Journal ArticleDOI
Effect of Lactobacillus johnsonii La1 and antioxidants on intestinal flora and bacterial translocation in rats with experimental cirrhosis
Maite Chiva,Germán Soriano,Isabelle Rochat,Carmen A. Peralta,Florence Rochat,Teresa Llovet,Beatriz Mirelis,Eduardo Schiffrin,Carlos Guarner,Joaquim Balanzó +9 more
TLDR
Antioxidants alone or in combination with Lactobacillus johnsonii La1 can be useful in preventing bacterial translocation in cirrhosis.About:
This article is published in Journal of Hepatology.The article was published on 2002-10-01. It has received 129 citations till now. The article focuses on the topics: Lactobacillus johnsonii & Lactobacillus.read more
Citations
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Journal ArticleDOI
Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013
Rajiv Jalan,Javier Fernández,Reiner Wiest,Bernd Schnabl,Richard Moreau,Paolo Angeli,Vanessa Stadlbauer,Thierry Gustot,Mauro Bernardi,Rafael Cantón,Agustín Albillos,Frank Lammert,Alexander Wilmer,Rajeshwar P. Mookerjee,Jordi Vila,R. Garcia-Martinez,Julia Wendon,José Such,Juan Córdoba,Arun J. Sanyal,Guadalupe Garcia-Tsao,Vicente Arroyo,Andrew K. Burroughs,Pere Ginès +23 more
TL;DR: An in-depth review and a position statement on bacterial infections in cirrhosis are reported, which suggest that research on biomarkers of early infection may be useful in early diagnosis and treatment of infections.
Journal ArticleDOI
Bacterial translocation (BT) in cirrhosis.
TL;DR: This review delineates multiple mechanisms involved in the process of BT, with an emphasis on alterations in intestinal flora and mucosal barrier function, particularly immunological defense mechanisms.
Journal ArticleDOI
Bacterial infections, sepsis, and multiorgan failure in cirrhosis.
TL;DR: The mechanisms of bacterial translocation such as impaired immunity and bacterial overgrowth are reviewed, as well as maneuvers that may inhibit bacterial translocated and could be used not only to prevent infections but also to ameliorate the hyperdynamic circulatory state of cirrhosis.
Journal ArticleDOI
The role of the gut microbiota in nonalcoholic fatty liver disease
TL;DR: Although the best evidence to support a role for the gut microbiota in NAFLD and NASH comes largely from animal models, data from studies in humans (albeit at times contradictory) is accumulating and could lead to new therapeutic avenues for these highly prevalent conditions.
Journal ArticleDOI
Probiotics restore bowel flora and improve liver enzymes in human alcohol-induced liver injury: a pilot study
Irina A. Kirpich,Natalia V. Solovieva,Svetlana N. Leikhter,Natalia A. Shidakova,Oxsana V. Lebedeva,Pavel I. Sidorov,Tatjana A. Bazhukova,Andrej G. Soloviev,Shirish Barve,Craig J. McClain,Craig J. McClain,Craig J. McClain,Matthew C. Cave,Matthew C. Cave,Matthew C. Cave +14 more
TL;DR: It is concluded that patients with alcohol-induced liver injury have altered bowel flora compared to healthy controls and short-term oral supplementation with B. bifidum and L. plantarum 8PA3 was associated with restoration of the bowel flora and greater improvement in alcohol- induced liver injury than standard therapy alone.
References
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Journal ArticleDOI
A Randomized Placebo-Controlled Trial of Saccharomyces boulardii in Combination With Standard Antibiotics for Clostridium difficile Disease
Lynne V. McFarland,Christina M. Surawicz,Richard N. Greenberg,Robert Fekety,Gary W. Elmer,Kris A. Moyer,Sally A. Melcher,Karen E. Bowen,Jenny L. Cox,Zehra Noorani,Gregory Harrington,Moshe Rubin,David Greenwald +12 more
TL;DR: The combination of standard antibiotics and S boulardii was shown to be an effective and safe therapy for these patients with recurrent CDD, and a history of CDD episodes dramatically increased the likelihood of further recurrences.
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Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria.
TL;DR: Investigation of the inhibitory effect of LA 1 organisms against Caco-2 cell adhesion and cell invasion by a large variety of diarrhoeagenic bacteria found incubation before and together with enterovirulent E coli were more effective than incubation after infection by E coli.
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Lactobacillus species prevents colitis in interleukin 10 gene-deficient mice.
TL;DR: In the neonatal period, IL-10 gene-deficient mice have decreased levels of colonic Lactobacillus sp.
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Enhancement of the circulating antibody secreting cell response in human diarrhea by a human Lactobacillus strain.
TL;DR: The results indicate that Lactobacillus GG promotes recovery from rotavirus diarrhea via augmentation of the local immune defense, which is possibly relevant in protection against reinfections.
Journal ArticleDOI
Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: Results of a double‐blind, placebo‐controlled trial
Pere Ginès,Antoni Rimola,Ramon Planas,Victor Vargas,Francesc Marco,Manuel Almela,Montserrat Forné,Maria Luisa Miranda,Josep Llach,Joan Manuel Salmerón,Maria Esteve,Josep Maria Marques,María Teresa Jiménez de Anta,Vicente Arroyo,Joan Rodés +14 more
TL;DR: Results indicate that long‐term selective intestinal decontamination with norfloxacin is an effective and safe measure to prevent spontaneous bacterial peritonitis recurrence caused by aerobic gram‐negative bacilli in cirrhosis.