Journal ArticleDOI
Cooperative study in the evaluation of therapy in multiple sclerosis. ACTH vs. placebo--final report.
Augustus S. Rose,Jan W. Kuzma,John F. Kurtzke,Norman S. Namerow,William A. Sibley,Wallace W. Tourtellotte +5 more
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This article is published in Neurology.The article was published on 1970-05-01. It has received 252 citations till now. The article focuses on the topics: Placebo & Clinical trial.read more
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Book ChapterDOI
Slowing the Progression of Multiple Sclerosis
TL;DR: This chapter highlights key trials to point out results of historical significance and to relate interferon therapy to disease pathogenesis, and concludes with the hope that advances in understanding pathology and pathogenesis can lead to even more rapid progress over the next 20 years.
Book ChapterDOI
Multiple Sclerosis: Experience with Large Clinical Trials
TL;DR: Until recently, multiple sclerosis was considered largely an untreatable disorder, but the last decade has been a period of great advances, culminating in the licensure of three agents demonstrated to be of benefit in relapsing MS.
Journal Article
Milestones in Neurology in the Last 50 Years on Multiple Sclerosis
TL;DR: A well documented case, before the disease was recognized in medical circles, is the case of Augustus d'Este, George III's grandson, who had been writing a detailed journal since 1822 and followed the progression of his disease during several decades.
Management of Optic Neuritis
TL;DR: Arguments in favor of, and against, treat- ment of presumed demyelinating optic neuritis are presented along with representative corticosteroid treatment regimens.
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