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Journal ArticleDOI

Anti-cancer drugs

Elke S. Bergmann-Leitner
- 31 Mar 2005 - 
- Vol. 14, Iss: 11, pp 1048-1048
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This article is published in Current Pharmaceutical Design.The article was published on 2005-03-31. It has received 882 citations till now. The article focuses on the topics: Introductory Journal Article.

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The status of platinum anticancer drugs in the clinic and in clinical trials.

Nial J. Wheate, +3 more
- 25 Aug 2010 - 
TL;DR: The status of platinum anticancer drugs currently approved for use, those undergoing clinical trials and those discontinued during clinical trials are updated, and the results in the context of where the field will develop over the next decade are discussed.
Journal ArticleDOI

Natural products to drugs: natural product derived compounds in clinical trials

Mark S. Butler, +1 more
- 31 Mar 2005 - 
TL;DR: Natural product and natural product-derived compounds that are being evaluated in clinical trials or are in registration (as at 31st December 2007) have been reviewed, as well as natural products for which clinical trials have been halted or discontinued since 2005.
Journal ArticleDOI

Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs)

John Ramage, +20 more
- 01 Jun 2005 - 
TL;DR: These guidelines update previous guidance published in 2005 and have been revised by a group who are members of the UK and Ireland Neuroendocrine Tumour Society with endorsement from the clinical committees of the British Society of Gastroenterology and others.
Journal ArticleDOI

Cellular distribution and functions of P2 receptor subtypes in different systems.

Geoffrey Burnstock, +1 more
- 01 Jan 2004 - 
TL;DR: This review is aimed at providing readers with a comprehensive reference article about the distribution and function of P2 receptors in all the organs, tissues, and cells in the body.
Journal ArticleDOI

Natural products: an evolving role in future drug discovery.

Bhuwan B. Mishra, +1 more
- 01 Oct 2011 - 
TL;DR: The present review describes natural products, semi-synthetic NPs and NP-derived compounds that have undergone clinical evaluation or registration from 2005 to 2010 by disease area i.e. infectious, immunological, cardiovascular, neurological, inflammatory and related diseases and oncology.
References
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Synthesis, Structure, and Peroxidase Activity of an Octahedral Ru(III) Complex with a Tripodal Tetraamine Ligand

Jang Hoon Cho, +3 more
- 20 Nov 2011 - 
TL;DR: A new octahedral Ru(III) complex with a tripodal tetraamine ligand, tpea = tris[2-(1-pyrazoyl)ethyl]amine, has been prepared and characterized in this article.
Journal ArticleDOI

Taurolidine cooperates with antineoplastic drugs in neuroblastoma cells.

Georg Eschenburg, +3 more
- 01 Nov 2014 - 
TL;DR: Application of TRD resulted in a significant enhancement of cytotoxic drugs vincristine/doxorubicin (2/3 of 4 cell lines) making TRD a promising candidate to be included in neuroblastoma therapy regimens in the future.
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Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness

Sukhontip Klahan, +9 more
- 01 Jan 2016 - 
TL;DR: A microarray analysis found that endothelin-1 (EDN1), dishevelled segment polarity protein (DV1), toll-like receptor 5(TLR5), mitogen-activated protein kinase 3 (MAP2K3), phosphatidylinositol-4,5-bisphosphate 3-kinase, and catalytic subunit beta (PIK3CB) were closely related to responsiveness to oxaliplatin treatment.
Journal ArticleDOI

Split calibration curve: an approach to avoid repeat analysis of the samples exceeding ULOQ

Sudipta Basu, +5 more
- 23 Oct 2012 - 
TL;DR: A split calibration curve approach is described, where sample dilution and repeat analysis can be avoided without compromising the quality and integrity of the data obtained and this is useful for the bioanalysis of toxicokinetic studies with wide dose ranges and studies where the sample volume is limited.
Journal ArticleDOI

Control of active B and L cathepsins in tissues of colorectal cancer using cystatins isolated from chicken egg proteins: in vitro studies.

Andrzej Hap, +7 more
- 16 Jan 2012 - 
TL;DR: Application of the inhibitors was found to inhibit activity of the enzymes which play a key role in tumor development and it is suggested that in future the inhibitors may provide a component of new generation drugs in the so-called inhibitor therapy.