Journal ArticleDOI
Effects of TiO2 nanotubes with different diameters on gene expression and osseointegration of implants in minipigs.
TLDR
TiO(2) nanotubes can modulate bone formation events at the bone-implant interface as to reach favorable molecular response and osseointegration and the diameters of nanot tubes can be precisely controlled in order to obtain better bone formation.About:
This article is published in Biomaterials.The article was published on 2011-10-01. It has received 279 citations till now. The article focuses on the topics: Osseointegration & Implant.read more
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Journal ArticleDOI
The effect of titanium with electrochemical anodization on the response of the adherent osteoblast-like cell.
TL;DR: Using electrochemical anodization after sand blasting, and acid etching of Ti surface (SLA), SLA specimens with the high wettability of the thick TiO2 layer (SLAffinity) surface was developed to superimpose the nanoscale topographies on the microscale roughness of SLA surface without greatly altering the surface features.
Journal ArticleDOI
Lateral Spacing of TiO2 Nanotubes Modulates Osteoblast Behavior.
Madalina Georgiana Necula,Anca Mazare,Raluca Ion,Selda Ozkan,Jung Park,Patrik Schmuki,Anisoara Cimpean +6 more
TL;DR: The findings provide the proof that lateral spacing of the TiO2 nanotube coated titanium (Ti) surfaces has to be considered in designing bone implants with improved biological performance.
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Osteogenic activity and angiogenesis of a SrTiO3 nano-gridding structure on titanium surface
Zheni Gong,Haoyan Cheng,Meng Zhang,Xi Liu,Yan Zeng,Kaiwen Xiang,Yuan Xu,Yinwei Wang,Zhihong Zhu +8 more
TL;DR: The in vitro studies indicated that NG-Sr samples with nanoscale topography and long-lasting Sr release could enhance the biofunction of both osteoblast-like cells and human umbilical vein endothelial cells to varying degrees.
Journal ArticleDOI
Facile electrochemical synthesis of antimicrobial TiO2 nanotube arrays
Yu Zhao,Qi Xing,Jagadeesh Janjanam,Kun He,Fei Long,Ke Bin Low,Ashutosh Tiwari,Feng Zhao,Reza Shahbazian-Yassar,Craig R. Friedrich,Tolou Shokuhfar +10 more
TL;DR: The results of this study indicated that antimicrobial properties could be added to nanotextured medical implants through a simple and cost effective method.
Journal ArticleDOI
Selective biofunctional modification of titanium implants for osteogenic and antibacterial applications
Shi Qian,Yuqin Qiao,Xuanyong Liu +2 more
TL;DR: The diverse modifications of titanium orthopedic implants for selective biofunctionalization are highlighted, which include organized nanostructures and micro/nano-hybrid structures, inorganic component incorporation and external field assistance including the applications of photoirradiation, electrical stimulation and electromagnetic field.
References
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Journal ArticleDOI
Matrix elasticity directs stem cell lineage specification.
TL;DR: Naive mesenchymal stem cells are shown here to specify lineage and commit to phenotypes with extreme sensitivity to tissue-level elasticity, consistent with the elasticity-insensitive commitment of differentiated cell types.
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The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
Kazuhisa Nakashima,Xin Zhou,Gary R. Kunkel,Zhaoping Zhang,Jian Min Deng,Richard R. Behringer,Benoit de Crombrugghe +6 more
TL;DR: It is proposed that Runx2/Cbfa1-expressing preosteoblasts are still bipotential cells, because Osx null preostEoblasts express typical chondrocyte marker genes, and Osx acts downstream of Runx 2/C bfa1.
Journal ArticleDOI
Titanium oxide nanotube arrays prepared by anodic oxidation
Dawei Gong,Craig A. Grimes,Oomman K. Varghese,Wenchong Hu,R. S. Singh,Zhi Chen,Elizabeth C. Dickey +6 more
TL;DR: In this article, the average tube diameter, ranging in size from 25 to 65 nm, was found to increase with increasing anodizing voltage, while the length of the tube was found independent of anodization time.
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Osteoinduction, osteoconduction and osseointegration.
TL;DR: Osseointegration is the stable anchorage of an implant achieved by direct bone-to-implant contact in craniofacial implantology and this mode of anchorage is the only one for which high success rates have been reported.
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Stem cell fate dictated solely by altered nanotube dimension
TL;DR: Altering the dimensions of nanotubular-shaped titanium oxide surface structures independently allowed either augmented human mesenchymal stem cell (hMSC) adhesion or a specific differentiation of hMSCs into osteoblasts by using only the geometric cues, absent of osteogenic inducing media.