Journal ArticleDOI
Cooperative study in the evaluation of therapy in multiple sclerosis. ACTH vs. placebo--final report.
Augustus S. Rose,Jan W. Kuzma,John F. Kurtzke,Norman S. Namerow,William A. Sibley,Wallace W. Tourtellotte +5 more
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This article is published in Neurology.The article was published on 1970-05-01. It has received 252 citations till now. The article focuses on the topics: Placebo & Clinical trial.read more
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Journal ArticleDOI
Immunotherapy for multiple sclerosis.
TL;DR: The time is ripe to review how far recent trials should influence neurological practice, and the appearance of novel immunomodulatory agents bring worthwhile treatment a step nearer.
Journal ArticleDOI
Practice parameter: the role of corticosteroids in the management of acute monosymptomatic optic neuritis. report Of the quality standards subcommittee of the american academy of neurology(1)
TL;DR: Monosymptomatic acute ON is not rare and because the usefulness of oral prednisone in this disorder has recently been questioned, this practice parameter was developed to provide recommendations regarding the management of this common neurologic problem.
Journal ArticleDOI
Clinical and Economic Evaluation of Repository Corticotropin Injection: A Narrative Literature Review of Treatment Efficacy and Healthcare Resource Utilization for Seven Key Indications.
TL;DR: The evidence suggests that RCI may improve inflammatory and autoimmune disease control and patient quality of life, particularly in complex patients, and yield healthcare cost savings that demonstrate the medicine’s value.
Journal ArticleDOI
Assessing relapses and response to relapse treatment in patients with multiple sclerosis: a nursing perspective.
TL;DR: A brief but comprehensive objective assessment tool that can be used in practice to help clinicians assess patients when they present with symptoms of a relapse, and evaluate outcomes of acute management is described.
Journal ArticleDOI
Cyclophosphamide in exacerbations of multiple sclerosis. Therapeutic trial and a strategy for pilot drug studies.
TL;DR: A clinical trial of CY in acute MS exacerbations was undertaken, and the 'sequential criterion' method was used to minimize the size of sample needed for this pilot study.
Related Papers (5)
A Randomized, Controlled Trial of Corticosteroids in the Treatment of Acute Optic Neuritis
Roy W. Beck,Patricia A. Cleary,Malcolm M. Anderson,John L. Keltner,William T. Shults,David I. Kaufman,Edward G. Buckley,James J. Corbett,Mark J. Kupersmith,Neil R. Miller,Peter J. Savino,John Guy,Jonathan D. Trobe,John A. McCrary,Craig H. Smith,Georgia A. Chrousos,H. Stanley Thompson,Barrett Katz,Michael C. Brodsky,James Goodwin,Constance W. Atwell +20 more