Journal ArticleDOI
Effects of TiO2 nanotubes with different diameters on gene expression and osseointegration of implants in minipigs.
TLDR
TiO(2) nanotubes can modulate bone formation events at the bone-implant interface as to reach favorable molecular response and osseointegration and the diameters of nanot tubes can be precisely controlled in order to obtain better bone formation.About:
This article is published in Biomaterials.The article was published on 2011-10-01. It has received 279 citations till now. The article focuses on the topics: Osseointegration & Implant.read more
Citations
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Journal ArticleDOI
Potassium Titanate Assembled Titanium Dioxide Nanotube Arrays Endow Titanium Implants Excellent Osseointegration Performance and Nerve Formation Potential
TL;DR: Using an electrochemical technique and a hydrothermal approach, a potassium titanate nanoroddecorated titanium oxide (K2Ti6O13-TiO2) nanotube array is constructed on the surface of titanium implants as mentioned in this paper .
Journal ArticleDOI
Fit and Forget: The Future of Dental Implant Therapy Via Nanotechnology.
TL;DR: A review of the latest developments, challenges and future directions in this domain to enable the successful fabrication of clinically-translatable therapeutic dental implants that would allow for long-term success, even in compromised patient conditions is presented in this paper .
Book ChapterDOI
Drug-Eluting Nanotubes for Cellular Bioactivity
TL;DR: The mechanism behind the cellular interaction with the nanotubes possessing different diameter has been reported in this chapter and slow and controlled release of drug from the polymer-encapsulated drug has been the current area of research.
Book ChapterDOI
An Evaluation on the Effect of Osteoporosis on Osseointegration Around Titanium Implants in Posterior Maxilla Following a Tooth Extraction
N. Doan,N. Doan,Zhibin Du,J. Xiao,Peter Reher,W. Xia,Ross Crawford,Saso Ivanovski,F. Yang,Q. T. Duong,J. Jiang,Yin Xiao +11 more
TL;DR: It is demonstrated that osseo-integration was inferior in implants following extraction in the posterior maxilla of OVX rats, especially in the early healing period, indicating that lower local bone quality in OVx rats can reduce early bone formation on implant surfaces.
Dissertation
Effect of surface characteristics on cellular adherence and activity
TL;DR: In this article, the authors discuss the effect of different modifiers on the performance of different types of implantations, such as titany and titan modifiers, and the effects of different combinations of modifiers on implantation performance.
References
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Journal ArticleDOI
Matrix elasticity directs stem cell lineage specification.
TL;DR: Naive mesenchymal stem cells are shown here to specify lineage and commit to phenotypes with extreme sensitivity to tissue-level elasticity, consistent with the elasticity-insensitive commitment of differentiated cell types.
Journal ArticleDOI
The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
Kazuhisa Nakashima,Xin Zhou,Gary R. Kunkel,Zhaoping Zhang,Jian Min Deng,Richard R. Behringer,Benoit de Crombrugghe +6 more
TL;DR: It is proposed that Runx2/Cbfa1-expressing preosteoblasts are still bipotential cells, because Osx null preostEoblasts express typical chondrocyte marker genes, and Osx acts downstream of Runx 2/C bfa1.
Journal ArticleDOI
Titanium oxide nanotube arrays prepared by anodic oxidation
Dawei Gong,Craig A. Grimes,Oomman K. Varghese,Wenchong Hu,R. S. Singh,Zhi Chen,Elizabeth C. Dickey +6 more
TL;DR: In this article, the average tube diameter, ranging in size from 25 to 65 nm, was found to increase with increasing anodizing voltage, while the length of the tube was found independent of anodization time.
Journal ArticleDOI
Osteoinduction, osteoconduction and osseointegration.
TL;DR: Osseointegration is the stable anchorage of an implant achieved by direct bone-to-implant contact in craniofacial implantology and this mode of anchorage is the only one for which high success rates have been reported.
Journal ArticleDOI
Stem cell fate dictated solely by altered nanotube dimension
TL;DR: Altering the dimensions of nanotubular-shaped titanium oxide surface structures independently allowed either augmented human mesenchymal stem cell (hMSC) adhesion or a specific differentiation of hMSCs into osteoblasts by using only the geometric cues, absent of osteogenic inducing media.