Journal ArticleDOI
Conn: A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
TLDR
The results indicate that the CompCor method increases the sensitivity and selectivity of fcMRI analysis, and show a high degree of interscan reliability for many fc MRI measures.Citations
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Network diffusion accurately models the relationship between structural and functional brain connectivity networks.
TL;DR: A properly designed linear model appears to be superior to previous non-linear approaches in capturing the brain's long-range second order correlation structure that governs the relationship between anatomic and functional connectivities, and can routinely be used to infer functional correlation from anatomic connectivity.
Journal ArticleDOI
Age differences in the functional interactions among the default, frontoparietal control, and dorsal attention networks
TL;DR: The link between age differences in inter-network connections of the FPC and DMN connectivity, and the link between FPC connectivity and performance, support the hypothesis that FC ofThe FPC influences the expression of age Differences in other networks, as well as differences in cognitive function.
Journal ArticleDOI
Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients
Athena Demertzi,Georgios Antonopoulos,Lizette Heine,Henning U. Voss,Julia Sophia Crone,Carlo de los Angeles,Mohamed Ali Bahri,Carol Di Perri,Audrey Vanhaudenhuyse,Vanessa Charland-Verville,Martin Kronbichler,Eugen Trinka,Christophe Phillips,Francisco Gómez,Luaba Tshibanda,Andrea Soddu,Nicholas D. Schiff,Susan Whitfield-Gabrieli,Steven Laureys +18 more
TL;DR: The findings point to the significance of preserved abilities for multisensory integration and top-down processing in minimal consciousness seemingly supported by auditory-visual crossmodal connectivity, and promote the clinical utility of the resting paradigm for single-patient diagnostics.
Journal ArticleDOI
Separate neural representations for physical pain and social rejection
Choong-Wan Woo,Leonie Koban,Ethan Kross,Martin A. Lindquist,Marie T. Banich,Luka Ruzic,Jessica R. Andrews-Hanna,Tor D. Wager +7 more
TL;DR: It is demonstrated that separate representations underlie pain and rejection despite common fMRI activity at the gross anatomical level, rather than co-opting pain circuitry, rejection involves distinct affective representations in humans.
Journal ArticleDOI
Altered cerebellar connectivity in autism and cerebellar-mediated rescue of autism-related behaviors in mice
Catherine J. Stoodley,Anila M. D'Mello,Jacob Ellegood,Vikram Jakkamsetti,Pei Liu,Mary Beth Nebel,Jennifer M. Gibson,Elyza Kelly,Fan-Tao Meng,Christopher A. Cano,Juan M. Pascual,Stewart H. Mostofsky,Jason P. Lerch,Peter T. Tsai +13 more
TL;DR: This paper showed that chemogenetically mediated inhibition of RCrusI PN activity in mice was sufficient to generate ASD-related social, repetitive, and restricted behaviors, while stimulation of RcrusI PI PNs rescued social impairment in the Purkinje neuron (PN) TscI ASD mouse model.
References
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Journal ArticleDOI
Collective dynamics of small-world networks
TL;DR: Simple models of networks that can be tuned through this middle ground: regular networks ‘rewired’ to introduce increasing amounts of disorder are explored, finding that these systems can be highly clustered, like regular lattices, yet have small characteristic path lengths, like random graphs.
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A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
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Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.