Open Access
DANMAP 2016 - Use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark
Birgitte Borck Høg,Helle Korsgaard,Ute Wolff Sönksen,Flemming Bager,Valeria Bortolaia,Johanne Ellis-Iversen,Rene S. Hendriksen,Lars Bogø Jensen,Karl Pedersen,Tine Dalby,Kristina Træholt Franck,Anette M. Hammerum,Henrik Hasman,Steen Hoffmann,Katrin Gaardbo Kuhn,Anders Rhod Larsen,Jesper Larsen,Eva Møller Nielsen,Stefan S. Olsen,Andreas Petersen,Louise Roer,Sissel Skovgaard,Mia Torpdahl,Veronika Vorobieva +23 more
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Borck Høg, Birgitte; Korsgaard, Helle Bisgaard; Wolff Sönksen, Ute; Torpdahl, Mia; Vorobieva, Veronika as mentioned in this paper.Abstract:
Borck Høg, Birgitte; Korsgaard, Helle Bisgaard; Wolff Sönksen, Ute; Bager, Flemming; Bortolaia, Valeria; Ellis-Iversen, Johanne; Hendriksen, Rene S.; Borck Høg, Birgitte; Jensen, Lars Bogø; Korsgaard, Helle Bisgaard; Pedersen, Karl; Dalby, Tine; Træholt Franck, Kristina ; Hammerum, Anette M; Hasman, Henrik; Hoffmann, Steen; Gaardbo Kuhn, Katrin; Rhod Larsen, Anders; Larsen, Jesper; Møller Nielsen, Eva; Schytte Olsen, Stefan; Petersen, Andreas; Roer, Louise; Skovgaard, Sissel; Wolff Sönksen, Ute; Torpdahl, Mia; Vorobieva, Veronikaread more
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Incidence of invasive meticillin-resistant Staphylococcus aureus infections in Germany, 2010 to 2014
TL;DR: This analysis corroborates previous findings that the incidence of invasive MRSA infections in Germany may be declining and calculates risk ratios between consecutive years, stratifying cases by sex, age and federal state of residence.
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Bats as a reservoir of resistant Escherichia coli: A methodical view. Can we fully estimate the scale of resistance in the reservoirs of free-living animals?
Aneta Nowakiewicz,Przemysław Zięba,Sebastian Gnat,Aleksandra Trościańczyk,Marcelina Osińska,Dominik Łagowski,U. Kosior-Korzecka,Iwona Puzio +7 more
TL;DR: Bats should not be neglected as another environmental reservoir and as an unpredictable source of potential pathogenic and multidrug resistant bacteria and should be extensively studied to predict the direction of the development and range of spreading resistance.
Journal ArticleDOI
Evaluating integrated surveillance of antimicrobial resistance: experiences from use of three evaluation tools
TL;DR: This study provides guidance on aspects to consider when choosing between available tools and embarking on an evaluation of integrated surveillance.
Journal ArticleDOI
The association between measurements of antimicrobial use and resistance in the faeces microbiota of finisher batches.
Vibe Dalhoff Andersen,L. V. De Knegt,Patrick Munk,M. S. Jensen,Yvonne Agersø,Frank Møller Aarestrup,Håkan Vigre +6 more
TL;DR: The study shows that Lifetime Exposure is an efficient measurement of AM use in finisher batches, and has a significant effect on the occurrence of resistance, measured either by cultivation or metagenomics.
Journal ArticleDOI
Prediction of antimicrobial resistance in clinical Campylobacter jejuni isolates from whole-genome sequencing data
Louise Gade Dahl,Katrine Grimstrup Joensen,Mark T. Østerlund,Kristoffer Kiil,Eva Møller Nielsen +4 more
TL;DR: It is found that WGS can predict antimicrobial resistance with a high degree of accuracy and have the potential to be a powerful tool for AMR surveillance.
References
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Frequency and Evolution of Azole Resistance in Aspergillus fumigatus Associated with Treatment Failure
Susan J. Howard,Dasa Cerar,Michael J. Anderson,Ahmed Albarrag,Matthew C. Fisher,Alessandro C. Pasqualotto,Michel Laverdière,Maiken Cavling Arendrup,David S. Perlin,David W. Denning,David W. Denning +10 more
TL;DR: An increase in the frequency of azole-resistant Aspergillus fumigatus has emerged and it is feared that this phenomenon may be linked to the spread of E.coli.
Iconographies supplémentaires de l'article : Azole resistance in Aspergillus fumigatus : a side-effect of environmental fungicide use?
Abstract: Invasive aspergillosis due to multi-azole-resistant Aspergillus fumigatus has emerged in the Netherlands since 1999, with 6.0-12.8% of patients harbouring resistant isolates. The presence of a single resistance mechanism (denoted by TR/L98H), which consists of a substitution at codon 98 of cyp51A and a 34-bp tandem repeat in the gene-promoter region, was found in over 90% of clinical A fumigatus isolates. This is consistent with a route of resistance development through exposure to azole compounds in the environment. Indeed, TR/L98H A fumigatus isolates were cultured from soil and compost, were shown to be cross-resistant to azole fungicides, and genetically related to clinical resistant isolates. Azoles are abundantly used in the environment and the presence of A fumigatus resistant to medical triazoles is a major challenge because of the possibility of worldwide spread of resistant isolates. Reports of TR/L98H in other European countries indicate that resistance might already be spreading.
Journal ArticleDOI
Azole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?
TL;DR: Azole resistance in Aspergillus fumigatus has now been reported from 6 continents and is emerging as a global health problem.
Journal ArticleDOI
A new probability formula for surveys to substantiate freedom from disease.
Angus Cameron,F C Baldock +1 more
TL;DR: A new formula is presented that calculates the exact probability of detecting diseased animals, and considers both imperfect tests and finite population size, and enables the accurate calculation of survey sample-size requirements, and the precise analysis of survey results.
Journal ArticleDOI
National Surveillance of Fungemia in Denmark (2004 to 2009)
Maiken Cavling Arendrup,B. Bruun,Jens Jørgen Christensen,Kurt Fuursted,Helle Krogh Johansen,Poul Kjaeldgaard,Jenny Dahl Knudsen,Lise Kristensen,Jens Kjølseth Møller,Lene Rostgaard Nielsen,Flemming S Rosenvinge,Bent Røder,Henrik Carl Schønheyder,Marianne Thomsen,Kjeld Truberg +14 more
TL;DR: The study confirmed an incidence rate of fungemia in Denmark three times higher than those in other Nordic countries and identified marked differences related to age and gender.
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DANMAP 2010: DANMAP 2010 - Use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark
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