Journal ArticleDOI
Anti-cancer drugs
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This article is published in Current Pharmaceutical Design.The article was published on 2005-03-31. It has received 882 citations till now. The article focuses on the topics: Introductory Journal Article.read more
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Journal ArticleDOI
The status of platinum anticancer drugs in the clinic and in clinical trials.
TL;DR: The status of platinum anticancer drugs currently approved for use, those undergoing clinical trials and those discontinued during clinical trials are updated, and the results in the context of where the field will develop over the next decade are discussed.
Journal ArticleDOI
Natural products to drugs: natural product derived compounds in clinical trials
Mark S. Butler,Mark S. Butler +1 more
TL;DR: Natural product and natural product-derived compounds that are being evaluated in clinical trials or are in registration (as at 31st December 2007) have been reviewed, as well as natural products for which clinical trials have been halted or discontinued since 2005.
Journal ArticleDOI
Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs)
John Ramage,A Ahmed,J Ardill,N.D.S. Bax,David J. Breen,Martyn Caplin,Pippa Corrie,J Davar,Albert Davies,Val Lewington,Tim Meyer,John Newell-Price,Graeme J. Poston,N. Reed,Andrea Rockall,William P. Steward,Rajesh V. Thakker,C. Toubanakis,Juan W. Valle,Caroline S. Verbeke,Ashley B. Grossman +20 more
TL;DR: These guidelines update previous guidance published in 2005 and have been revised by a group who are members of the UK and Ireland Neuroendocrine Tumour Society with endorsement from the clinical committees of the British Society of Gastroenterology and others.
Journal ArticleDOI
Cellular distribution and functions of P2 receptor subtypes in different systems.
TL;DR: This review is aimed at providing readers with a comprehensive reference article about the distribution and function of P2 receptors in all the organs, tissues, and cells in the body.
Journal ArticleDOI
Natural products: an evolving role in future drug discovery.
Bhuwan B. Mishra,Vinod K. Tiwari +1 more
TL;DR: The present review describes natural products, semi-synthetic NPs and NP-derived compounds that have undergone clinical evaluation or registration from 2005 to 2010 by disease area i.e. infectious, immunological, cardiovascular, neurological, inflammatory and related diseases and oncology.
References
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Formation of Human Telomeric G-quadruplex Structures Induced by the Quaternary Benzophenanthridine Alkaloids: Sanguinarine, Nitidine, and Chelerythrine
TL;DR: In this article, the interaction between single-strand human telomeric DNA and three quaternary benzophenanthridine alkaloids (QBAs), the very important G-quadruplex binders, has been investigated.
Book ChapterDOI
Dendrimers : Properties and Applications
TL;DR: This chapter provides a review of the use of various dendrimer families in drug-delivery applications and a brief introduction to the field of d endrimer science.
Journal ArticleDOI
Cancers of the Pancreas and Hepatobiliary System
TL;DR: While survival is slowly increasing, morbidity and mortality associated with hepatobiliary and pancreas cancers remains high and scientific study is needed to identify methods of detecting these malignancies earlier and to develop therapeutic approaches that will effectively decrease tumor burden.
Journal ArticleDOI
Alkylation of thiohydantoins including synthesis, conformational and configurational studies of some acetylated s-pyranosides
TL;DR: The Mannich reaction with formaldehyde and morpholine was used to give the corresponding Mannich products 2 and 7, respectively, for deacetylation of 2-thio and 2-dithiohydantoin derivatives.
Journal ArticleDOI
Optical characteristics of responsive biopolymers; co-polycondensation of tri-functional amino acids and Cy-3 bis-amine with diacylchlorides
TL;DR: It is shown that the free fluorophore can be used to probe the conformation of unlabelled poly( l -lysine iso-phthalamide) through electrostatic interaction with the polymer, and offers the potential of an environmentally sensitive molecular pH probe for in vivo use.