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Journal ArticleDOI

Cooperative study in the evaluation of therapy in multiple sclerosis. ACTH vs. placebo--final report.

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This article is published in Neurology.The article was published on 1970-05-01. It has received 252 citations till now. The article focuses on the topics: Placebo & Clinical trial.

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Journal ArticleDOI

Immunosuppressive Treatment of Multiple Sclerosis

TL;DR: No firm guidelines for the treatment of chronic progressive multiple sclerosis can be offered, but an approach to immunosuppressive therapy is suggested in this review.
Journal ArticleDOI

Immunological treatment of multiple sclerosis

TL;DR: Immunosuppressive treatment of multiple sclerosis is based on the autoimmune hypothesis for which the main evidence is the close histological similarity between the human disease and chronic relapsing EAE, and controlled trials indicate that ACTH and oral steroids are ineffective.
Journal Article

A double-blind trial of transfer factor vs placebo in multiple sclerosis patients.

TL;DR: Of interest was the finding that the presence of the DW2 antigen, when unassociated with HLA-B7 antigen, appeared to correlate with the mildest form of disease activity.
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