Journal ArticleDOI
Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation.
TLDR
In conclusion, CGA improved glucose and lipid metabolism, via the activation of AMPK, in Lepr(db/db) mice.About:
This article is published in Biochemical Pharmacology.The article was published on 2013-05-01. It has received 296 citations till now. The article focuses on the topics: AMPK & Glucose uptake.read more
Citations
More filters
Journal ArticleDOI
Phenolic acids: Natural versatile molecules with promising therapeutic applications.
Naresh Kumar,Nidhi Goel +1 more
TL;DR: Phenolic acids are key class of dietary polyphenols, natural antioxidants that shields against growth and evolution in pathological conditions arise from oxidative stress.
Journal ArticleDOI
The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: a comprehensive review of the literature
TL;DR: The effects of CGAs on different aspects of health by reviewing the related literatures have been discussed and it is postulated that CGA is able to exert pivotal roles on glucose and lipid metabolism regulation and on the related disorders, e.g. diabetes, cardiovascular disease (CVD), obesity, cancer, and hepatic steatosis.
Journal ArticleDOI
Roles of Chlorogenic Acid on Regulating Glucose and Lipids Metabolism: A Review
TL;DR: This review addresses current studies investigating the roles of CGA in glucose and lipid metabolism and indicates that CGA exerts many biological properties, including antibacterial, antioxidant, and anticarcinogenic activities.
Journal ArticleDOI
Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome.
TL;DR: The role of chlorogenic acid as a nutraceutical for the prevention and treatment of metabolic syndrome and associated disorders, including in vivo studies, clinical trials, and mechanisms of action is discussed.
Journal ArticleDOI
Anti-inflammatory effects of chlorogenic acid in lipopolysaccharide-stimulated RAW 264.7 cells.
TL;DR: Chlorogenic acid significantly inhibited not only NO production but also the expression of COX-2 and iNOS, without any cytotoxicity and inhibited the nuclear translocation of NF-κB.
References
More filters
Book
Methods of Enzymatic Analysis
TL;DR: Methods of enzymatic analysis, Methods of enzymes analysis, the authors, Methods of enzyme analysis, enzymatics, methods of enzymes, and methods of analysis, method of enzymes.
Journal ArticleDOI
Polyphenols: food sources and bioavailability
TL;DR: The nature and contents of the various polyphenols present in food sources and the influence of agricultural practices and industrial processes are reviewed, and bioavailability appears to differ greatly between the variousPolyphenols, and the most abundantpolyphenols in the authors' diet are not necessarily those that have the best bioavailability profile.
Journal ArticleDOI
Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients
Kikuko Hotta,Tohru Funahashi,Yukio Arita,Masahiko Takahashi,Morihiro Matsuda,Yoshihisa Okamoto,Hiromi Iwahashi,Hiroshi Kuriyama,Noriyuki Ouchi,Kazuhisa Maeda,Makoto Nishida,Shinji Kihara,Naohiko Sakai,Tadahisa Nakajima,Kyoichi Hasegawa,Masahiro Muraguchi,Yasukazu Ohmoto,Tadashi Nakamura,Shizuya Yamashita,Toshiaki Hanafusa,Yuji Matsuzawa +20 more
TL;DR: Results suggest that the decreased plasma adiponectin concentrations in diabetes may be an indicator of macroangiopathy, and weight reduction significantly elevated plasma adip onectin levels in the diabetic subjects as well as the nondiabetic subjects.
Journal ArticleDOI
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.
Kerry L. Donnelly,Coleman Smith,Sarah Jane Schwarzenberg,Jose Jessurun,Mark D. Boldt,Elizabeth J. Parks +5 more
TL;DR: In this article, the authors quantified the biological sources of hepatic and plasma lipoprotein TAG in NAFLD patients, using stable isotopes for four days to label and track serum nonesterified fatty acids (NEFAs), dietary fatty acids, and those derived from the de novo lipogenesis (DNL) pathway, present in liver tissue and lipid TAG.
Journal ArticleDOI
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
TL;DR: It is proposed that Acrp30 is a potent insulin enhancer linking adipose tissue and whole-body glucose metabolism, which triggers a transient decrease in basal glucose levels in mice treated with streptozotocin.