Center-surround interactions underlie bipolar cell motion sensitivity in the mouse retina
Sarah Strauss,Maria M. Korympidou,Yanli Ran,Katrin Franke,Timm Schubert,Tom Baden,Philipp Berens,Thomas Euler,Anna Vlasits +8 more
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In this article , the authors studied the representation of motion in mouse retinal bipolar cells and found that some bipolar cells are radially direction selective, preferring the origin of small object motion trajectories.Abstract:
Motion sensing is a critical aspect of vision. We studied the representation of motion in mouse retinal bipolar cells and found that some bipolar cells are radially direction selective, preferring the origin of small object motion trajectories. Using a glutamate sensor, we directly observed bipolar cells synaptic output and found that there are radial direction selective and non-selective bipolar cell types, the majority being selective, and that radial direction selectivity relies on properties of the center-surround receptive field. We used these bipolar cell receptive fields along with connectomics to design biophysical models of downstream cells. The models and additional experiments demonstrated that bipolar cells pass radial direction selective excitation to starburst amacrine cells, which contributes to their directional tuning. As bipolar cells provide excitation to most amacrine and ganglion cells, their radial direction selectivity may contribute to motion processing throughout the visual system. read more
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Classical center-surround receptive fields facilitate novel object detection in retinal bipolar cells
TL;DR: In this paper , the authors found that bipolar glutamate release emphasizes objects that emerge in the receptive field (RF) during continuous motion, and that the alteration in signal dynamics induced by novel objects was more pronounced than edge enhancement.
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Spatiotemporal properties of glutamate input support direction selectivity in the dendrites of retinal starburst amacrine cells
TL;DR: In this article , the authors used two-photon glutamate sensor (iGluSnFR) imaging to directly measure the input kinetics across individual starburst dendrites.
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Spatiotemporal properties of glutamate input support direction selectivity in the dendrites of retinal starburst amacrine cells
Prerna Srivastava,Geoffery deRosenroll,Benjamin L. Murphy-Baum,Tracy Michaels,Akihiro Matsumoto,Keisuke Yonehara,Gautam B. Awatramani +6 more
TL;DR: Using a connectomics-inspired computational model, it is demonstrated that input kinetics play an important role in shaping direction selectivity at low stimulus velocities and provides direct support for the ‘space-time wiring’ model for directionSelectivity.
Journal ArticleDOI
Hierarchical retinal computations rely on hybrid chemical-electrical signaling.
TL;DR: In this paper , the authors demonstrate orientation selectivity in a specific genetically identifiable type of mouse bipolar cell-type 5A (BC5A), which responds best when stimulated with vertical bars that are far larger than their dendritic fields.
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The coherent organization of dynamic visual images
Joseph S. Lappin,Herbert H. Bell +1 more
TL;DR: In this article , the authors review converging psychophysical and physiological evidence about the structure and precision of the perceived spatiotemporal organization of dynamic images and find that visual acuity, temporal resolution, and contrast sensitivity have been found to involve motion-produced increases in image contrast, coherent phase relations among temporally varying retinal signals, and physiological preservation of spatio-temporal structure from retina to cortex.
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