Cancer statistics, 2016
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TLDR
Overall cancer incidence trends are stable in women, but declining by 3.1% per year in men, much of which is because of recent rapid declines in prostate cancer diagnoses, and brain cancer has surpassed leukemia as the leading cause of cancer death among children and adolescents.Abstract:
Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths that will occur in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival. Incidence data were collected by the National Cancer Institute (Surveillance, Epidemiology, and End Results [SEER] Program), the Centers for Disease Control and Prevention (National Program of Cancer Registries), and the North American Association of Central Cancer Registries. Mortality data were collected by the National Center for Health Statistics. In 2016, 1,685,210 new cancer cases and 595,690 cancer deaths are projected to occur in the United States. Overall cancer incidence trends (13 oldest SEER registries) are stable in women, but declining by 3.1% per year in men (from 2009-2012), much of which is because of recent rapid declines in prostate cancer diagnoses. The cancer death rate has dropped by 23% since 1991, translating to more than 1.7 million deaths averted through 2012. Despite this progress, death rates are increasing for cancers of the liver, pancreas, and uterine corpus, and cancer is now the leading cause of death in 21 states, primarily due to exceptionally large reductions in death from heart disease. Among children and adolescents (aged birth-19 years), brain cancer has surpassed leukemia as the leading cause of cancer death because of the dramatic therapeutic advances against leukemia. Accelerating progress against cancer requires both increased national investment in cancer research and the application of existing cancer control knowledge across all segments of the population.read more
Citations
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Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer
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Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer
Guangbo Liu,Fen Pei,Fengqing Yang,Lingxiao Li,Amit Dipak Amin,Songnian Liu,J. Ross Buchan,William C. Cho +7 more
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Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That Overexpress Human Epidermal Growth Factor Receptor 2/neu
Amanda N. Fader,Dana M. Roque,Eric R. Siegel,Natalia Buza,Pei Hui,Osama Abdelghany,Setsuko K. Chambers,Angeles Alvarez Secord,Laura J. Havrilesky,David M. O'Malley,Floor J. Backes,Nicole S. Nevadunsky,Babak Edraki,Dirk Pikaart,William J. Lowery,K. ElSahwi,Paul Celano,Stefania Bellone,Masoud Azodi,Babak Litkouhi,Elena Ratner,Dan-Arin Silasi,Peter E. Schwartz,Alessandro D. Santin +23 more
TL;DR: Addition of trastuzumab to carboplatin-paclitaxel was well tolerated and increased progression-free survival, and no unexpected safety signals emerged.
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Risk of Neoplastic Progression in Individuals at High Risk for Pancreatic Cancer Undergoing Long-term Surveillance
Marcia I. Canto,Jose Alejandro Almario,Richard D. Schulick,Charles J. Yeo,Alison P. Klein,Amanda L. Blackford,Eun Ji Shin,Abanti Sanyal,Gayane Yenokyan,Anne Marie Lennon,Ihab R. Kamel,Elliot K. Fishman,Christopher L. Wolfgang,Matthew J. Weiss,Ralph H. Hruban,Michael Goggins +15 more
TL;DR: In a long-term (16-year) follow-up study of individuals at high-risk for PDAC, most PDACs detected during surveillance were found to be resectable, and 85% of patients survived for 3 years.
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Glycans and glycoproteins as specific biomarkers for cancer
TL;DR: This review highlights some of the efforts being made to identify N- and O-glycosylation profile shifts in cancer using mass spectrometry, including the analysis of single or panels of potential glycoprotein cancer markers.
References
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Book
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TL;DR: This list of diseases for oncology includes cancers of the central nervous system, as well as other types of diseases such as lymphoma, leukaemia, and so on.