Journal ArticleDOI
Conn: A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
TLDR
The results indicate that the CompCor method increases the sensitivity and selectivity of fcMRI analysis, and show a high degree of interscan reliability for many fc MRI measures.Citations
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The devil is in the detail: exploring the intrinsic neural mechanisms that link attention-deficit/hyperactivity disorder symptomatology to ongoing cognition.
TL;DR: The results of this study suggest that the frequent mind-wandering observed in ADHD may be an indirect consequence of the deficient control of ongoing cognition in response to increasing environmental demands, and that this may partly arise from dysfunctions in the intrinsic organisation of the FPN at rest.
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Lower limb amputees undergo long-distance plasticity in sensorimotor functional connectivity.
Ivanei E. Bramati,Erika de Carvalho Rodrigues,Elington Lannes Simões,Bruno F. Melo,Sebastian Höfle,Jorge Moll,Roberto Lent,Fernanda Tovar-Moll +7 more
TL;DR: Functional connectivity changes in specialized small-scale sensory-motor networks improve the understanding of the functional impact of lower limb amputation in the brain and step up the description of brain plasticity related with phantom sensations by showing that pain is not critical for sensorimotor network changes after peripheral injury.
Journal ArticleDOI
Network-wide abnormalities explain memory variability in hippocampal amnesia
Georgios P. D. Argyropoulos,Clare Loane,Clare Loane,Adriana Roca-Fernandez,Carmen Lage-Martinez,Oana Gurau,Sarosh R. Irani,Christopher C Butler +7 more
TL;DR: It is hypothesized that focal hippocampal damage is associated with changes across the extended hippocampal system and that these, rather than hippocampal atrophy per se, would explain variability in memory between patients.
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Thalamocortical integration of instrumental learning and performance and their disintegration in addiction
TL;DR: In this paper, the authors hypothesize that these changes result from a core deficit in the way the learning and performance factors that support goal-directed action are integrated at a neural level to maintain behavioral control, and that disintegration in this network may provide the basis for a'switch' from recreational to dysregulated drug seeking.
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Distinct cortico-striatal connections with subthalamic nucleus underlie facets of compulsivity.
TL;DR: This work characterized the relationship between measures of compulsivity (goal-directed and habit learning, perseveration, and self-reported obsessive – compulsive symptoms) and the intrinsic resting state network of the subthalamic nucleus (STN) and highlighted unique contributions of diffuse cortico-striatal functional connections with STN in dissociable measures of compulsion.
References
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Journal ArticleDOI
Collective dynamics of small-world networks
TL;DR: Simple models of networks that can be tuned through this middle ground: regular networks ‘rewired’ to introduce increasing amounts of disorder are explored, finding that these systems can be highly clustered, like regular lattices, yet have small characteristic path lengths, like random graphs.
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A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
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Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.