Cancer statistics, 2016
Reads0
Chats0
TLDR
Overall cancer incidence trends are stable in women, but declining by 3.1% per year in men, much of which is because of recent rapid declines in prostate cancer diagnoses, and brain cancer has surpassed leukemia as the leading cause of cancer death among children and adolescents.Abstract:
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival. Incidence data were collected by the National Cancer Institute (Surveillance, Epidemiology, and End Results [SEER] Program), the Centers for Disease Control and Prevention (National Program of Cancer Registries), and the North American Association of Central Cancer Registries. Mortality data were collected by the National Center for Health Statistics. In 2016, 1,685,210 new cancer cases and 595,690 cancer deaths are projected to occur in the United States. Overall cancer incidence trends (13 oldest SEER registries) are stable in women, but declining by 3.1% per year in men (from 2009-2012), much of which is because of recent rapid declines in prostate cancer diagnoses. The cancer death rate has dropped by 23% since 1991, translating to more than 1.7 million deaths averted through 2012. Despite this progress, death rates are increasing for cancers of the liver, pancreas, and uterine corpus, and cancer is now the leading cause of death in 21 states, primarily due to exceptionally large reductions in death from heart disease. Among children and adolescents (aged birth-19 years), brain cancer has surpassed leukemia as the leading cause of cancer death because of the dramatic therapeutic advances against leukemia. Accelerating progress against cancer requires both increased national investment in cancer research and the application of existing cancer control knowledge across all segments of the population.read more
Citations
More filters
Journal ArticleDOI
Colorectal Cancer Incidence Patterns in the United States, 1974-2013.
Rebecca L. Siegel,Stacey A. Fedewa,William F. Anderson,Kimberly D. Miller,Jiemin Ma,Philip S. Rosenberg,Ahmedin Jemal +6 more
TL;DR: Age-specific CRC risk has escalated back to the level of those born circa 1890 for contemporary birth cohorts, underscoring the need for increased awareness among clinicians and the general public, as well as etiologic research to elucidate causes for the trend.
Journal ArticleDOI
Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
Jennifer S Lin,Margaret Piper,Leslie A Perdue,Carolyn M. Rutter,Carolyn M. Rutter,Elizabeth M. Webber,Elizabeth O'Connor,Ning Smith,Evelyn P Whitlock +8 more
TL;DR: In randomized trials conducted among average-risk, asymptomatic women, ovarian cancer mortality did not significantly differ between screened women and those with no screening or in usual care; evidence on psychological harms was limited but nonsignificant.
Journal ArticleDOI
Liver macrophages in tissue homeostasis and disease
Oliver Krenkel,Frank Tacke +1 more
TL;DR: Novel findings regarding the origin, classification and function of hepatic macrophages are highlighted, and their divergent roles in the healthy and diseased liver are discussed.
Journal ArticleDOI
Systemic Therapy for Metastatic Renal-Cell Carcinoma.
TL;DR: The 5-year survival rate among patients with kidney cancer increased from 57% in 1987−1989 to 74% in 2006−20121; this increase was attributable in part to a higher proportion of indolent and low-stage tumors identified using improved early-detection techniques.
Journal ArticleDOI
Previous radiotherapy and the clinical activity and toxicity of pembrolizumab in the treatment of non-small-cell lung cancer: a secondary analysis of the KEYNOTE-001 phase 1 trial
Narek Shaverdian,Aaron Lisberg,Krikor Bornazyan,Darlene Veruttipong,Jonathan W. Goldman,Silvia C. Formenti,Edward B. Garon,Percy Lee +7 more
TL;DR: This trial aimed to assess disease control and pulmonary toxicity in patients who previously received radiotherapy for non-small-cell lung cancer (NSCLC) before receiving pembrolizumab to determine whether previous radiotherapy affected progression-free survival, overall survival, and pulmonaryoxicity in the intention-to-treat population.
References
More filters
Journal ArticleDOI
Reduced lung-cancer mortality with low-dose computed tomographic screening.
Denise R. Aberle,Amanda M. Adams,Christine D. Berg,William C. Black,Jonathan D. Clapp,Richard M. Fagerstrom,Ilana F. Gareen,Constantine Gatsonis,Pamela M. Marcus,JoRean D. Sicks +9 more
TL;DR: Screening with the use of low-dose CT reduces mortality from lung cancer, as compared with the radiography group, and the rate of death from any cause was reduced.
SEER Cancer Statistics Review, 1975-2003
Lynn A. G. Ries,D. Harkins,Martin Krapcho,Angela B. Mariotto,Barry A. Miller,Eric J. Feuer,Limin X. Clegg,M. P. Eisner,Marie-Josèphe Horner,Nadia Howlader,Matthew J. Hayat,Benjamin F. Hankey,Brenda K. Edwards +12 more
The Health consequences of smoking—50 years of progress : a report of the Surgeon General
TL;DR: The scientific evidence is incontrovertible: inhaling tobacco smoke, particularly from cigarettes, is deadly.
Journal ArticleDOI
Permutation tests for joinpoint regression with applications to cancer rates
TL;DR: A joinpoint regression model is applied to describe continuous changes in the recent trend and the grid-search method is used to fit the regression function with unknown joinpoints assuming constant variance and uncorrelated errors.
Book
International Classification of Diseases for Oncology
TL;DR: This list of diseases for oncology includes cancers of the central nervous system, as well as other types of diseases such as lymphoma, leukaemia, and so on.