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Anti-cancer drugs
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This article is published in Current Pharmaceutical Design.The article was published on 2005-03-31. It has received 882 citations till now. The article focuses on the topics: Introductory Journal Article.read more
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Essential Oils and Antioxidants Derived From Citrus By-Products in Food Protection and Medicine: An Introduction and Review of Recent Literature
TL;DR: Citrus oils have been used as a part of the perfume industry and in the practice of alternative medicine for a long time, but now there is a great deal of mainstream food processing and drug industry interest in them owing to the rediscovery or confirmation of some of their beneficial properties, as well their development for entirely new applications as mentioned in this paper.
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Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression
TL;DR: Combined intravesical chemotherapy may provide a viable bladder-sparing treatment alternative for patients at high risk for developing invasive bladder cancer, which can be evaluated in appropriate clinical trials.
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The Estrogen-responsive B Box Protein Is a Novel Regulator of the Retinoid Signal
Belamy B. Cheung,Jessica L. Bell,Anna Raif,Andrew Bohlken,Joanne Yan,Ben Roediger,Anne Poljak,Stewart A. Smith,Michelle Lee,Wayne Thomas,Maria Kavallaris,Murray D. Norris,Michelle Haber,Hsiao-Lai Liu,Deborah A. Zajchowski,Glenn M. Marshall +15 more
TL;DR: It is shown that the estrogen-responsive B box protein (EBBP), a member of the RING-B box-coiled-coil protein family, is a βRARE-binding protein, which suggests that EBBP may have a pivotal role in the retinoid anti-cancer signal.
Journal ArticleDOI
Comparative studies of the antioxidant effects of a naturally occurring resveratrol analogue -- trans-3,3',5,5'-tetrahydroxy-4'-methoxystilbene and resveratrol -- against oxidation and nitration of biomolecules in blood platelets.
Beata Olas,Barbara Wachowicz,Pawel Nowak,Anna Stochmal,Wieslaw Oleszek,Rafał Głowacki,Edward Bald +6 more
TL;DR: In vitro trans-3,3′, 5,5,5′-tetrahydroxy-4′-methoxystilbene and resveratrol have very similar protective effects against peroxynitrite-induced oxidative/nitrative damage to the human platelet proteins and lipids.
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miRNAs as prognostic and therapeutic tools in epithelial ovarian cancer
TL;DR: This review discusses the emerging role ofmiRNAs in regulating EOC phenotype with a focus on prognostic and therapeutic importance of miRNAs and the possibility of miRNA modulation as a tool to improve efficacy of chemotherapy in EOC.
References
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The status of platinum anticancer drugs in the clinic and in clinical trials.
TL;DR: The status of platinum anticancer drugs currently approved for use, those undergoing clinical trials and those discontinued during clinical trials are updated, and the results in the context of where the field will develop over the next decade are discussed.
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Natural products to drugs: natural product derived compounds in clinical trials
Mark S. Butler,Mark S. Butler +1 more
TL;DR: Natural product and natural product-derived compounds that are being evaluated in clinical trials or are in registration (as at 31st December 2007) have been reviewed, as well as natural products for which clinical trials have been halted or discontinued since 2005.
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Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs)
John Ramage,A Ahmed,J Ardill,N.D.S. Bax,David J. Breen,Martyn Caplin,Pippa Corrie,J Davar,Albert Davies,Val Lewington,Tim Meyer,John Newell-Price,Graeme J. Poston,N. Reed,Andrea Rockall,William P. Steward,Rajesh V. Thakker,C. Toubanakis,Juan W. Valle,Caroline S. Verbeke,Ashley B. Grossman +20 more
TL;DR: These guidelines update previous guidance published in 2005 and have been revised by a group who are members of the UK and Ireland Neuroendocrine Tumour Society with endorsement from the clinical committees of the British Society of Gastroenterology and others.
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Cellular distribution and functions of P2 receptor subtypes in different systems.
TL;DR: This review is aimed at providing readers with a comprehensive reference article about the distribution and function of P2 receptors in all the organs, tissues, and cells in the body.
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Natural products: an evolving role in future drug discovery.
Bhuwan B. Mishra,Vinod K. Tiwari +1 more
TL;DR: The present review describes natural products, semi-synthetic NPs and NP-derived compounds that have undergone clinical evaluation or registration from 2005 to 2010 by disease area i.e. infectious, immunological, cardiovascular, neurological, inflammatory and related diseases and oncology.