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DANMAP 2016 - Use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark

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Borck Høg, Birgitte; Korsgaard, Helle Bisgaard; Wolff Sönksen, Ute; Torpdahl, Mia; Vorobieva, Veronika as mentioned in this paper.
Abstract
Borck Høg, Birgitte; Korsgaard, Helle Bisgaard; Wolff Sönksen, Ute; Bager, Flemming; Bortolaia, Valeria; Ellis-Iversen, Johanne; Hendriksen, Rene S.; Borck Høg, Birgitte; Jensen, Lars Bogø; Korsgaard, Helle Bisgaard; Pedersen, Karl; Dalby, Tine; Træholt Franck, Kristina ; Hammerum, Anette M; Hasman, Henrik; Hoffmann, Steen; Gaardbo Kuhn, Katrin; Rhod Larsen, Anders; Larsen, Jesper; Møller Nielsen, Eva; Schytte Olsen, Stefan; Petersen, Andreas; Roer, Louise; Skovgaard, Sissel; Wolff Sönksen, Ute; Torpdahl, Mia; Vorobieva, Veronika

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Drivers and Dynamics of Methicillin-Resistant Livestock-Associated Staphylococcus aureus CC398 in Pigs and Humans in Denmark.

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Assessment of the biodegradability of selected sulfa drugs in two polluted rivers in Poland: Effects of seasonal variations, accidental contamination, turbidity and salinity.

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The Risk of Some Veterinary Antimicrobial Agents on Public Health Associated with Antimicrobial Resistance and their Molecular Basis.

TL;DR: It was apparent from reviewing the published scientific literature that the ban on use of some antimicrobial agents did not change drug resistance patterns and did not mitigate the intended goal of minimizing antimicrobial resistance.
References
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Iconographies supplémentaires de l'article : Azole resistance in Aspergillus fumigatus : a side-effect of environmental fungicide use?

Abstract: Invasive aspergillosis due to multi-azole-resistant Aspergillus fumigatus has emerged in the Netherlands since 1999, with 6.0-12.8% of patients harbouring resistant isolates. The presence of a single resistance mechanism (denoted by TR/L98H), which consists of a substitution at codon 98 of cyp51A and a 34-bp tandem repeat in the gene-promoter region, was found in over 90% of clinical A fumigatus isolates. This is consistent with a route of resistance development through exposure to azole compounds in the environment. Indeed, TR/L98H A fumigatus isolates were cultured from soil and compost, were shown to be cross-resistant to azole fungicides, and genetically related to clinical resistant isolates. Azoles are abundantly used in the environment and the presence of A fumigatus resistant to medical triazoles is a major challenge because of the possibility of worldwide spread of resistant isolates. Reports of TR/L98H in other European countries indicate that resistance might already be spreading.
Journal ArticleDOI

Azole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles?

TL;DR: Azole resistance in Aspergillus fumigatus has now been reported from 6 continents and is emerging as a global health problem.
Journal ArticleDOI

A new probability formula for surveys to substantiate freedom from disease.

TL;DR: A new formula is presented that calculates the exact probability of detecting diseased animals, and considers both imperfect tests and finite population size, and enables the accurate calculation of survey sample-size requirements, and the precise analysis of survey results.
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