Journal ArticleDOI
Conn: A Functional Connectivity Toolbox for Correlated and Anticorrelated Brain Networks
TLDR
The results indicate that the CompCor method increases the sensitivity and selectivity of fcMRI analysis, and show a high degree of interscan reliability for many fc MRI measures.Citations
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Integration and Segregation of Default Mode Network Resting-State Functional Connectivity in Transition-Age Males with High-Functioning Autism Spectrum Disorder: A Proof-of-Concept Study
Sheeba Arnold Anteraper,Kaustubh R. Patil,Meha Semwal,Rachel L. Goldin,Stephannie L. Furtak,Xiaoqian Jenny Chai,Zeynep M. Saygin,Joseph Biederman,Gagan Joshi,John D. E. Gabrieli,Susan Whitfield-Gabrieli +10 more
TL;DR: In this paper, Resting-state functional connectivity (RsFc) profile of the default mode network (DMN) in transition-age males with autism spectrum disorder (ASD) was assessed by assessing the positive and negative correlations of an average of the literature-based conceptualized major DMN nodes.
Journal ArticleDOI
Functional Connectivity Anomalies in Adolescents with Psychotic Symptoms
Francesco Amico,Erik O'Hanlon,Erik O'Hanlon,Dominik Kraft,Viola Oertel-Knöchel,Mary Clarke,Ian Kelleher,Niamh M. Higgins,Helen Coughlan,Daniel Creegan,Mark Heneghan,Emmet Power,Lucy Power,Jessica Ryan,Thomas Frodl,Mary Cannon +15 more
TL;DR: It is suggested that young adolescents with subclinical psychotic symptoms exhibit functional connectivity anomalies directly and indirectly involving the DMN, SN, CEN and also a neural network including both primary and secondary auditory cortical regions.
Journal ArticleDOI
The role of anxiety in stuttering: Evidence from functional connectivity.
TL;DR: This is the first study to examine the neural underpinnings of anxiety in PWS, thus yielding new insight into the causes of stuttering which might aid strategies for the diagnosis and treatment of stuttered.
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Altered frontal and insular functional connectivity as pivotal mechanisms for apathy in Alzheimer's disease.
Sarah Amy Jones,Matteo De Marco,Riccardo Manca,Simon M Bell,Daniel Blackburn,Iain D. Wilkinson,Hilkka Soininen,Annalena Venneri +7 more
TL;DR: The findings support a role of frontal and insular connections in coordinating value-based decisions in AD and both down-regulation and maladaptive up-regulation mechanisms appear to be at play in these regions.
Journal ArticleDOI
Association of Prenatal Acetaminophen Exposure Measured in Meconium With Risk of Attention-Deficit/Hyperactivity Disorder Mediated by Frontoparietal Network Brain Connectivity.
Brennan H. Baker,Claudia Lugo-Candelas,Claudia Lugo-Candelas,Haotian Wu,Hannah E. Laue,Amélie Boivin,Virginie Gillet,Natalie Aw,Tonima Rahman,Jean-François Lepage,Kevin Whittingstall,Jean-Philippe Bellenger,Jonathan Posner,Jonathan Posner,Larissa Takser,Andrea A. Baccarelli +15 more
TL;DR: Causal mediation analysis was used to test for mediation of the association between prenatal acetaminophen exposure and hyperactivity by resting-state brain connectivity, and this work suggests caution should be used in administeringacetaminophen during pregnancy.
References
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Journal ArticleDOI
Collective dynamics of small-world networks
TL;DR: Simple models of networks that can be tuned through this middle ground: regular networks ‘rewired’ to introduce increasing amounts of disorder are explored, finding that these systems can be highly clustered, like regular lattices, yet have small characteristic path lengths, like random graphs.
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A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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Complex brain networks: graph theoretical analysis of structural and functional systems
Edward T. Bullmore,Olaf Sporns +1 more
TL;DR: This article reviews studies investigating complex brain networks in diverse experimental modalities and provides an accessible introduction to the basic principles of graph theory and highlights the technical challenges and key questions to be addressed by future developments in this rapidly moving field.
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Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
Journal ArticleDOI
The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.