompassing work published in the past two decades including applications in bioanalysis, diagnostics, nanotechnology, materials science, and device integration.
Journal ArticleDOI

Aptamer in bioanalytical applications.

TL;DR: As the first review of aptamers on Analytical Chemistry, this work attempts to cover major progresses in bioanalytical applications of aptamer research in the past 2 years.
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Supramolecular self-assemblies as functional nanomaterials

TL;DR: This compilation illustrates how, based on the rules of supramolecular chemistry, the bottom-up approach to design functional objects at the nanoscale is currently producing highly sophisticated materials oriented towards a growing number of applications with high societal impact.
References
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Journal ArticleDOI

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

TL;DR: High-affinity nucleic acid ligands for a protein were isolated by a procedure that depends on alternate cycles of ligand selection from pools of variant sequences and amplification of the bound species.
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A DNA-based Method for Rationally Assembling Nanoparticles Into Macroscopic Materials

TL;DR: A method for assembling colloidal gold nanoparticles rationally and reversibly into macroscopic aggregates by using the specificity of DNA interactions to direct the interactions between particles of different size and composition is described.
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Nanostructures in Biodiagnostics

TL;DR: Nathaniel L. Rosi focuses on the rational assembly of DNA-modified nanostructures into larger-scale materials and their roles in biodiagnostic screening for nucleic acids.
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Nanoparticles with Raman Spectroscopic Fingerprints for DNA and RNA Detection

TL;DR: Six dissimilar DNA targets with six Raman-labeled nanoparticle probes were distinguished, as well as two RNA targets with single nucleotide polymorphisms, and the current unoptimized detection limit of this method is 20 femtomolar.
Journal ArticleDOI

Patterned Paper as a Platform for Inexpensive, Low‐Volume, Portable Bioassays

TL;DR: This communication describes a simple method for patterning paper to create well-defined, millimeter-sized channels, comprising hydrophilic paper bounded by hydrophobic polymer, that will become the basis for low-cost, portable, and technically simple multiplexed bioassays.
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