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Open AccessJournal ArticleDOI

Electrochemical biosensors based on nanomodified screen-printed electrodes: Recent applications in clinical analysis

TLDR
In this paper, a review of recent advances in the development of screen-printed electrode-based biosensors is presented, together with examples of paper-based electrochemical devices, of multiple detections using arrays of screen printed electrodes, and of the most recent developments in the field of wearable sensors.
Abstract
This review addresses recent advances in the development of screen-printed electrode based biosensors modified with different nanomaterials such as carbon nanotubes, graphene, metallic nanoparticles as gold, silver and magnetic nanoparticles, and mediator nanoparticles (Prussian Blue, Cobalt Phthalocyanine, etc.), coupled with biological recognition elements such as enzymes, antibodies, DNA and aptamers to obtain probes with improved analytical features. Examples of clinical applications are illustrated, together with examples of paper-based electrochemical devices, of multiple detections using arrays of screen printed electrodes, and of the most recent developments in the field of wearable biosensors. Also the use of smartphones as final detectors is briefly depicted.

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Journal ArticleDOI

Disposable Sensors in Diagnostics, Food, and Environmental Monitoring.

TL;DR: A brief insight into the materials and basics of sensors (methods of transduction, molecular recognition, and amplification) is provided followed by a comprehensive and critical overview of the disposable sensors currently used for medical diagnostics, food, and environmental analysis.
Journal ArticleDOI

Advanced Materials for Printed Wearable Electrochemical Devices: A Review

TL;DR: A review of the key material requirements for ink formulations for realizing efficient wearable electrochemical systems such as batteries, supercapacitors, biofuel cells and sensors is presented in this article.
Journal ArticleDOI

Point-of-care testing based on smartphone: The current state-of-the-art (2017-2018).

TL;DR: A comprehensive review of the development of smartphone-based POCT devices over the past two years and assessed their relative merits and drawbacks, illustrating that the various technological and economical requirements are urgent and tremendous.
References
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Journal ArticleDOI

Measuring the accuracy of diagnostic systems

John A. Swets
- 03 Jun 1988 - 
TL;DR: For diagnostic systems used to distinguish between two classes of events, analysis in terms of the "relative operating characteristic" of signal detection theory provides a precise and valid measure of diagnostic accuracy.
Journal ArticleDOI

Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices

TL;DR: Microfluidic paper-based analytical devices are a new class of point-of-care diagnostic devices that are inexpensive, easy to use, and designed specifically for use in developing countries.
Journal ArticleDOI

Simple telemedicine for developing regions: camera phones and paper-based microfluidic devices for real-time, off-site diagnosis.

TL;DR: A prototype system for quantifying bioassays and for exchanging the results of the assays digitally with physicians located off-site offers new opportunities for inexpensive monitoring of health, especially in situations that require physicians to travel to patients to obtain diagnostic information that might be obtained more effectively by less valuable personnel.
Journal ArticleDOI

Electrochemical biosensors: recommended definitions and classification.

TL;DR: In this article, the authors present a set of performance criteria for single-use biosensors, i.e., a device that is both disposable after one measurement, and unable to monitor the analyte concentration continuously or after rapid and reproducible regeneration.
Journal ArticleDOI

The enzyme electrode.

TL;DR: The enzyme electrode is a miniature chemical transducer which functions by combining an electrochemical procedure with immobilized enzyme activity to measure the concentration of glucose in biological solutions and in the tissues in vitro.
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