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Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE
Marc Humbert,Richard Beasley,J. Ayres +2 more
- pp 425-434
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The article was published on 2017-01-01 and is currently open access. It has received 848 citations till now. The article focuses on the topics: Omalizumab.read more
Citations
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Global strategy for asthma management and prevention: GINA executive summary.
Eric D. Bateman,Suzanne S. Hurd,Peter J. Barnes,Jean Bousquet,Jeffrey M. Drazen,JM FitzGerald,Peter G. Gibson,K. Ohta,Paul M. O'Byrne,Søren Pedersen,Emilio Pizzichini,Sean D. Sullivan,Sally E. Wenzel,Heather J. Zar +13 more
TL;DR: It is reasonable to expect that in most patients with asthma, control of the disease can and should be achieved and maintained, and the Global Initiative for Asthma recommends a change in approach to asthma management, with asthma control, rather than asthma severity, being the focus of treatment decisions.
Journal ArticleDOI
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Kian Fan Chung,Sally E. Wenzel,Jan Brozek,Andrew Bush,Mario Castro,Peter J. Sterk,Ian M. Adcock,Eric D. Bateman,Elisabeth H. Bel,Eugene R. Bleecker,Louis-Philippe Boulet,Christopher E. Brightling,Pascal Chanez,Sven-Erik Dahlén,Ratko Djukanovic,Urs Frey,Mina Gaga,Peter G. Gibson,Qutayba Hamid,Nizar N. Jajour,Thais Mauad,Ronald L. Sorkness,W. Gerald Teague +22 more
TL;DR: Recommendations and guidelines on the evaluation and treatment of severe asthma in children and adults and coordinated research efforts for improved phenotyping will provide safe and effective biomarker-driven approaches to severe asthma therapy are provided.
Journal ArticleDOI
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice.
Helen K. Reddel,D. Robin Taylor,Eric D. Bateman,Louis-Philippe Boulet,Homer A. Boushey,William W. Busse,Thomas B. Casale,Pascal Chanez,Paul L. Enright,Peter G. Gibson,Johan C. de Jongste,Huib A. M. Kerstjens,Stephen C. Lazarus,Mark L Levy,Paul M. O'Byrne,Martyn R Partridge,Ian D. Pavord,Malcolm R. Sears,Peter J. Sterk,Stuart W. Stoloff,Sean D. Sullivan,Stanley J. Szefler,Mike Thomas,Sally E. Wenzel +23 more
TL;DR: New definitions for asthma control, severity, and exacerbations are developed, based on current treatment principles and clinical and research relevance, to provide a basis for a multicomponent assessment of asthma by clinicians, researchers, and other relevant groups in the design, conduct, and evaluation of clinical trials, and in clinical practice.
Journal ArticleDOI
British guideline on the management of asthma: A national clinical guideline
Graham Douglas,Bernard Higgins,Neil Barnes,Anne Boyter,Sherwood Burge,Christopher J Cates,Gary Connett,Jon Couriel,Paul Cullinan,Sheila Edwards,Erica Evans,Monica Fletcher,Christopher E.M. Griffiths,Liam Heaney,Michele Hilton Boon,Steve Holmes,Ruth McArthur,C Nelson-Piercy,Martyn R Partridge,James Y. Paton,Ian D. Pavord,Elaine Carnegie,Hilary Pinnock,Safia Qureshi,Colin F. Robertson,Michael D. Shields,John O. Warner,John H. White +27 more
TL;DR: These guidelines have been replaced by British Guideline on the Management of Asthma.
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Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision
Jan Brozek,Jean Bousquet,Carlos E. Baena-Cagnani,Sergio Bonini,G. Walter Canonica,Thomas B. Casale,Roy Gerth van Wijk,Ken Ohta,Torsten Zuberbier,Holger J. Schünemann +9 more
TL;DR: These are the most recent and currently the most systematically and transparently developed recommendations about the treatment of allergic rhinitis in adults and children and patients are encouraged to use these recommendations in their daily practice and to support their decisions.
References
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Risk factors for recurrent asthma hospital visits and death among a population of indigent older adults with asthma
Tina V. Hartert,Theodore Speroff,Alkis Togias,Edward F. Mitchel,Mary Snowden,Robert S. Dittus,Marie R. Griffin +6 more
TL;DR: Asthma severity predicted both recurrent hospital visits and all-cause mortality among older adults with asthma requiring hospital care and was the strongest independent risk factor for both a recurrent hospital visit and death.
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Michael Leslie Burr,B. H. Davies,A. Hoare,A. Jones,I. J. Williamson,S. K. Holgate,R. Arthurs,I. G. C. Hodges +7 more
TL;DR: Investigation of deaths attributable to asthma in residents of Wales under the age of 65 years found some preventable asthma deaths still occur but, if doctors are aware of high risk patients, increased vigilance may prevent some deaths.
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Risk factors for asthma deaths: a population‐based, case‐control study
TL;DR: Investigation of risk factors for death from asthma using a case‐control study design with two control groups finds that smoking, alcohol and obesity are major predictors of death.
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Gold as an oral corticosteroid sparing agent in stable asthma.
David J. Evans,Paul Cullinan,Duncan M. Geddes,E. Haydn Walters,Stephen J Milan,Paul W. Jones +5 more
TL;DR: The effects of adding gold to oral steroids in the treatment of chronic steroid dependent asthmatics are assessed and necessity for monitoring the use of gold as a steroid sparing agent in asthma cannot be recommended.
Journal Article
Erratum: The anti-IgE antibody omalizumab reduces exacerbations and steroid requirement in allergic asthmatics (European Respiratory Journal (2001) vol. 18 (254-261))
Markus Solèr,J. Matz,Robert G. Townley,Roland Buhl,J. O'Brien,Howard Fox,Jackie Thirlwell,Niroo Gupta,G. Della Cioppa +8 more