Journal ArticleDOI
Conn: A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
TLDR
The results indicate that the CompCor method increases the sensitivity and selectivity of fcMRI analysis, and show a high degree of interscan reliability for many fc MRI measures.Citations
More filters
Journal ArticleDOI
Atypical behaviour and connectivity in SHANK3-mutant macaques.
Yang Zhou,Yang Zhou,Yang Zhou,Jitendra Sharma,Qiong Ke,Rogier Landman,Rogier Landman,Jingli Yuan,Hong Chen,David S. Hayden,John W. Fisher,Minqing Jiang,William Menegas,Tomomi Aida,Ting Yan,Ying Zou,Dongdong Xu,Shivangi Parmar,Shivangi Parmar,Julia B. Hyman,Julia B. Hyman,Adrian Fanucci-Kiss,Adrian Fanucci-Kiss,Olivia Meisner,Olivia Meisner,Dongqing Wang,Dongqing Wang,Yan Huang,Yaqing Li,Bai Yanyang,Ji Wenjing,Xinqiang Lai,Weiqiang Li,Lihua Huang,Zhonghua Lu,Liping Wang,Sheeba Arnold Anteraper,Sheeba Arnold Anteraper,Mriganka Sur,Mriganka Sur,Huihui Zhou,Andy Peng Xiang,Robert Desimone,Robert Desimone,Guoping Feng,Guoping Feng,Guoping Feng,Shihua Yang +47 more
TL;DR: The CRISPR–Cas9-mediated generation of germline-transmissible mutations of SHANK3 in cynomolgus macaques (Macaca fascicularis) forms the basis of a non-human-primate model of autism spectrum disorder and Phelan–McDermid syndrome.
Journal ArticleDOI
BRAPH: A graph theory software for the analysis of brain connectivity.
TL;DR: A freeware MatLab-based software (BRAPH–BRain Analysis using graPH theory) for connectivity analysis of brain networks derived from structural magnetic resonance imaging (MRI), functional MRI (fMRI), positron emission tomography and electroencephalogram (EEG) data.
Journal ArticleDOI
Consciousness-specific dynamic interactions of brain integration and functional diversity.
Andrea I. Luppi,Michael M. Craig,Ioannis Pappas,Ioannis Pappas,Paola Finoia,Guy B. Williams,Judith Allanson,John D. Pickard,Adrian M. Owen,Lorina Naci,David K. Menon,Emmanuel Stamatakis +11 more
TL;DR: The authors show that anaesthetised individuals and patients with disorders of consciousness exhibit overlapping reductions in both diversity and integration in the brain’s default mode network, showing that human consciousness relies on spatio-temporal interactions between brain integration and functional diversity.
Journal ArticleDOI
Graph theory approaches to functional network organization in brain disorders: A critique for a brave new small-world.
TL;DR: A review of clinical network neuroscience, summarizing methodological details from 106 RSFC studies and offering suggestions for promoting convergence across clinical studies in order to facilitate progress in this important field.
Journal ArticleDOI
Aberrant Coupling Within and Across the Default Mode, Task-Positive, and Salience Network in Subjects at Risk for Psychosis
Diana Wotruba,Lars Michels,Roman Buechler,Sibylle Metzler,Anastasia Theodoridou,Miriam Gerstenberg,Susanne Walitza,Spyros Kollias,Wulf Rössler,Karsten Heekeren +9 more
TL;DR: It is proposed that the loss of a TPN-DMN anticorrelation, accompanied by an aberrant spatial extent in the DMN, TPN, and SN in the psychosis risk state, reflects the confusion of internally and externally focused states and disturbance of cognition, as seen in psychotic disorders.
References
More filters
Journal ArticleDOI
Collective dynamics of small-world networks
TL;DR: Simple models of networks that can be tuned through this middle ground: regular networks ‘rewired’ to introduce increasing amounts of disorder are explored, finding that these systems can be highly clustered, like regular lattices, yet have small characteristic path lengths, like random graphs.
Journal ArticleDOI
A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
Journal ArticleDOI
Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
Journal ArticleDOI
Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
Journal ArticleDOI
The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.