Journal ArticleDOI
Conn: A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
TLDR
The results indicate that the CompCor method increases the sensitivity and selectivity of fcMRI analysis, and show a high degree of interscan reliability for many fc MRI measures.Citations
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Acute ketamine challenge increases resting state prefrontal-hippocampal connectivity in both humans and rats.
Oliver Grimm,Natalia Gass,Wolfgang Weber-Fahr,Alexander Sartorius,Esther Schenker,Michael Spedding,Celine Risterucci,Janina I. Schweiger,Andreas Böhringer,Zhenxiang Zang,Heike Tost,Adam J. Schwarz,Adam J. Schwarz,Andreas Meyer-Lindenberg +13 more
TL;DR: This translational comparison demonstrates a cross-species consistency in pharmacological effect and elucidates ketamine-induced alterations in PFC-HC coupling, a phenotype often disrupted in pathological conditions, which may give clue to understanding of psychiatric disorders and their onset, and help in the development of new treatments.
Journal ArticleDOI
Sex and Disease-Related Alterations of Anterior Insula Functional Connectivity in Chronic Abdominal Pain
Jui-Yang Hong,Lisa A. Kilpatrick,Jennifer S. Labus,Arpana Gupta,David Katibian,Cody Ashe-McNalley,Jean Stains,Nuwanthi Heendeniya,Suzanne R. Smith,Kirsten Tillisch,Bruce D. Naliboff,Emeran A. Mayer +11 more
TL;DR: Comparisons of functional connectivity of the dorsal anterior INS in age-matched female and male healthy subjects and patients with irritable bowel syndrome show that this role is influenced by sex and diagnosis, consistent with the INS playing an important role in modulating the intrinsic functional connectivity in the resting brain.
Journal ArticleDOI
Mind-body exercise improves cognitive function and modulates the function and structure of the hippocampus and anterior cingulate cortex in patients with mild cognitive impairment.
Jing Tao,Jiao Liu,Xiangli Chen,Rui Xia,Moyi Li,Maomao Huang,Shuzhen Li,Joel Park,Georgia Wilson,Courtney Lang,Guanli Xie,Binlong Zhang,Guohua Zheng,Lidian Chen,Jian Kong +14 more
TL;DR: The results demonstrate the potential of Baduanjin for the treatment of MCI and show decreased ALFF value changes in the right hippocampus and bilateral ACC were significantly associated with corresponding MoCA score changes across all groups.
Journal ArticleDOI
Resting-state functional connectivity of the human habenula in healthy individuals: Associations with subclinical depression.
TL;DR: High and low subclinical depression groups exhibited differences in Hb connectivity with multiple regions previously linked to depression, suggesting the relationship between these structures as a potential target for future research and treatment.
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Alterations of amygdala-prefrontal connectivity with real-time fMRI neurofeedback in BPD patients
Christian Paret,Rosemarie Kluetsch,Jenny Zaehringer,Matthias Ruf,Traute Demirakca,Martin Bohus,Gabriele Ende,Christian Schmahl +7 more
TL;DR: It is demonstrated that amygdala NF may improve healthy brain connectivity, as well as emotion regulation in patients with borderline personality disorder and a randomized-controlled trial is needed to investigate whether amygdala NF is instrumental for improving neural regulation and emotionregulation in BPD patients.
References
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Journal ArticleDOI
Collective dynamics of small-world networks
TL;DR: Simple models of networks that can be tuned through this middle ground: regular networks ‘rewired’ to introduce increasing amounts of disorder are explored, finding that these systems can be highly clustered, like regular lattices, yet have small characteristic path lengths, like random graphs.
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A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
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Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.