Journal ArticleDOI
Conn: A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
TLDR
The results indicate that the CompCor method increases the sensitivity and selectivity of fcMRI analysis, and show a high degree of interscan reliability for many fc MRI measures.Citations
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Increased neural connectivity between the hypothalamus and cortical resting-state functional networks in chronic migraine
Gianluca Coppola,Antonio Di Renzo,Barbara Petolicchio,Emanuele Tinelli,Cherubino Di Lorenzo,Mariano Serrao,Valentina Calistri,Stefano Tardioli,Gaia Cartocci,Vincenzo Parisi,Francesca Caramia,Vittorio Di Piero,Francesco Pierelli +12 more
TL;DR: Investigating the functional connectivity between the hypothalamus, brainstem, and the following areas/networks that are reportedly involved in the pathophysiology of migraine found evidence for hypothalamic involvement in large-scale reorganisation at the functional-network level in CM and in proportion with the perceived severity of the migraine pain.
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Neural Plasticity of Mild Tinnitus: An fMRI Investigation Comparing Those Recently Diagnosed with Tinnitus to Those That Had Tinnitus for a Long Period of Time.
TL;DR: The results suggest that the posterior cingulate and insula may be associated with an early emotional reaction to tinnitus in both task and resting states and may recruit more frontal regions to better control their emotional response and exhibit altered connectivity in the default mode network.
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A comparison of functional and tractography based networks in cerebral small vessel disease.
TL;DR: Structural networks identify impaired network integrity, and are highly reproducible, in SVD, supporting their use as markers of SVD disease severity, compared to functional networks, which showed low reproducibility.
Journal ArticleDOI
Altered Functional Connectivity of the Basal Nucleus of Meynert in Mild Cognitive Impairment: A Resting-State fMRI Study.
TL;DR: MCI is associated with changes in BNM-FC to the insula/claustrum in relation to cognitive impairments, which may advance research of the cholinergic bases of cognitive dysfunction during healthy aging and in individuals at risk of developing Alzheimer’s disease.
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Switching between internally and externally focused attention in obsessive-compulsive disorder: Abnormal visual cortex activation and connectivity
Emily R. Stern,Alexandra F. Muratore,Stephan F. Taylor,James L. Abelson,Patrick R. Hof,Wayne K. Goodman +5 more
TL;DR: Findings point to an OCD-related impairment in the visual processing of external stimuli specifically when they follow a period of negative internal focus, and suggest that future treatments may wish to target the transition between attentional states.
References
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Journal ArticleDOI
Collective dynamics of small-world networks
TL;DR: Simple models of networks that can be tuned through this middle ground: regular networks ‘rewired’ to introduce increasing amounts of disorder are explored, finding that these systems can be highly clustered, like regular lattices, yet have small characteristic path lengths, like random graphs.
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A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
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Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.